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GAHMKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPLYRDLLGDGSQFGVRFSYRVQEEPRGIADAFIVGKDFIGDSKVALVLGDNVFYGHRFSEILRRAASLEDGAVIFGYYVRDPRPFGVVEFDSEGRVISIEEKPSRPKSNYVVPGLYFYDNQVVEIARRIEPSDRGELEITSVNEEYLRMGKLRVELMGRGMAWLDTGTHDGLLEASSFIETIQKRQGFYIACLEEIAYNNGWITREDVLEMAEKLEKTDYGKYLRDLAEGNFHG

GAHMKGIVLAGGSGTRLYPITRAVSKQLLPIYDKPMIYYPLSVLMLAGIRDILIISTPRDLPLYRDLLGDGSQFGVRFSYRVQEEPRGIADAFIVGKDFIGDSKVALVLGDNVFYGHRFSEILRRAASLEDGAVIFGYYVRDPRPFGVVEFDSEGRVISIEEKPSRPKSNYVVPGLYFYDNQVVEIARRIEPSDRGELEITSVNEEYLRMGKLRVELMGRGMAWLDTGTHDGLLEASSFIETIQKRQGFYIACLEEIAYNNGWITREDVLEMAEKLEKTDYGKYLRDLAEGNFHG

   HKGIILAGGSGTRLHPITRGVSKQLLPIYDKP-IYYPLSVL-LAGIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQV-DPERFGVVEFDDNFRAISLEEKPKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQ-YLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRA

  KRKGIILAGGSGTRLHPATLAISKQLLPVYDKPMIYYPLSTLMLAGIREILIISTPQDTPRFQQLLGDGSNWGLDLQYAVQPSPDGLAQAFLIGESFIGNDLSALVLGDNLYYGHDFHELLGSASQRQTGASVFAYHVLDPERYGVVEFGG--KAISLEEKPLEPKSNYAVTGLYFYDQQVVDIARDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQFIATLENRQGLKVACPEEIAYRQKWIDAAQLEKLAAPLAKNGYGQYLKRLLTE--TV

 KMRKGIILAGGSGTRLYPVTMAVSKQLLPIYDKPMIYYPLSTLMLAGIRDILIISTPQDTPRFQQLLGDGSQWGLNLQYKVQPSPDGLAQAFIIGEEFIGGDDCALVLGDNIFYGHDLPKLMEAAVNKESGATVFAYHVNDPERYGVVEFGT---AISLEEKPLEPKSNYAVTGLYFYDNDVVLMAKNLKPSARGELEITDINRIYLEQGRLSVALMGRGYAWLDTGTHQSLIEASNFIATIEERQGLKVSCPEEIAFRKGFIDVEQVRKLAVPLIKNNYGQYLYKMTKD

  SNFAIILAAGKGTRMKS---DLPKVLHKVAGISMLEHVFRSVGAIQPEKTVTVVG-HKAELVEEVLAGQ------TEFVTQSEQLGTGHAVMMTEPILEGLHTLVIAGDTPLIT-ESKNLIDFH--IKNVATILTAETDNPFGYGRIV------VLRIVEQK-KQIKEINTGTYVFDNERLFEALKNIAQ---GEYYITDVIGIFRETGEKVGAYTLKDFDELGVNDRVALATAESVMRRRINHKH---------------DVE-------------KGQTK

  AMSVVILAAGKGTRMY---SDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYG-HGGDLLKQALKDD-----NLNWVLQAEQLGTGHAMQQAAPFFADEDILMLYGDVPLI---SVETLQRLRDKQGGIGLLTVKLDDPTGYGRITRG---KVTGIVEHQRQI--QEINTGILIANGDMKRWLAKLTNNNQGEYYITDIIALAYQEREIVAVHPQ-RLSVEGVNNRLQLSRLERVYQSEQ-AE-LR----------------------------IEGNV

 SKAVIVIPARYGSSRL------PGKPLLDIVGKPMIQHVYERALQVAVAEVWVATDDPRVEQAVQAFGG-------KAIMTRNDHESGTDRLVEVMHKVEADIYINLQGDEPM----RPRDVETLLQGMLPVATLCHAISEAPSTVKVVVNTRQDALYFS--RSPIPRYLKHVGIYAYRRDVLQNYSQLPEEQ----EQLRL-M---GI-NIRTFEVA--ATGPGVDTPACLEKVRALMAQEL

EIRVKAIILAAGLGTRLRPLTENTPKALVQVNQKPLIEYQIEFLKEKGINDIIIIVG-YLKEQFDY-LKEKY----GVRLVFNDKYYNNFYSLYLVKEE---ANSYVIDADNYLFK------FR--NDLTR-STYFSVYREDC-NEWFLVYGDDYKVQDIIVDSK----GRILSGVSFWDAPIVSFIDKAEF---VDLYWDNVKDN-IKELDVYVEELEG-NSIYEIDSVQDYRKLEEILK

PPHLAALVLARGSKG-------IPLKNIKRLAGVPLIGWVLRAALDAGFQSVWVSTD---HDEIENVAK-----GA-QVHRRSSETSTSLDAIVEFLYHNEVDIVGNIQATSPCL---HPTDLQKVAEMGYDSVFSVVRRHQ----------------------LN--ELYENGSFYFAKRHLIEMG---------------YLQGG----KMAYYEMRA-EHSVDID--IDWPIAEQRVLR--------YFG

MTTITGVVLAGG---------GGVDKGLLELNGKPLWQHVADALMTQLSHVVVNANR--HQEIYQA-SG--------LKVIEDDY-PGPLAGMLSVMQQEAGEWFLFCPCDTPYI---PPDLAARLNH-DAPVVWVHDG-------------------------------ERDHTIALVNRAIEPLLLEYAGE----RRVMVFMRLAG----GHAVDFSDKDAFVNVNTPEELARWQ

   SFVVIIPARYAST----PG--KP--DI--NKHVLERARES----GAERIIVATDHEVARAVEAAGG----------EVCTR---GTERLAEVVECAFSDDTVIVNVGDEIP----T---QADNLAQRQVGATLAVPIHEAPNAVKVVLDAEGYALYFS--RATIPNFLRHLGIYGYRGFIRRYVNWQP-H-------E--QLRVLYGEKIHVAVAQ--VPGTGVDTPEDLERVAE

 KRKNIALIPAA-------------KQYVEIGSKTVLEHVLGIFHE-AVDLTVVVVSPEDADKVQTAFPQ-------VRVWKNGGQTRAETVRNGVAKLAAEDNILVHDAARCCLP-EA-ARLIEQAGNAAEGGILAVPVAD----------------------VDRSGLWQAQTPQLFQAGLLHRALAAE-------TD--EASAVEKGVRPLLIQG---ARNLKLTQPQDAYIVRLLLD

 LDVCAVVPAA-------------PKQYLSIGNQTILEHSVHALLAHPRVKRVVIAISSRFAQ--LPLANHP----QITVVDGG--DERADSVLAGLKAAGDAWVLVHDAARPC----HQDDLARLLALSRTGGILAAPVRD----------------------RVRNGLWHALTPQFFPRELHDCLTRAGAT----ITDSALEYCGF---HPQLVEGR--ADNIKVT--EDLALAEFYL

EKQNIAVILAR-NSKGL--PL----KNLRK-NGISLLGHTINAAISSCFDRIIVSTD---GGLIAEEAK---NFG--VEVVLRPELASSISGVIHALEGSNSGTVTLLQPTSPLR--AHREAFSLF-DEKIKGSVVSACPEH------------------------PLAFRPNGAIYINDASLIANN--------------CFF--I----APTKLYIS---DSIDIDTELDLQQAENILNH

  SFTVIIPAR------------------------PIQHVFEKALQSGASRVIIATDNENVADVAKSFG--------AEVCTSVNHNSGTERLAEVVLAIPDEIIVNIQGDEPLI---PPVIVRQVADNLAVNASLAVKIEELFNAVKVLTDKDGYVLYFSRS---VIPYLRHIGIYAYRAGFIKQYVQWAPN----KLEQLRVL---GE-RIHVEL

ALDSFTLIMQT-------------YNRTDL----RLLNH-YQ--AVPSLHKVIVVWNNV--KGPEELWN--GPHPIPVIFKPQTKMRNRLQ----VFPEVETNAVLMVDDDTLIS--QDLVFAFSIWQQFPDQIIGFV---------PR----------KHYG--ELDQ-----GASFFNSKYLELFQKQHAL-ETQNDDIAMNFLVTRTGKGIFVKP---INMVNL

