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SVKTWRKIAIDIIRDFDHNIMPLFGNPKASETISIETKVVDKVAENIIISKFKDLGVNVVSEEIGRIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIVERLYEGIPGKGSYLNGEKIKVRELAEKPSISFYTKGKGTKIIDKVKRTRTLGAIALELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEITFSATEKVNIIAANNEELLETILRSIEK

  MKWDEIGKNIAKEIEKEILPYFGRDK-SYVVGTETEIFDKISEDIALKYLKSLNVNIVSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKSFYEAYKGKGAYLNGRKIKVKDFNNNIVISYYPSKDLEKLRNKVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDLNATDRLNIIVANSKEMLDIILDLL

DERDALRISREIAGEVRKAIASM-PLRERVKDVGMPTKAADRVAEDAALEILRKERVTVVTEESGVL-GEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDDAFFGYVYNLATGDEYYAD-SSGAYRNGERIEVSDAE-YCNAIIYY-PDRK---FPFKRMRIFGSAATELCFFADGSFDCFLDIRKMLRIYDAAAGVFIAEKAGGKVTELDGESLGKKFDMQERLNIVAANEK-LHPKLLELI

 WQECMDYAVTLARQAGEVVCEAIKNE-MNVM---LVTATDQKVEKMLISSIKEKYHSFIGEESVKSILT-NPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQDIKSLLVTELVLSMEKLFCPVHGIRSVGTAAVNMCLVATGGADAYYEM--GIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLM-----SRRVIAANNRILAERIAKEIQ

EMTQLLNSLCTAVKAISTAVRKAG-I-HLYGIAGSQVKKLDVLSNDLVINVLKSSTCVLVSEEDKNAIIRGKYVVCFDPLDGSSNIDCLV-SIGTIFGIYRKNNLVAAGYALYGSATMLVLAMVNGVNCFDRDVKIKKK--GSIYSINEYAK-TEYIQRKYGARYVGSMVADVHRTLVY-GGIFMYPAGKLRLYECNPMAYVMEKAGGLATTGKEAVLD---DIHQRAPIILGSPE-DVTELLEIY

VLMRLVASAYSIAQKAGTIVRCVIAEGDLGIV-QKLQTKADRMVQMSICSSLSRKKLTIIGEED------EDLVVWVDPVDGTKEYTEGLLDVTVLIGIAYEGKAIAGIINQPYYGRTIWGVLGLGAFGF---QLEA-PAGKHIITTTSNK-T-AA--NPDNVLRVGGAGNKIIQLIEGKASAYVFASPGCKKWDTCAPEVILHAVGGKLTDIH-GNPLQYDKHMNSAGVLAALRN--YEYYASRVP

EMTQLLNSLCTAVKAISTAVRKAGI-------------KLDVLSNDLVMNMLKSSTCVLVSEEDKNAIIRGKYVVCFDPLDGSSNID-CLVSIGTIFGIYRK-NLVAAGYALYGSATMLVLAGGSGVNSFDKNVKIKKK---NIYSLNEYAK-TEYIQKKYGARYVGSMVADVHRTLVY-GGIFLYPAGKLRLYECNPMAFIMEKAGGMATTGKEAILD---DIHQRAPVILGSPD-DVQEFLEIY

ELTIVLSSISLACKQIASLVQRA---------------KLDVVSNEVFSSCL-RSTGIIASEEE--P-YSGNYIVVFDPLDGSSNIDA-AVSTGSIFGIYSP-NLLAAGYCMYSSSVIFVLTIGKGVYAFSEKIQIPKA---KIYSFNE-MW-KKYMDDLYSSRYIGSLVGDFHRTLLY-GGIYGYPRGKLRLYECAPMSFIVEQAGGKGSDGHQRILD-QPEIHQRVPLYIGSVE-EVEKLEKYL

ELTIVLSSISMACKQIASLVQRANIN---D-------KKLDVISNEVF-SN--RGRT--GIVP-----YSGNYIVVFDPLDGSSDA---AVSTGSIFGIYSPSNLLAAGYCMYSSSVIFVLTIGKGVFVFLTQLQIPKSG--KIYSFNENLW-KKYIDDLYSARYIGSLVGDFHRTLLY-GGIYGYPRGKLRLYECAPMSFIVEQAGGKGSDGHQRVLD----IHQRVPLYIGSTE-EVEKVEKYL