 MTIYVVTPTY------------RLVQK------AELVRLSQTLSLVPRLHWLLVEDAEPTPLVSGLLA----GLLFTHLVVLTPHPRGVEQRNKALDWLR-GVVYFADDDNTYS----RELFEEMRWTRGVSVWPVGL------VGEGPQVQ-GRVGFTAW----------VDMAFAVALL--NAQ----TAPR--HLESSLL-S--DPKDLEPRRV-------TRTEK

LAVIPILVIAC--------------DRS-------TVRRCLDKLLYRP-FPIIVSQD-GH-AQVIASYGSA------VTHIRQPDKRHYRWALGQIFHNFNYPAAVVVEDDLEV----APDFFEYFQATYPWCVSAWNGKE------------LYRTDFF------------PGLGWLLLAELWAELEPKWP---KA-WDDWM---QRK-RACVRPEI-----MTFG

 PTIHVVTPTY------------RPVQK------AELTRMANTLLHVPNLHWLVVEDAP-TPLTARLLR---TGLNYTHLHVETP-IPGTMQRNLALRWLR-GVVYFADDDNTY----SLELFEEMRSTRRVSVWPVA-------VGEAPRVGAGV-RW-VF----------IDMAFAVNLLI-QAY----GVKG---QESSLLR-LVTLNDLEPKKI-------TRTEK

KPKACYVTLVR-------------NKEL------KGLLSSIKYVEKIFPYPWVFLNDEPFTEEFKEAVT----VSSEVKFGILPKHMCQSFFWRH-ELLEEYDWYWRVEPDIKLY---CDI-YD-VFWMQKVYGFTV----------SI-----------HEYETYN---CHFWNFEIANLNLWRSYRYFLD-GFF--DAPVHSIAAALFLKIHYFSD----GYHHP

QNKVAVLLLAGGQ--------VAYPKGMYDVGRKTLFQIQAERILKLQIIPWYIMTSGRTMESTKEFFTYF--GLKNVIFFQQGMPDGNGGLYALIVEDMEIWSIHVYCVDNIL--------DPRFIGCIADCGAKVVEKTN--PVGVVC--------YQVVEIST-LFNAGNIANHFFTVPFLRDVVYEPLQHHMEKFVFDIFQFA---KKFVVYEVLRE--FSPLKNNGKDNTARHAL--MSPI-CEI-----SPLIS---------------------------------SY

 PKVSVIMTSY--------------NKS------DYVAKSISSILSQTSFELFIMDDNSN--TL-NVIRLND---RVRFYQS--KTR-YAALINQAIEMAEGEYITYATDDNIY----MPDRLLKMVRELKAVIYSASV--------------AQVTWNAPC---------AIDCSVMHRYSVLEKVKF--SP--AF-GDARFFWRVNHFYPFYPLDE---ELNYI

    DIVFAADDN-----------AYLC------VAAKSV-------TEIRFHVLDAGINRAAVAANL---GGGG-NIRFIDVNPSITTYARLK-LGEYIACDKVLYLDIDVLVRD---TPLWDT--DLGDNWLGAS---------DL-------------VERQ-YKADG--GVLLINLKKW-DIFKSS--VEYK--DQDILNGLFK--GGVCYANSTVPVAVS-PWHRDC--AER--FTE

 ITVGLTVFAV-------------GRYIEH-----YLEEFLT-ANHFV-VIFYIVD---DVSR---PL----ELGRSFKVFKIKDI-SRKTIGEHIVAHIQHVDFLFCDVDQVFQD---K--FGET--LGESVAQLQAWKADPFT------------DFY------------HAAIFGGTPTVLNITQEKGLKDK-WHDEHL-NKYFLLNKPTKILSPDIK--WQT

 TDQAFVTLTT-------------DAYA------KGALVLGSL--KTS-RRLAVLTTPQVSDTMRKALEIV-----DEVITVDIL-GVTLTKLH-C-SLTQ-SKCVFMDADTLV----LAN-IDDLFER-EELSAAPD-------PGWPD--------------------CFNSGVFVYQPSTYNQLLHVASGF-GG-DQGLLNTFF--NSWKHLPFIFGAN-HFLGQT----SV-----------------------------------------PTMTHPQFLNVWWDI

 PHKVAIIIPF-------------RNRQE------HLKYWLYL-PILLDYGIYVINQAG-------------------------SMFNRAKLLNVGFKAL--YNCFVFSDVDLIPM--NDHNTY--RCF-SQPRHIVAFS-------PYV--------QY------------GGVSALSKQQFLSING--PNN--YW-EDDDIYNRLAFGMSVSRPNAV--KCRMI-----RHSR

  TTIGLTVFAI------------AFLK------LFLETAEKHFMV-GHRVHYYVFTDQ-PAAV-PRV-----TGRQLSVLEVR-----------CERRFLSDYLVCVDVDMEFRDH-----GVEIL---TPLFGTL-----PG---FYG-----------YIPKDEGD-FYYLGFFGGSVQEVQRLTRACAV-----HDESHLNKYL-LRHKPVLSPERKLRFTAVP

 IPVVLLACGS-------------FNPI-----TNMHLRMFEVARDHLVIQGIISPSHHRVAMARLALQ---TSD-WIRVDPWEQWMETVKVLRHHHSKLLVPELKLLC------------------------------------TF--------------QT-------------------------------------DAHIQEE-----MHQH-------------------EI

  QSTLVIAEH-----------NDS--LA-----PITLNTITAATRLGGEVSCLVAGTKCDKVAQDLCK---AG-IAKVLVAQHVYELTPLILATQKQF---NYTHICA-GADII---AIK-SPDT--------FVRTIYA----------------------------------------KV--------------AT--GGS

   SKILVIAH---------RRND---LR-----PVSLELIGAANGLKDKVVVAVIGSQA-DAFVPALS---NG-VDELVVVKGSDVFE-SVSALIAAHN---PSVVLL-PHDVYI-----VEYQ--DE---LVAT-RGGYN----------------------------QVD-TI----------------------------------------------SRSQNKD

  GCTALVTG----------------SR------GIGYGIVEELA--LGASVYTCSR--NQKELNDCLT-WRSKGFKVEASVCDSER--QELMNTVANHFHGKLNILVNNA-------------------ERGNV-SSGAL-VPGATRC-------AFE------------------------------------------------W--KDNIRNGV-----GPG------------VIARM

 RQILVAF----------------------------GGLDSTVLLHQL-LRAIHVHHGLSADAWVTHCENCQQWQVPLVVERVQLAQARQARYQAFARTLLPEVLVTA--QH---------------------------------ETF----------AGL-----------AE-------EFAGRL-----------------------------AR----TR-------------------------QY--DDLA------------LQI------DARRAAIIRRWLA

  GTTALVTG-----------------K------GIGYAIVEELAG-LGARVYTCSR--NEKELDECLE-WREKGLNVEGSVCDLSR--RDLMQTVAHVFDGKLNILVNNA------------------SQNGNV--SIGFSSAGAMTK-------ACE-----------------------------------------------WA--KDNIR--------APG--------VILAGK

  GKVVVITG-----------------T------GLGKSMAR-FA--EKAKVVVNYR-SKEDEANSVLE-IKKVGGEAIAVKGDVTVEVINLVQSAIKEFG-KLDVMINNA-------------------DIKGT-SSVHIPAALMTEAL--------E------------------------------------------------Y--PKGIRNIG---PG------------NAE-------GY--EP

MKSLQALFGGT------------DPVH------YGHLKPVETLANLIGLTRVTIIPNVQRKHMLELAIA-KP---LFTLDEREL-PSYTAQTLKEW----QGVPLAFII--GCREDHN-----PEDLHLQPAGKIY-------------------------------------------------------------------------------------WF-ISA---TIIR-LL

   MKVLVPVKR--SGV----LVKM-MN-------PDEIAVEEAIRLK-EIIAVSIGVKQAAETLRTAL---AM-GADRAILVVAIAVAKILAAVARAEG--TELIIAG-AI--FA-SK--VEIE--GA-------REVDG-------------TI---------------------LP------------RLEV

  DSKFGFIVIDGS-DLPKKRH----YVR-----KVAETAVQLFISGNVAGLVLAGSADFKTELSQSD--QS----KVLKLVDISYNGFNQAIELSTEVLS

  APLIVVATQ--------------GGK--------ARAVRKY----PDATILALTTNEKTAHQLVLS--------GVVPQLVKEITSTDDFYRLGKELALGDVVVMVS-TT-------------------------------------------------------------NTASVHVL

  MKILVAVK-QT-MDVDEF-MMYD-LN------EWDDFSLEEAMKIK-EVVVVSVGPDRVDESLRKCL---A-GADRAVRVWDASVVGRILTEVIKKEA--PDMVFAG--V-VVA--DLQ-YK--PGD---------LE-ML-----------EV---------------EI------CP----------MSRV

  AKAMVVLSN--------------TGR--------ARLVAKY-R--PNCPIVCVTTRLQTCRQLNIT--Q-----GVESVFFDAHDEKEHRVAAGVEFAKGDYCVVIHA---------------------------------------------------------------NQTRILLVE

   AVLLLGEVT--NG----------NR------DATAKAVAAVKALGDV-TVLCAGAS-AKAAAEEAA---AGVAKVLVAEYGHRLA--PTAALIVGLA-GDYSHIAAPAT-VS---AIL-DADT---------ERPIGN-----------AIQ-------------------TI-------------PGLS--SW-------------------------------AES-DRPE

  GSTCVVFG----------------LG------GVGLSVIMGCKSAGASRIIGIDL---NKDKFEKAM---AVGA-TECISPKSTK---PISEVLSEMTGNNVGYTFEVI-------------------NYGT----------MLT-----------------------------------------------------YD--PMLLFT-GRTWK------VF------------------V---VTEF

  NKTIIVTG-----------------R------GIGLAFTRAVA--AGANVAVIYRS--AADAVEVTEKGKEFGVKTKAYQCDVSNT---VTKTIQQIDAGPISGLIAN--GV----------------QKGSI------SS---------------------------AAC---------------------------LVLAAEW---SAGIRNA-----SPG-------------YV-RF------QPE

   EVVLLACGS--------FNP----IT-----NHLRLFELAKDYNTVVKGIISPVAYHRVIAELATK---NSK-WVEVDTWEEWKETLKVLRHHEK-LE-VPKVKLLCG--------------------------------------------------------------------------------KS-----DITQIVA--------------------------------------------------CVT-----RAGNDAQKFIYESDVL---HR--IHV

 SDKVVAIIVT--SEN--LLAR------YD---EGAIKILMQRLYDQGHRNISYLGVPHTGKRRHEAYLACKAHKLHPVAALPGLAM---Y--ENVAKVITP-TLQLASVGTV

  GATVAVLGI-------------PVGL------MAVAGAKLR----GAGRIIAVGSRPCVDAAKYYG--------ATDIVNYK-DG---PIESQIMNLTEGKGVDAAIIA---------------------PG--NY------GEV-----------------------------------------------------PVPRLEWGC-GMAHKT-------GLC---------PGGRME-RL

  KKVALVTG----------------QG-------IGKAIALRLVKDGF-AVAIADY--NDATAKAVASEINQAGGHAVAVKVD-VS----VFAAVEQARK-GFDVIVNN--------------------HGGKI--GHVG-----------------------------FAV-------------------------LT-TAARDLAPL-GITVN-----PG------------MWA----RL-----EPE

  YKHILVAVD-------------SEES------PILLKKAVGIAKRHDAKLSIIHV--TQKALLDLAE---DY-PISEKLSGSGDLG-QVLSDAIEQYD----DLLVTGH------------------------------------FW---------------------SKLM------------------------QVMNTK---------------------PL-----RD

  KKIGIFGGT------------DP-PH-----NGHLLMANEVLYQAGLDEIWFMPNFHRVEMLKLAIQ-NP----SFKLELEMGPSYTFDTVSLL-QRYPNDQLFFII--G-------------NL-----QF--VKRPG------HVE-------TP----------------------------------------------------PLLFADVP--EF-VSSTMRE---LIP

 MKTIGILG-GM-GPLNPQI-PDR-CNTAHII--SMIEETAKKVKELGFKKAGLLATTGTIVSG--VYE-FSKYGVEIMTPVMRGIGR---LLKTAKILEE--KVPLIDPMDVEV

   DYVLHQAALG-----NDP--NATNI------DGFLNMLIAARDAKVQSFTYAASSSTKYVNELYAD-SRCYGFSTIGLRYFN-------VQANLLAAT

HVPPTVLVWFR--------------NDL-----HD--HEPLHRALKSGLAITAVYCY-QSVQNLAESLQKVG-----NKLLVTTG-LPEQVIPQI-----KQINAKTIYYHR--------------------------------------------------------------------------------------LVKQLTI---------------------------TLCH----------------SKFSPWLALGCLSPRFIYQEVKRYESNDSTHWLIFELLWRFF

  RKVVAFQTR----------------PH-----RAHEYLIRLGLELADGVLVHPIKKPPTEVIVEAYQ---QERVAFFGLATPMR-EAVFHALVRKNFG---THFLVGR-AVFHCG--------------------CPEG-------------------------------------------------------------------------------------------REKRT

   ASVGLYIPG---------GSAP-LF------STVL-LATPASIAGCKKVVLCSPPPIADEILYAAQ------GVQDVFNV--GAQIAALA--GTSVP----VDKIFGP------------------------------------------------------------------------------------AFVAKRQVSQRL---------RVA-RLIVTK--------DLAQCVEISNQYGPEHLI----ESAGDYASGT--------------------SSLG

 QQLVDKHSTGGV------------VDS-----PLITASILSKKLVEGLSALVVDVKQEQARELAKTLVGGASLGLRVAAALTAM---------------------------PLGPPDLRDLVTTLGGA----------------------------------------------------RVAAAL------------------LG-----ERMAQ

  GKCAIITG-----------------A------GIGKEIAITFA--AGASVVVSDI--NADAANHVVDEIQQLGGQAFACRCD-SE---LLADFAISKLG-KVDILVNNA-------------------GGGVIITSM-MTS-AHLVRN------AF----------------------------------------------D-LG--EKNRVN------APG-------------AI-RRL-----QP

  AKAIIVLST--------------SG--------TTRLVSKY-R--PNCPIILVTRCPRAARFSHLY-------RGVFPFVFEEPVDVEARINFGIEKAKGDTYVSIQ-HS-------------------------------------------------------------NTLQVSTV

  GSTCAVFG----------------LG------GAGLSVIMGCKAAGAARIIGVDI---NKDKFAKAK---EVGA-TECVNPQKK----PIQEVLTEMSNG-VDFSFEVIG------------------AYGV--------SQNLS-----------------------------------------------------MN--PMLLLS-GRTWKGA-----IF-----------------V---VADF

  DRVVAFQTRN-------------PMH------RAHRELTVRAAREANAKVLIHPVVTRVRVYQEIIK---PNGIAFLSLLPLAMRMAVWHA-IRKNYG---SHFIVG--PFRTYL--IALLSTFLQFGGGRY-----NNKTE---LIQ------IG------------------------------------------------------GSGLI

  GHKVLVCGA-------------------------GPIGVT---VAGAAQVVVTDL---SATRLSKAKEIG----ADLVLQISKESP-QEIARKVEGQLGCKPEVTIECTG-------------------GGTVL--------SET---------------------------------------------------VPLLHAAIR----EVDIKGV---FR

  GKVALVTG-----------------R------GIGREMAE-LG--RGCKVIVNYA-NSTESAEEVVA-IKKNGSDAACVKA--VV-IV-MFEEAVKIFG-KLDIVCSN----TRG-FFVAREAYKHL--IGGR---------ETFAR-------AI-----------------------------------------------DMA--DKKIT-VV---AP---------------GI-AA--RR--LP

   MHVVYPGS-------------FDPLT-----NGHLDVIQRASRLFEKVTVAVLENFSAEERLAIIR-TAHLANVEAATFSG------LLVDFVRRVG---AQAIVK--------------------------------------------------------------------------------------------------------------------GLRAVSDYEYELQMAHLNRQLYPGLE

  TPLVVL------------------SG--------GIDSSGVAACAH-LDTVSMGTDTSN--EFREAR-VDHLRTRHREITIPLLAQLTALYRALD---GPERRILT---YGA-----------------------GMMATFD-LN-------------------------------MSPVSTL-------------------------------RE----LL-------KRR-KW