ALERELLATQAVRKASL-LTKRIQSESHK-TTITKPVTTGDYAAQTIIINAIK-PDDKVVGEES--NY---GRFWCLDPIDGTKGFLRGE-QFAVCLALIVDGVVQLGCIGCPNLGYIFRAVRGLGAFYSWTKIHVRHLKDDMITLESSHDEQTAIKNNISKSLHLDS-QAKYCLLALGLADVYLRLPIQEKIWDHAAGNVIVHEAGGIHTDAMEDVPLDFGGRTL-GVIASSGPRELHDLVVSTSVI

      QELLRVSEKAANIARACRFQLL-----FAVKTLADVLVQEVIKEN--PGLKKIFGEES------DILGIWVDPIDSTYQYIKGLQCVTVLIGVYDIQTPLMGVINQPFGQCYWGLSYLGTNIHS---L---SCRFSVVISTSETIK---GAL-GERIFRAAGAGYKSLCVILGLADIYIFSEDTTFKWDSCAAHAILRAMGGGMVDLECPQLVYHVGQWANKGGLAYRQLETFLS----RLL

KQREIYEIVLEAQKRAVEAAK-----PGM----------TAKELDSIAREIIKEYGYGD--------------YFIHSLGHGP---LKEGMVITIEPGIYIPKLGGVRIEDTVKRLT------------TE

DHLRLWQVNVEVHEAGLKLIKP-----GA----------RCSDIARELNEIFLKHDVLQ--------------YRTFGYGHS----LEPGMVVSMEPMIMLPEAGGYREHDILENIT------------FPII

ASLZIWZKNTAVHRRGLZLIKP-----GA----------RCKDIASELNBMYRZWDLLR--------------YRTFGYGHSV---LEPGMVVSMEPMVMBPEAGGYREHDILENIT------------FP

AQREIYDIVLESLETSLRLYRP-----GT----------SILEVTGEVVRIMVSGLIAHR-------------FFMHGLSHW----LEPGMVLTVEPGLYIAPGIGIRIEDDINLTA-----------SVV

                      LQARGELD-------TTLTQAYLQRIAALDRT----IELNP--------------------------GPL-------------------------------------------------GIPLLL--AYLVRRLRAGAVVLGKTNLSSGSAVAVAANLASVAIGT---ETDGSIVCPAAING---VVGLKPT-----------QDTAGPMARSVADAAAVLTAIGR

AATRARQKQRASLETMDAL--KLQSGELS--------EAVFFTYLGKAWEVNKGTNCVTSYL-------------------QLSQ--------------------------------------------------------GVPVSLF-CVVVQVLKQGAVPFVHTNVSGGEGALIGSGGSPLGLGT---DIG-SIRFPSAFCG---ICGLKPT-----------QLSLGPMARDVESLALCLKALLF

              MIS---ADLQETGELS-------NAAIAQSHAAIEAREKEV-------------------VRHD----AQA--SGPL--------------------------------------------------GIAVGIK-AP-VMMLKAGATIIGKTTTSSGSAAAVGAGMIPLALGT---QTGGSVIRPAAYCG---TAAIKPS---------YSLDTVGLFGARAEDLARGLLAMT

 GEIAKKVREKAIKLAR--------PGM-----------LLLELAESIEKMIMELGGK---------------PAFPVNLSI----LKDY--LKIDVGVHIDGFI-ADTAVTVRMEE--------------NAALGK----KRVNL-MYVRD-AKIKRE-------------------------------------------------------------TLPF

VARSEGASALASVNPLKTTVEEALSRGWSVED-ATKKEV---PLGV--------AAD----------------KLGTIALKPDP-ADGTADITLTFTMGGA---PKNKIITLTRWKCTSDQDIP-----CSR

 AE-HRQVRKYVMSWI----KPG-----M----------TMIEICEKLEDCSRKLIKE----------NGLAGLAFPTGCSL----LQ--DICKIDFGTHISGRI-IDCAFTVT--VK-------------NTGVIVKG----GVVHDDVGH---INEN

                                                                                                                           MEL----------RTLPARKHIALVKQMSVERHQPLLHVLYATGGDQQVGALISEGKIDVLIFF-WD-HDPDVKALLRLATVWNIPVATNAT------------------------FII

                                                                                                                                            GPLHIGLGYLHIIPML-H-LEMYLHEAQTHQLLAQLDSGKLDAVILA--------VKESEA------FIEVPL----------QAMRTIGLVYRLRSRYEQLAEAI

LDPAQRAAAVALSAALT-AAAHAA--TAGA-------QAALDAARAVLDAAP----GV----------------AVDY--LELRD--NGSGRLLVAARLG-----TTRLLDNIA

MKQKVCDVATMAFENAIAKV-KP----GT----------KLSNIGKAVHNTARQNDLKVIKN--------------LT-GHGAP----GMVLAIEPFISSN-DKSFVAQIEHTVTTK

KMKKGK-AVAVALREVRKVIVPG-----K----------TAWDVETLVLEIFKKLRVKPAFKY-------------ATCVSV--------NEVSVDVGAVYQGLY-GDAAVTYIV--------TR---LE-KAI---------------------------------------------------------LGDVSHCI----ESVGFNVIRD----YGT-GTGV----PMVSEGDSRC

 TIMGERLCRITQESLY-LALRMVKPGINL-------REIGAAIQKFVEAEG----F------------------SVV--CG-PQV--MTFTIEPMVNA-G-D-RSLSAQYEHTLT----LR--KDD

  RKIAPGLYKVLSSIADKLQAG---------------RDLDEIITIAGQELNEK-------------------RADDIQIR--EVSETSKRVILVAAW------ARLIDNKMV

                                                                                                                                          QGV-RQVFGIPGAKFDSLLDSSIRIIPVRHEANAAFMAAAV--GVALVTSGPG--SNLITGMATANGDPVAFVSL--------------------------------VD

 YLLFDTIQ--HLEQKAM-----------------------------------------------GETLS-RT-----------------------------------------AMYYANPY----A---YVEQKPTN-----KIFYDSMWHEKMARVLAETLMWACHHSQIMSEISDA--AVIVGSLPYVAG-TLQYIKGLRPQNKIG---STKAEW-----------------PA-------PVKV

                                                                                                                                          IGLKHHFAVAGDLVLDNLLLNNMEQVYCCNELNCGFSAEGY--AAAVVTYSVG--LSAFDAIGGAYAENLPVYLE--------------------------------AS

                                                                                                                                             PLIGLLFSQ-GALLAVE-IETLSQDPRYRLCAEDFIRNRVRFLVG----YMSHTRKAVMPVVERADALNIVYG---------YIY

                                                                                                                                            PGQYVAGMYFTTRFHQEKNGATFVDIVRDLNKLALI--A-IAYICLAVTPVSMANMRAVHEMASTYGIKIFYD----FSY-----------AD-DEEM

                                                                                                                                            NVKVGIID---HVGTVAAAVSLYAIKVAIVSGIEWATQNGLDVINMSLGG-SGSALKQAVDKAYASGIVSVIALE-------------------ASQVR

                                                                                                                                             MLRVAVSEPI-LAGYRVNNVEFFFL-RPKDIAIYVGSGELDFGIT------RDLVCDS-GAQV---RERLAL-------SFRVVG-EAVLIER--DLVARVQGV

                                                                                                                                            GVDHLYGIPGG-MDALSAERIHYIQVRHEEVGAMAAAAD--GVCFGSAGPG--THLMNGLYDARHVPV-------ADV--------------AYA---VV--QI-PV

                                                                                                                                          QGIDTVFGNPGSNELPFLKDFPFRYILALQEACVVGIADGY--AFINLHSAAG--GNAMGALSNAWNSHS----AA--PRPL---------------AI--------VPY

                                                                                                                                             KVICQG----HSEQAITKMVGGV--PFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIG---------------NC------------VITIGIQ

                                                                                                                                            GSLYVATARYALPGVIFI--SLHMHQGSPTQIAEAVSKGNADFAIAT-------EA--LHLYDD---LVMLPC----------SE-STTKIGFRR-SY--DFIQRF

                              IPQ-----MVKHRLL------------------------------------IGP---------------------------------------------------------GRIGIVSGTLEAVHQTTLGQSLCV-TDFTDCLEIFLNDPTEGIILIGEIAEENAAEFLKQHNSGKSKPVVVVS---------------------------GTT

    IRSCIVFFESK--------------------------------------L-VASF-QMR-DRL------YSKAVHVD----TFNMAGVSADYFRINSPPLPRAVAAKIRGSDVEFGLRALASGYVKEVV

                                                                                                                              TPY--------GA--DHLFGVPGDLQLDHVIDSDICWVGCANELNASYAADGY--AALLTTFGVG--LSAMNGIAGSYHVPVPGYLM------------------------------VA

 YLS---KAPVLYRALL--AREVAGQGGSV-------AEALRAGEEALRAVPE-------------------F-RKDYLAIVLS--DWVAGARGIVAGR-FPE--ARLIDNLE

                                                                                                                  NTAG----------------------PGDGVIIIVYYPFMAIKNQERKIIECEKLEKLSKD---KNNKALLFCSPH-ELQKIKDIVLKSD----KTITFIIK

                                                                                                                                            NVKVAVLD---HVGTVAAAVSLYAVKVGIVSGIEWATTNGMDVINMSLGG-SGSAMKQAVDNAYARGVVSVIALE-------------------ASQVR

                    IIP----AHQ-------RGAENILFPVLLKYKQKEG---------------------------------------------------------------------------------KAKN-PVFISFHFDTTAHVELNGCKAINIVTFDIKLKEN-IAQIVAIVSTVTPVSMSNLKEVYEIAKQHGIFVALTVAIR--------------GGLAGRDMAAMVQGLE