   MKLYMSVDME--PDDTFVYERGRMT------EEANYCIAEAFNSGCTEVLVNDMNNL--MVEKLHP-------EADLISGD--SM-----VEGLD---DTFRGALFLG-----------------------------------------------------------------------------------HFGELG-----------------------------------------------------LNAYVAGYYDVPVLM------AGDDRA-AKEAEELIP

  RTLIDIGSG-------------------------TVYQLLSACSHFEDITMTDFLEVNRQELGRWLQ---RQARVKRVLPI---DV----QPLGGSPAPLPADALVSAF-------------------PGGHL---------SEEVR-----------------------GVFFAWAQKV

  GKVALTTG-----------------R------GIGRGIAE-LG--RGASVVVNYG-SSSKAAEEVVA-LKKLGAQGVAIQADISKPVVALFDKAVSHFG-GLDFVMSN------------------G--------AAVPNHAGFAFAV-----------------------------------------------------CGAKG-------NCI---AP-------------ENS-----DEKRI

 EKKVLLTGF--FGG---ET-----PTVFY----KSLAVLREAIKKHQPDIIICVGQA-VCNHLFYGLM-ISRHHIRGGFIHIPY-------TKALKIAAV----------------------------HEDD

  HKVKILVDS----VV----KTSQPSV------EDFKKRYLKYKEEDYDVVLVLTLSSTYNSAVLASK---EVDIPVYVVDTLLASG--IP-LPARVARELE---------------------------------------------------------------------------------------------GATIEEVLKKLDERK----IPYRK-----------------------------KKAIALIEKLRED-------LRV------VELLNTLRKSYE

  ASIAVCPGS--------------DPVT-----YGHLDIIKRGAHIFEQVYVCVLN-FSVEERCELLR-TKDIPNITVETSQ-------LLIDYARRK---NAKAILR-GL----------------------DF--------------------------------------------------------------GTSVNR----------------------------------------VLDESIE

   GAGVVIAPW------------NFPV------AIFTGMIVGPVAVGNT-VIAKPAEDAVVVGAKVFE-FHGFPVVNFLPGVG---------GAYL---HPRIRFINF---------------------------------------------------------------------------------------EVKIYEAAGRL----WF-------------TGGKNAYEPVLERVLKRAERLS----------------VSAEQERKVLS----GGKR--YFI

  SPVVVVTG-----------------R------GIGKAIASL------CKVLVNYA-RSAKAAEEVSKQIEAYGGQAITFGGD-KE--VEMMKTAIDAWGTIDVVVNNAG-------------------RKGRI----LIQANAGVIG-------AR----------------------------------------------------EGANVNVV----CPG---------FIA-TG

 YNKITVVGC----------------D--AV-----GMADAISVLKDLADEVALVDMEDKLKGEMMDLE-SLFLHTKIVSG-------------KDYSVSAGSKLVVITAGAR-------------------------------SR----------------L-------------------------------VNIFK-KQDWKL-----PM---NLDSAR

  GSVCAVFG----------------LG------GVGLAVIMGCKVAGASRIIGVDI---NKDKFARAKEF---GA-TECINPQFSK---PIQEVLIEMTDGGVDYSFECIG------------------GWGV---------GEEI-----------------------------------------------------ATR-PFQLVT-GRTWKGT-----AF-----------------V--PVSEY

  STAIVT----------------------------VKHGMGSALR-LSHTVACHFK--QKDELEAFAE---TYP-QLKPMSE----EPAELIEAVTSAYGQVDVLVS-ND-------------------RKIIFITSATLST----GAT-----NA-----------------------------------------------EL-GEY---VFAIG--NY-YF-------------PTEPWKT-----TQ

   GKTVLLG----------------AG------GASTAIGAQGA-EGLKEIKLFNRRDFFDKALAFAQ-NENTDCVVTVTDLA---------QAFAEALA-SADILTNGT--------------------GLL-----------PH---------------------------------------------------LLQQAQQAG---------GLL

TPGSTCAVFG----------------LG------CVGLSAIIGCKIAGASRIIAIDI--NGEKFPKAKA----LGA-TDCLNPR------PVQDVITELTAGGVDYSLDCA-------------------GWGSC---------VDEM----------------------------------------------------TIP-TVDVIL-GRSINGT-----FF-----------------V--PNSDY

   GAIALSV----------------GG------GLLCGVVQGLQEWGDVPVIAMETFGAHSFHAAAL--FQ--EHPIFSEVISAVAAALAAVHVIQKLQTPLPSLVVI

   LRGFIIGR------------QP--FH-----KGHLEVIKKIAEE-VDEIIIGIAGERILMITQSLK---DYDLTYYPIPI-KDIWV-YVESLT--PP---FDIVYS----------------------------------------------------------------GN-------------------------VLFEERG

  GSSVVVIGI------------GAVGL------MGIAGAKLR----GAGRIIGVGSRPCVEAAKFYG--------ATDILNYK------HIEDQVMKLTNGKGVDRVIAG---------------------PG-----------------------------------------II-----------------------LIP-RVWGC-GMAH---------GLC--------G--RLRAERL

  GSTCAVFG----------------LG------AVGLAAVMGCHSAGAKRIIAVDL---NPDKFEKAK---VF---TDFVNPNHSE---PISQVLSKMTNGGVDFSLECV-------------------GWGVS-------DLHDV-----------------------------------------------------ATR-PIQLIA-GRTWKGS-----MF-----------------V---VKAY

 DGRVVLVTGA-------------------------GGLGRAY-A---FALVVVNDL-KGSSAADKV-EEIRRRGGKAVANYDS-VEAGEKLVKTALDTFGRIDVVVNNAG-------------------NYGRI----I----AGLLG-------VI----------------------------------------------------EGR----------NTI-----AP--TET--DL----------LCHE

  MKKVITYGT---------------FDLLH----GHIKLLERAKQL-GDYLVVAISTDSYEHRKLILE--TIRYV-DEVIPEKNWE---QKKQDIIDHN--IDVFVMG------------------------------------------------------------------DWEFDFL

   MRGLLVGR--------------QPFH-----RGHLQVIKSILEEVDELIICIGSAFTAGERVMMLT-I-PASRYYIIPVQD--I-----VGHIKMTPP-FDRVYSGN----------------------GYEV

  GKKGLIVG----------------AN-----KSIAYGIAQSCFNQGATLAFTYL----NESLEKRVRPAQELNSPYVYELDVS---------FLYNSVKGSLDFIVHS---------------------NGAS----TK---AALES-----------------------------------------------------LAVDLG--KHIRVN------SA--------------PI

EP-GVCAGILAW------------NYPF------MIAAWKCAPALACGNA-VVFKPSPMTPVTGVILAE-FHEVPLVNVVQGG-A------G-SLL----HPNVAKVSF---------------------------------------------------------------------------------------PTGK-ME-----------------------ELGGPQLDKVLGFVAQAKKEGARVLC

REPGVVAAITPF------------NYPL------FDAVNKITYSFIYGN-AVVVKPSISDPLPAAMAVK-LDAGFPAIALLNLPG--------EKI----DDRVAAVSF---------------------------------------------------------------------------------------ERVV--GV-----------GGDCDAIKLV---------LVEEVAKRLSSLR

 SRVLIVG----------------------------GYIGKRIVNASIPTYVLFR-----P--EVVDKV-LLYFKAKLIEASLD----------HLVDALKQVDVVISALAYT-VD-DVGTYTIKSIDD-----------------------------------------------------------------------------------NKTMYIR-------------------------------------------YISSQDFLADMKDK-SYEEKIVRCHLYQI

  LRVLVAVK-RV-GVV---TDHS--MN-------FCEIAVEEAVRLK-EVIAVSCGPAQCQETIRTAL----MGADRGIHVEV-LQVARVLAKL----KEKVDLVLLG--K--AS--QVT--LE-GDK--------EIDG----------------------------GLE------LP-----------SKLS

  ERVLYLG---------------------------SGTTVS-LA--IVIIYAVEY----SAKPFEKLL-VRERNNIIPLLFD-------SKPWKYSGIVEKVDLIYQDI-----------------KE-KGEVV------EPEEVFK-----------LK------------------------------------------MEGDF----KIVKHGSMP-YHRD

  GSTCAVFG----------------LG------GVGFSAIVGCKAAGASRIIGVGT---HKDKFPKAI---ELGA-TECLNPKDK----PIYEVICEKTNGGVDYAVECA---------------------------------NER-----------------------------------------------------PLDPLLLL---GRSLKGSV-----------KA---RSI