                                                                                                                                            EDIKVAVEFTG-EQAVANKLQ-IAKYDDAVAVANKVVNDGIKYVIG----LCSSSTQPASDIYEDEGILMLRT---------ITAEGV----------LVT

ARHLVRMIAAGTAAHSEHGRHIALAMQ-----TLG--IV-DL----------------LAA--VKRL---------PHNI--------------DAS----------QT----------SRT-GC---------------GAVNIAVNNPM-DIICDVAINIIGITNY--SQELPILTGALEAMVVD-VQC---IMPSLPRIAECFHTQIITT-------------NK-----------TII

                                                                                                                                            GQEIAVID---HVGIAAAATRILAVRADIADAIIYAADSGAEVINLSLGCDCHTTLENAVNYAWNKGSVVVIAVD-------------------NIEIR

TMREITETIAEAKKKVLDVTKEAQAN------KHGMTESFEDNVVRFLNEARDKAGNNV-------KQ-SFIAQ----ACVGQQ-----KDDYSPFVENSYL----------------------RGLT------------------------------------PQEF

                                                                                                                                           LYLNKAVVGSGAFTA-LAMVLSNITFTSDVEKAYNGA-----EIILFVIP-FFEKSGGNLIAYAKEKQVPVLVCPAEIGEF-------------------SV-LA

                                                                                                                                          VN-NTVFGLPGDF-LSLLDKIGMRWAGNANELNAAYAADGY--SCIITTFGVG--LSALNGIAGSYHVGVLHVVG-RMSAN----------------CI-----LGL

                                                                                                                                            NVKVAVID-----GTVAVAASLYAVKVWIINGIEWAIANNMDVINMSLGG-SGSALKAAVDKAVASGVVVIAVLD-------------------NTQVR

                                                                                                                                            DDIKVAVEFNG-EQAIKN-KLVGVEYDDAVAVANKIVNDGIKYVIG----LCSSSTQPASDIYEDEGILMMRTA--------ITAEGV---AE-----LVT

SQ---DVMRQQVQKLAFELQV--------------------------------------------------------------AR--AG-----------------------------------------------KK---HGRALLSDKEVDAKLLKQGFELDATHNKVHIQDRIKNGEYTYIINT----AIEDSRVIRRSALQYKVHYDTTNG--------------------------GFA

ARNVGLMILTGAAAHCEHGNHIAHALVVGE-------KALE--------------------GE-RTH---------PFGI-------------HASI----------LV-----------AHMG----FSIL--------DQVNFVLHNPLIIVQAAR-INLVGICSF--SQELAICTGAIDAMCVDVQ-----IMPSISAVAECYHTRIITT------------NAK-YH-AIEA

   LEGEKL---YRDMLAARMLDE---AP---------AAGHEAA------------------------------------------------------------------------------------------------FDWVFPYYRDHGLA-LG--LNFFT-AHVPPAAGAAISM--VAVCTFGDGATSGDWYAGINFAAVQGGPSLVEL

                                                                                                                                            GVGKVFGVVAASIL-FDEVGIDFVLTRHEFTAGVAADVL--QACWATLGPGT--NLSTGIATSVRSPVSFISL--------------------------------LG

                                                                                                                                           ADTRIGVTI-FMVRKAIEQDAQLLMNDSKQNDQIDVLLAKGVKALAIN--VDPA-AAGTVIEKARGQNVPVYYV

                                                                                                                                            GVKVAVLD---HGH-VGTIALYAVKVLSIAQGLEWAGNNGMHVANLSLGSSPSATLEQAVNSATSRGVLNAMALD

   SSVDQP----------------------RDKVGKVEANNAFDQYRDLYFE---------------------GGVSSV-----YLWD---VILIKKAGDGS-KGCWDSIHVVTSTVMLWLQNLGGSLT-RQTVSDS--------------------------------VEDMENK----------------IRS-----LNEIY