   KRAIYPGT-------------FDPT------NGHIDIVTRATQMFDHVILAIAASFTLERVALAQQ-TAHLGNVEVVGFSD------LMANFARNQH---ATVLIR-GLR---------------------------------------------AVA-------------------------------------MNRHL------------------FIS----------EVAQGDVHQA

 TAPVALVTG------------------------RLGSSIAEALHAEGYTVCLHYH------RSAADAS-AATLNSAITVQADLSN-----CSALVDACYMGRCDVLVNN------------------GT--YSI----TS---MA------------------------EAL-------------------------------------ELARVNGV---PG

  MRVLLSVC----------------GT-----RGDVEIGVALADRLKQTRMCA---------PPAAEE-LAEVGVPHVPVG--MTVE--MQ-FDVPGAAEGCAAVVAVG---------------------GLPF--LASP-WEERA----------------------------------------IGLPPVE-------------------ERP--LQ-------SSGRGIADAAKVAVEAIRAQGRRVI-RRVA

 VPYGVLL-S-------------------------GLSIISAITK--A-LHSFAVGLPGSLK-AQEVAN---HLGTVHHEIHFTV-TPMYLMSRKIKAMG--IKMVLSGE-GS---------------------------VRK--ALH------------MY------------------------------------RANK----------VPFDKFLDVA-----------MEKH-LRE

  SRVVAFQTR-------------NPMH------RAHRELTVRAARSRQANVLIHPVVTRVRAYQALLP-YPN--GMAVLGLLGLAMEAIWHII--NHGA---THFIVG-----------------------------------YG-------------------------DAQ---------------EVVKILEIKGF-DDP-------KALVVDF---------------RSIVHEIILVLESQGF

 MKIVLAY--S---------------G---------GLDTSIILKWLKRVIAFTADI-----EVEEAREKALRTGAKAIALDLKV-IARPLIAKHLVRIAE-EAIAHG----AT---------------------G-----------------------------------KG--------------------------ELTAYA----------------GR--YSMPK-SPAA------EIGGRHGV

 VMKKILYPTD----------------FSET---EIALKHVKAFK----EEVILLHV-EAKNKMENIKK-LEDVGFKVKDIIVVGIPH-EEIVKIA-DEG----VDIIIMGS-------------------------------------------------NLK-------LLG------------------------NVKKSN--------------------KRK

  GKRILVSG----------------IT-----SSIAFHIARVAQE-QGAQLVLTGF-DRLRLIQRITD----LPAKAPLLEL-DVQ-LASLAGRVTEAIGNKLDGVVHSI-----------------------------FFDA---------------------------------------------------YSYA-RFVAREAG----YGVR-------LVA-LGEE-------LEEGWDQRAGWNMKDATPV

   GVCGQIIPW------------NFPL------LMQAWKLGPALATGNV-VVMKVAEQTPLTALYVAN-IKGFPVVNIVPGFG---------AAIA---HEDVDKVAF---------------------------------------------------------------------------------------EIGRQVAG----------------------LGGKS-YDEFVERSVARAKSRV-----------------VD--ETQFKKIL

   GVCGQIIPW------------NFPL------LMFTWKIAPALCCGNT-VVIKPAEQTPLSALYMGA-IKGFPVVNILPGYGP--------AAIA---HIGIDKIAF---------------------------------------------------------------------------------------EVGK-QE-GR--------------------LGGKSIYEEFVKRSVERAKRRI----------------IDKKQYNKI------GGKG--FFI

   GVCGQIIPW------------NFPL------LMFLWKIGPALSCGNT-VVVKPAEQTPLTALHMGS-IKGFPVVNIVPGYG---------AAIS---HMDVDKVAF---------------------------------------------------------------------------------------EVGKKEAAGK--------------------LGGKS

   GVCGLIFPW------------NAPM------ILLACKIGPALCCGNT-VIVKPAEQTPLTALHVAS-IKGFPVVNIVPGYGP--------AAI----HMDVDKVAFT--------------------------------------------------------------------------------------EVGKQEAA----------------------LGAKNIYDEFVQRSVERAKKY------------------IN--KAQHNKIM

  GSTCAVFG----------------LG------GVGLSAVMGCKAAGAARIIAVDI---NKDKFAKAK---ELGA-TECINPQKK----PIQEVLKEMTDGGVDFSFEVIV-------------------------------SQNL-----------------------------------------------------IN--PMLLLT---TWKGA----VY------------------I---VADF

  GKRILVTG----------------AS------KLSYGIAQAMHREGAELAFTYQNDKLKGRVEEFAA---QL-GSDIVLQCDVAE-IDT---MFAELWPKFDGFVHS---------------------PGSA----------ANVR------------------------------------------------------MANAMG-----EGVR

 HNKITVVGV------------------------AVGMACAISILKELADEIALVDMEDKLKGEMMDLQ-SLFLRTKIVSGK-------------DYNVTANSRLVVIT----------------------NCKL-----------TY-----------------------------------------------------VAWKI---PKNVI--NLDSAR------TSWAIGLSVADLAESIMKNLRRVH

  AAALIVLTE--------------SGR--------AHQVAR-----PRAPIIAVTRNHQTARQAHLY------R-GIFPVVCKPVQDVDLRVNLAMNVGKGDVVIVLTGFT-------------------------------------------------------------NTMRVVPVP

  TSLHLFGL----------------SDG------HIHHLYAL-LAEVKRVYIHGFL-QTAPQYIKELQ-IKEYGVGEIATLSG-YYSM-KAYRAMVPVAT--NDAIIFYNF--------------------------------------------------------------------------------------ISNTFTNE-----KHPKH-RI-ALLNYANPAVEAVDECLGKVVDAILAKGGIAI----MLDGLPQ

   DAVVHMCAFLAVESVRDP--YYNNV------VGILRLLQAMLLHKCDKIIFSSSAAIKLIAERMIR-AEAYGIKGICLRYFNA-------SAHILALD

  PLIGLLFS---TADIEYPT---PY--PA---NQNSAPLAAYLIRHYGERVVFIGSDYYPRESNHVMRHYRQHGGTVEEIYIPL---------AVERIYQ--RPPIASL-VV-------------------------IDTP-----AS-------------CHG----------------------------ENAT------------------------------AWAEA----SRLS

  LGPVAVFGA-------------SNFP------LAFGGDTASALAAGCPVIVKGHT-AHPGTSQIVAECIEQALIFTLLQGNQR--------GQAL--VHPEIKAVGFT--------------------------------------------------------------------------------------GGLFNLAHERP-------IE-VVC------EE----DYPQVSQLIPRLEEIAGRLV---PTGV---------EVGY------------AMVH

   DTLIPNAGIW-----AFDE-VFINV------KGYIHAVKACLPAL-GNVIFTISNAAKHAIVGLVR-AFELAVRVNGVGSGG-S------EYTGAYVF

  GTTVLVIGA-------------------------GPIGLVS-A---AKFVVCTAR---SPRRLEVAKNC----GADVTLVVDKEEE---IIERIRSAIGD-PNVTIDCSG-------------------GGTL---------QMV-----------------------------------------------------VP-LVNACA--EIDIK-------VF

  SKVVAFQTR--------------NPMHRA----HEELCRMAMESLDADGVVVHMLLARDAAIRTMAE---FPPNTVMVTGYGFDMEAVLHYF--NMGA----THFII-----------------------------------GAFD--------------------------------------------------AQTIFDD

  MRVLLATC-GS--------------------RGDTEPLVALAVRVRDVRMCA---------PPDCAE-LAEVGVPHVPVG--EAIA---QFDEIPAAAEGCAAVVTTGLFH-----------------------VPSYPP--RNN----------------------------------------IGLPPVE-------------------DHP--LQ----------------------PLSP------LGF-------GAPADAVRVAIDAIRGRRV

EPGVVLVIGAW-------------NYP-------FNLIQPMVGAVAAGNAVILKPSEV-SGHMADLLAT-IPQYMYLVVKGGV------------TTELLERFDHIMYT-----------------AAK---LELCVAP-----------------------------DY--------------------------------------------AHVDVDP-VC--------LEEAIQFINQREK--PLALY-VI------------TVPTLP

FTDRVVLITG--------------------------SGLGRATAR---LAKLSLVDV---SSEGLEASKAVLETAAEVLTTVA--SDEVE-YVTATTERFGRIDGFFNNAGVV-----------------------ASVG--AA--GVVG-----RN-----------------------------------------------------EY-INAI-----APG-------SM-------RY------EAP

 TVP-VALVTG-------------RLGR------SIAEGLHAEGY------AVCLHYHRSAAEANALSA-NARRPNSAITVQADLSN---C-AELVAACYT-GRCDVLVN-------------------HR-------------RSAALAP

   GNCHIFVDE------------SADL------KKAVPVIINATQRPA--EKLLVHEKIAKEFLPVIV-LRKHGVEVAIKVVKNVD-AIEIKK--Y--------SESILTA-----GQ-IGI-----STQR-----------------------------------------------------------------------------FHAR---GP

EGKRVALVPTM-------------N--LH-----DGHMKLVDEAKARADVVVVSIFV-RTLQEDCEKLN-----KVDLVFAP----GVSTIVSKLFNLVQ---PDIACFGE--------------------DIEI-LSSRN---------------------------------------------------------------------------------------IAPGLYKVL

   QEVYNLAAQSFGAS-NQP--TGVDG------LGVTHLLEAIRFSPETRFYQASTSEAKLYGHWITVNYESFGLHASSGILFN-------VEAMWLMLQ

SNTRVALVTG-----------------KG------IGFAIVRDLCRQFAGDVVLTAR--DVARGQAAVK-LQEGLSPRFHQLD-IDL------RALCDFLEYGLDVLVNNA--------------------PQGR--STVRAL-----------------------------------------------------------------------------------------------------------NECSLQQKFKSETIELVGLMNKFVEDTK-DSTYGVTKIGVS

  MPIEIITDSG----VHW--TAQ---PS----PLAMKELFLPYAKENR-PCLYIAFSSTYQTAMAVRS-LDEYPFRLTIIDSCASLGVMKAV-------ELAK-----------------------TPYN------MEHI------------------------------NL--LI-----------QTIGFLS

FQWFGSNESGAEFG-------GVEGYIW--------DPNTIDTLISKGMNIFRVPFMMER-LADLIATVNITQKGAYAVVDPHN-------------------------------------------------------YYIISSPTDNE------------LV-------------------HQY--GS---------GTS-ATC--VSS--------------GGADNVCETAITGMLDYMAQNTDWTGA-----------------------AYQQ-ILPILTPYL

  GKVALLSG--HE-----EIFTSP--T------DKIFECAMQVD-GGE-GVLLIIKNYDILNFETATE-LHDSGVKVTTVVIDNTVLEKLVG-------AA-AE-----------------------CAERKLERNL---------------TLLKVTLADAP

  MRVLITGC---------------GSR------GDTEPLVALAARLRDARMCL---------PPDYVE-CAEVGVPMVPVG-EVV-------FDVPAAIEGCDAVVTTG---------------------GIPY--PSE-SQA-----------------DM------------------------GLPPVE-H---YG--------------DQ

  TTHLVWFR---------------QDL-----H---NLALAAACRNARVLALYIATP-INAQLNGLQI-LAEKGIPLLFREVDDFV---ASVEIVQ-VCAENSVHLFYNY-----VN------VERAL--NVVC--SV----------PGA-------------------PSI--------------------PVEE----------------------------------------------DFP-----SRLSASLATGGLSPRQCLHRLLAEQGA--GSVWLNELIWRFY

  ELKVLDLY----------------GV--------GIQSAIFYNKYCPRQYSLLEKRSSYKFLNAKFEGS-----PLQILKRD------YDWTYLIRIFVPEKFLTVAN--------------------GKVKM---------AR---------------KLLAR----KL

 FLWGVATSAY---------TQED-DHY------HRYEEDIALMQSLGVGVYRFSVAWPR-LAFYDRLVDLLAAGITPFLTLYHWD-------------------------------------------------------------------------------------------------------------------------------------------GWRSRETAFAFAEYAEAVARALAPFFA-AAHHLLL--GHG---------NFAP-YHNRYFLDPILGR

 FLFGAATSAY---------WNED-DSYH------MYAEDVRLLKEMGMDAYRFSISWPR-VEYYNKLI-LLENGIEPYITIFHWD-------------------------------------------------------------------------------------------------------------------------------------------GFLDERIIKDYTDFAKVCFEKFGKNWL

DY-DTAAEIDATFPVDGGPEA---LDAL------RRIRQETEDAVRGGATHVILTD-AIPAILATGAVH---RTFTSLNVRTAE-------------------------------EA----HFP--------------------------------------------------------------------YNE-GAS---IK-------------------KT---VVNLFTFLAEEVREILAGLG----VIGRT---AQVDPG

  PFVEHIHLD--WAERKALL--T--VK------QRAWQTLKWQIANGIQHVRTHVDVTALKAMLEVKQ-V-APWIDLQIVAFPQEG-------------------------------------------------------------------------------------------------------------------------------------ALL--FEFTREYGVESLHKTFALAQKYDRLID

RNVALITG--------------------------------GQDGSYLA-VHGIVR------RS--FNT----EHLMKLHYG----TDS----LVKIINEVKPTEIYNLGAQSH-------------------FYQSTSYGK--------------------------PFY--K----------------------------IVVNFREAY--AVNGILF--N--------------N-TRKISRS

 FTFGAATSAY---------AWNE-NSYH------MYKTDVRLLKEMGMDAYRFSISWPR-IKYYRNLINLLENGIEPYVTIFHWD----------------------------------------------------------------------------------------VP------------------HKS-EDYTYFAKVCFDNF------------FAPGRCDCA

   GPLLVWHR--------------GDL-----HD--HPALLEALARGPVVGLVVLD--FLENVRALRE-YRARGGALWVLEGL--PW-----EKVPEAARRKAKAVYALT---------------------------------------------------------------------------------------VREALP----------------------------HLLP----DRL--------GSRLSPYFALGVLSPRLAAWEAERRGGEG-ARKWVAELLWRFS

  AAAIIVLT----------------TT--------GR-SAQLLSY-PRAAVIAVTR---SAQAARQVH---LCRGVFPLLY-EPPDDVDRRVQFGIESLRVDLVIVVTGYT-------------------------------------------------------------NIMRVLSI

 KNNVVIVATGVA---------S-ITEL------LSLARQVNDLVKKSVNGVVITHGTDTMEETAFFLN---HTDKPIVLVGSM----------NLYSAVA------------------------LA--NEAK-ARD----------QWG---YWFRSS-------------------TN-----NIEKIALPG--------------------------------------------------------------------------------GSM-----PEVRKLHDE

 FMWGTATAAY---------AYQE-DSY------HRYEEDIRLMKELGIRTYRFSVSWPR-LDYYHRVVDLNDNGIEPFCTLYHWD------NEP------------------------SDWFL--------------SV---------AGFL---------------EE--------------------------------------------------EV----GARISYMQQHLVQVHRTIHDGLHVK

   GLVLAISPF------------NYPV------NLAGSKIAPALIAGNV-IAFKPPTQGSISGLLLAE-FAGLPVFNTITG-G---------YIVE---HQAVNFINF---------------------------------------------------------------------------------------ERIG-KGM-------------------------------MESVADELVEKIR----------------SADYVEGLINDAND

   DEVYNLAAQS-----EIPTA--VVA------TGALRLLEAVRH-RTVKYYQAGSSEMKCAAHWYTVNYEAYGLFACNGILFN-------VEAMWLMLQ

HPHVMGILNVTPD-------DGGTH-SL------IDAVKHANLMINAGATIIDVGGELQRVIPVVEAIA--QRFEVWISVDT------SLGALEAA--TG----LPVC------------------------------------------------------PKYDDVF---------------GFGFG-------------RKSMIGQLL

 MKIGIFDS-----GVLGD---I--CNS-VF---GVIEPGVKEALKKSRKKIGVIGTPATVKS--GAYQRLEEGGADVFAKACPL--------VYLKEFKG---AEVVDSSEA--------------GS---SSL--------KLI

 FLWGSATASY---------AAED-DHY------HRWREDVALMAELGLGAYRFSLAWPR-LDFYRRLADLLAKGIQPVATLYHWD-------------------------------------------------------------------------------------------------------------------------------------------GWPERATAERFAEYAAIAADALGKTWT

 ETLGIIG--------------------------------GRVGQAVANVLFYDPY-------LSD--GIERALGLQRVST--------------LQDLLFHSCVTLHCG-NT-----------------RGAALDV---------SEPFS-----FSQG-----------------------------------------------LKAPNLICTPHA-------WYSEQASIEMREEAAREIRRAI--CVNKD

 FKWGVATAAY---------YNED-DSYH------RVEEDVQLLKDLGVKVYRFSISWPR-LDYYHRLVDLLANGIEPFCTLYHWD-------------------------------------------------------------------------------------------------------------------------------------------GWGSRITIDAFAEYAELMFKELG-WIT

   DAAILVVS-----------KGEAGMSVE----QTREHIILAKTMGLDQLIVAVKMDRYKEIVDQVSKMR-FNTKVRFVPVVAP------IT-LEEYLD-EL

   NVAVISGGGHE-----DVFASP--S------DAVLTAIQAVT--GEAGCLLIVKNYDRLNFGLAAE-ARRLGYNVEMLIVGGTILHKIAG--LRE-------------------SNW---PT--PVPPR-----------------LV-----AGIVLV-----------------LQPALTS---------------QPKN

  RVFAIGNP------TPEQM----------------PGGLNSVRVVQ-AGYMGAI---GDDPRGQVLKECDKEGLATRFMV-PGQ-------RLPEDWTT--IFYAT---------------------AITNILFGNEE-------HLAGA--LRL---------------------GKTQCIMCGNACQDVHVGF

   DKILIIGGG------------IGVP-------PLYELAKQLEKTGCQMTILLGFASV-KILENEFS---NLKNVTLKIA-D------HV-GMLMNEIDFEVDALYTC----------------------LERSME-GA-----EHDKE----------DESH------DGVF-------------------------------GKQ---SL

   DGLVNNAGI-----RFRKVV--INL------TGVFIGMKTVIPAMGGSIVNISSAAGKWGVRGLSK-AVELGIRVNSVHPG--------AGAVVKLLS

   GRVLEVGF------------------------GMAIAASRVQQAPIKEHWIIECNDGFQRLQNWAL---KQPHKVVPLKGL----WEE---VALP--GHFDGILYD----------------------PGGI--------MK--ITA---------EET---------------------------------------A-LLGFQR-------CTEVM

  GDKVLDLG--------------------------GS--GVLAIALGGKALGVDI----DPMVLPQAE-AKRNVRPRFLEGS---------LEAALPFG-PFDLLVAN---------------------GGRLTGIL-----KDRAP-----------RE----------------------------------------AMAGAGF----RPLEEA

 VHINREPFGP-GTL-------PPSMSN------AVGITEALLAAEQGVKNITVGYGEDALRCLEEQTN---KNDVFVTTVFHQWM------------------------------------TTIAALAGAT------------------------------------------------------VKTPHE--------IP--TKE

AEKVLVTG--------------------------------GYIGSHTV-PVVIDN-----------RGGSLRRVQVEFEEM------LDQ---LQLFKKYSFMAVIHFAGLK---------------HG--NLVFSSATGNGCTNSKF-----------E-------------------------------------------IDLCQAD-NAVLLRY---FN----------GIP----PYVSQ

   DAVIVLLGTRND--L---SPTTVMS------EGARNIVAAMKAHGVDKVVACTSAF-HIRMHKVLR---ESGLKYVAVMPHIKH-----GHFMLRCLT---------------------------------------------------------------------------------------------------------------GHSTY

  CP-AAVITG-------------RIGH------SIAVRLHQQGF------RVVVHYRHSEGAAQRLVA-NAARAGSAVLCKGDLSDC---CEDIIDCSFR-GRCDVLVNS----------------NL--------------RAAALLAP---------------------RV---------------------------------------TGTTL

                    GL------QGS---GKTTTAAKLALYYK--PLLVAADTQR-PAAREQLRLGEKVGVPVLEVM-ESPESI---RRRVEEKARLARDLILVD---------------------------RLQ--DEPLM-------------------------------------------------EVGP-----------EVLLVL------------EAL---LT--KLDVS

 KLVNIAVSGA---------------GM-------ISNHLLFKLAVFQPIALKLLGSERSFQALEGVAM-LEDSLREVSIGID----------YEVFE---DV-DWALLI---------------------NFHALTRDE-IWGNH---------------------TQV---------------------------------------------------------SSAASTAVSIADAIKSLVTP---STGVYT--NPYGI

 VKAIADIVINH--PYADGTGNPDIDHLNLR--QKELVEWLNWLKAIGFDGWRFDFAKGYSADVAKIYI----EPSFAVAEIWT-----MWP------------------------------------------------------------------------------------------------------------------------------------------------------------------YAYILTHPGTPCI---DHFFDW---GLKEEIDRLVSV

  GKRAFIAG----------------AD-----NGYGWAVAKSLAAAGAE-ILVGTWVPALNIFETSLR----MEIKKVYPLDAV-FTVQE---AAECVRFGSIDILVHS--------------------PGGA--TYIASSS----AL-----RVL-----------------------------------------------------FEA-VNTIS--GP-------------------GSR

  KKVGVIFGK-------------YPVH------TGHIN-IYEAFSKVDELHVIVCSD--VQDRLRWQQ---YQQIFIHHLVED-SYP----SEAVKTLFHFEPSIVFS--------------------------SE----------------------------------------------------------------PYEK------EVSLVDPD-NVSAT-SPSYLDRYNQ-------VLNEEEISE

  GKKVALLGD---------------PD-------EIIALSKFIIELGAIPKYVVTGT-PGMKFQKEID-LAEAGIESKVKGD-------F--FDVHQWINEGVDLLISFG-KGAI------V--IT-ILDK----------------------ER

   DTVGIPLS---------------G-------LDSSLVTALASRHFKKLNTYSIGSNEFEFSQQVAD---AL-GTHHQMKIL--SGLFNVYRQAQG----QVSCMLTGY------------------------------------LF---------------NPN-------------------------------GEFAT-------------PFSH-SLI-------KIF--NI

 SRILLIG----------------------------GYIGRHVAKASL-TFLLV------RES--AKA--FKASGANIVHGSID----------HLVEAVKNVDVVISTVGYT-VK-DIGTFTIKAVDDP---------------------------------------------------------------------------------LNKTLYLRL------------------------------------------YVPEEEVLKLIADT-PFPANISIAISHSI

GQLQVAEVSTLYDLDGVN--S--LEDAL------TNLVKTAIATVQAGAEILVLTFIP--PLLAVGAVH---RLKASLIVDTA

LTGKVALVSG--------------------------RGMGASHVRAMVAKVVFGDI-------LDEEGK-AAELAARYVHLDVTQ-AQWK-----AVDTAVGLHVLVNNA----------------AG--RGSIIN--EGTAT--------------------------FAV--------------------------LTKSTALELG-----RVNSIH-GLV------------TDWV--PE

 FLWGVATASY---------PLAD-DHYN------RWKEDIEIIEKLGVKAYRFSISWPR-LDFYNRIIDLLEKGITPFVTIYHWD-------------------------------------------------------------------------------------------------------------------------------------------GWANREIADWFAEYSRVLFENFGKNWI

 ARKIGIIGL--------------------------GNVGAAVAHGLVADDYVFIDA--NEAKVKADQI-FQDAMGNIVIN--------------DWAALADADVVISTLGNI---SMVQSVGTNLKE--HKVIGTGT------------------------------------------------------------------------------LLDTAR------------LNGK

  EIVADAAA--------------------------PGGKTSYLAQLR-GVIYAFDV---DENRLRETR----VLNVILFHSS----------LHIGEL-VEFDKILLD-PC------------------PGGI-LPLKY-EPAL----SEE------KNARR

 TRLAIADLG----------------SS------PNALFAVTELIKTV-YQIFLNDLPGNFNAIFRSLP--NDVDCFINGVPG--SFY-----RLFP----NTLHFIHSS----------------------------------YSLM------------------------WLSQVPIGIESNKGN------QEDHLFL

 LANVVILATGQIA--------SIT-DL------LKLGKRVAELADSNVDGIVITHGTDTLEETAYFLD---NTDKPIVVVGSM-----------LYNAV--------------------------ASNKD---GRDV-----------GP--YWFRLP-------------------TV-----DIKQISSL-----------------------------------------------------------------------VSSRLTPA-QTLRKTG----------VAHDL

 ARPIVLVGKGL-FDSGGIST--DAEGRL------VLCDVLTYVERFEPEAVIDVATTG-AITAGCFLS----RKYNWAHLDIAW-------VALLAQFLL

   DTVIHFAGLKA-ESVQKP--YDNNV------NGTLRLISAMRAANVKNFIFSSAATVKLMVEQILT-QKAQPWSIALLRYFN--------AGHVVAME

QDEVIIAVGPA------------LAQT--------PHKSILREVIAGIE-----------------------EEGIKARIRCFKSS-DVAFVAVEGNRLSGSGISIGIQSKG--------------------------------------------------------------TTVIH---QQGLPP-------------LS----------PVP-------LNDQ

   TVYVAG---------------------------GPVGLAAAASARVVIVGDL--------NPARLA-AKAQGFEIADLS---LD-------PLHEQIAPEVDCAVDAVG-------------------VAGK----------------------------------------IG----IP------YVTEDLS--IRFGLGWAKS------HS-----PV

   DAIVHFAAESH----AGA--FTTNV------QGTQTLLQCAVDAGVGRVVHVSTDEVKAGSDLVAR-HRTYGLDVRITRCNN---------CIALVLA

 PFVVASVFVNPYH------------R--------DLERDRALLQEAGVDLLFAPGVE----------------------EY----QGVATVVARLFLLVQPQRAY--F----------------------VGVPTVREAPVL-RLIDNLE

  NLISLF----------------------------GA--GGLDLGFQRIICANEY-------DKSIWK-ESNHSAKLIKGDIS----------ISSDEFPKCDGIIGGPP----GKLFYEYIRIL--KKPIFFLAENV-----GMM---------------AQ-----------------------------------FIQEFDGYD-KEL--YLPPIP------------------------FKDV

  GKKFGLYG---------------DPD-------FVMGLTRFLL-LGCEPTVILSHN-ANKRWQKAMN-LDASPYGSEVFCDL-------FRSLMFTRQ---PDFMIG---TGAM------LVNAV-KL

YGKTVADIGT----------------GS--------GA-IG---V----AIVFATDSSKAVEIARKNAEVSD----RFFVRKG-------EFLEPFKEKFASIEMILSN----------------------SGKI---------DQVE-----------KK-------------------------------------------I-VS----DTVFLKD-SA

  GLVDVAVN-CAGI--RVIN--LIGTFN------VIRLVAGVMGQNEPQRGVIINTA-IVGMTLPIAR-LA--PIGIRVVTIAP-----AVQMVIENP

 FIFGVASSAYQ--------TIGR-DSFS------YWQKDIDVLDELNATGYRFSIAWSR-IDYYHGLISLIKKGITPFVTLFHWD-------------------------------------------------------------------------------------------------------------------------------------------GFLDPQIIDDFKDYADLCFEEFGKYWL

 KEGICLIDFS-L---FEKI-NLMV---RHL--LNSIKFNVKKAKTLGYTKIVLCIDHKVIDELKAYMP--------YIVMDIDKYE-DDHIAV-L---FEGHKILIIS--------------------NVKQWKK--------------------------------------------------------DKKD--------------------------------------------------------------------DREQAKVLLTE

  ERFIDVGT--------------------------PGLPGI-LS--RAHFTLLDS----LGKRVRFLR-QHKLENIEPVQSR--------V-EEFPS--PPFDGVISR-------------------------ALKGQ--MPE--DEI---------AL--------------------------------------------EEYQ----VESVVKLQGE

 GPIVDKHSTGG----DIATVDSI---------PLITASILAKKLAEGLDALVMDVKYELSEALAEAIVGANGAGVRTTALLTDMNQVLFDVT--LCVEMLKL-----KAAE-------------------VF---------------------QKGP-LP--TA

RDKGVLVLA---------------------------RGIGRAVADVLSAEVTICAR-------NEELLK---RSGHRYVVCDLRK-------LD-LFEKVKEVDILVLNAG--------------KEK--WGRIVA--VISPENSARMTG--------------------------------------------------F--LTLSFEVAPTVNC------PGW-------LL

    RVALAT--LRD-IA------DAIT-----PALLHEVIAILHHDLPRILVCGLNGTEEIDTIIPVLNLRAQGKLNGPLPA----------DTLFKYLD-N-DAVLA-YH-------DQGLPVLGF---RGVNTS---------DH--------------GTAL

GVQAIADIVINH--KYSDGTANLDIDHLNDR--QRELKEWLLWLKSLGFDAWRLDFARGYSPEMAKVYI----S-SLAVAEVW------MWP----------------------------------------------------------------------------------------------------------------------------------------------------------------QGYAYILTHPGIP--CI----YDHFNWGFKDQIAALVAI

 TLIMGILNVTPD-------SFSDG--SYN----DAAVRHAKEMRDEGAHIIDIGGEIKRVVPMIQAVS----VKLPISIDT-------------NDI-----ILDP----------------------------------------------------------------------------GIGFAK------------SFIGHVLD

 ARTVVLITG-----------------S------GIGL-LA---L---SFKVYATLRD--LKTQGRLWE---ACPSLETLQLD--RD---SVAAARERVTEGRVDVLVCNAG------------------RGSGR----LM---GLCEAV----LP--------------------------------------------------------FGVH-------IEC--------GPVAAQ

 FVFGTASSAF---------AFED-DEYH------RYKEDIGIMKDMNLDAYRFSISWPR-INYYNNLINVLANGMQPYVTLFHWDEPWGVSMNAYAYRCS-SGRLAAHY

 DKVILGL-S--------------------------GVDSSVTAMLLHNLTCVFVDNGLL--EAEQVLD-GDHFGLNIVHVPARFIRVFVEVFDEELK-LEDVKWLAQG---TIY----------------------VIE---AA-----------------KELF------------------------------------------------------KVSQAFTV-SLR

PDALILVAVGL--------------EKP------GNLGAVLRSADAAGAEAVLVAG-------GVDL------FSLRTLAASES-----------VLDWINLPVAIAVG--VSV--------LYEALRQR

GQLQVAEVSTLYDLDGV--NSLE--DAL------TNLVKTAIATVQAGAEILVLTDF--PPLLAVGAVH---RLKASLIVDTAQ

 HNIMVDAIVNH----FLT--SV-IDTDSDK--WEYLMSIFDQMAASHVSYIRLDAVGYGTFKLISRLR-GVKRGLEILIEVHSY---------------------------------------------------------QVE-----------------IASKVDRVY-----------------------------------------------TVLD-DIGSLK-VPDEDVDNLVNTIHANTHSQ-TGAAASN

TN--NVIFVA-------------GGIGL------DTSRELV-----RNLKNFVILDRV-ENPTALAELK---NPKVNITFHTY-DVT-SK---KLLKKIFD-KTVDILIAG-------------------GPGGI--GFNAAS-VSTNAK-----PI---------------YS---------------------------------------NGAIW

 VQVMGVLNVTDDS-----------LDL------DDAVKHGLAMAAAGAGIVDVGGETSRVIPVVKELA---QG-ITVSIDT-------------ND-------PWV--------------------------------------------------------------------------------------------------------------------MH---VAEVRADLLASVADAVAAGVDPAR

 IKVIADVVINHR--YFHPN-CC-ICHHKEW--QYWLWSYAAYLRSIGFDGWRFDYVKGYGAWVVRDWL----WGGWAVGEYW------------FDFVTF-------------------------------------------------------------------------------------------------------------------------------------------------------PAYAFILTYEGQP-----IF-YRDEEWLNKDKLINLIWI

   DIGVLVISAR-------G---EAGFERG----QTREHAVLARTQGINHLVVVIYKECVDKLSMFL----RVA-DVKYMPV--SAYTGQNV-SLLEYLD

   RFALWGD------------------------DFVMGLVKFLLELGCEPVHILCHN-GNKRWKKAVD-LAASPYATVYIG-----------WHLRSLVFKPDFMI----TLGY-------LVNSILER

               IQ-LGV----PLLSS---NDQLMQALRQQM-PSLKVVFMGHGASAFAAYACLDH-MTQRFPARVGAV------AGDAINDMASWKM-ATPWLSGLGNPA

 IINVAVSG-A-------------------------GMISNHLLFKVFPISLKLLGSERSFAALEGVAM-LEDSLRQVSIGI------------DPYEIFQDAEWALLIG-----------------------------------------------------------------------------------DIQIFNALICL-------PK----ENRA------SSAASTAVSIVDAIRSLVTP-FSTGVYT--NGNP----YGI---AEDIV