                                                                                                                                              MNILLFGGWEQRSLAPVGNLIALFCGVAETVRKL---RPDVIVNAAAHLNATSVEAIAKAANETGAWVVHY----EKA

                                                                                                                                            SGAKIAI------GIAATAASILAVRVAVANGITYAADQGAKVISLSLGG-VGNGLQQAVNYAWNKGSV----------------PNYPA------------VASAPG

                                                                                                                                             KDTIALVFVSGAKEADKLYNLVVLDSKELANVQDLTVRGTKILLIN---TRSDAVGNAVKMANQANIPV----------------RQ----------VVSHAS

                     NTS-----YFF-RASFE--GNP--------------------------------------------IS------------------------LMA---GM-------------------AGGHIVTTCYRKTIFIEILPITATVIDADVGALELALNQKVNLFFTETLRCVD--IELVSKLCHEKGALVCID---GA--GGHNDVLAGCISGLNPNAAYLIIRGMLH

LAEAKKDAILKDLEELIAIDS--EDLE---NATE-PVGKGPVDAMTKFLSFAKRDGFDTENFAG-RVNFG-----IGHMDVV----PAG----DDKLTAMFKP-----------------------------------------------VGIKHE-PTPD-------SPDAE---Y-----NGE-TISGPDLEAVKLAYESFLAELDGSFE-------------DESADIVLIGGKNS----SMFDY

PFEQRHIVDGFSFELSKVVR--------------------PYIRERVVDQLAHIDL----ELTDDLNIT-----------------------------------------------------------------------KGRVVAI-DLLALKALKAKGVHAKLLYS-FAAPS----LTVDAVIVPCGNIAADNANYYLMEAYKHLKPIALAG---KAT-------------------ELL

                                                       GIDVCSFSA----------------------------------------------------------VTNGGK-------------GDEVIIPFWVSPEMVKLEGTPVILPTVSPEQIRQ---ITTKLLVFNTPSYTPDEVRAIAQVAVEAGLWVLSDE--------DA-QHLSI---VCTFAQYGAIAAYE

    PSDFDAKAKEFIAKL----QAAKIAS-------RKASQNAIEAFGPLL----------------------------------------------------------------------------------------PEFLGGSLAPSLT--LWSGSNYIHYGVREFGMTAIANGIGFPYTSTF-L-MFVEYARNAVRMAALMKPTALIL

                                                                                                                                            SAHVCLINATA-LKNLVLIGSFTIIDGSPEL--SFF--CRFTVVVAT--QLPESTSLRLADVLWNSQIPLLI-YMII

                                                                                                             LPAKQ-------------------------KKIINVAVAAGMNLFKLASGLRQVSIGIDPYEIFQDA-----EWALLIGAK-IFAEQGKALNAA--PNVKVMVVCN--ALI

                                                                                                                                            MALKVGVVFGI-LD-WR-WNSEYVRQNSISAGITAVAEGELDILIGP-ISVTP----ERAAI---EGITFTQPY---PNLIRV-SLEPYGFVLKQKTINVE

                                                                                                                                              LKLAIEEKTYLKKTV--DIVCFV--RPFDVPTYLVHGVADIGFC----G-TDVLLEKET-----SLIQFFI--TGR---IF--VIRTHVVVNY-VVLEKLQEVI

     PISVIGGL--------------GPES-------SGKTTVALHAVANAQAAGG-------------------------------------------------------------------------------------IAAFIDAEHALDP--KVDSLLVS--IADMLVRS---GALDIIVIDSVALMSQALRKMTGALNNSGTTAIFI-------GG---KAL

                                                                                                                                          DPT-AVIFGEGVFRC--TVGLRRVFNTPLCEQGIVGFGIGIATAIAEIQFADYIFPAFDQIVNEAAKNCGPCIFF--------------------------------EPK

                                                                                                                                           SQIAICIWVESTALQDCQRAYQLQVC-EMLLEYAQTH-RDQIDCLILVANPSFRAVVQQLCFGVV---VP---PA-EQL------------------------LQL

                    GVYF-----------------------------------PVATGI-------------------VNDANVG---ARSTG--------------------------------------DAG-GKRVVVGEQNRQ-LTFDDLGQAIRVSA-SQGIQL-QDKRADALFY-TVG-GASAIQQLALTTP----IALVA-----TY------------------------TVAV

                                                                                                                                           KTPMRVAVAAGQYLFRIANGLAGMTAHADPMTAFKDA-----DVALLVGAR-IFTVQGKAIDAA--RNIKVLVV----AYI

                                                                                                                                            GLRQLRIA-PHFMSG----FGEDRILIVTDALLKEIEADKYDAIILNDM--VDECLGKVVDAILAKGGIAIIT-VIVT-----------------LL--GL

      SLRSDLINALYDENQYD----VCGII-----TIFELFSRPIINKIAEKHGYIVEEPDFTL-YK-PSEKIAID-IKT-------TY------------QYIAHWIIGYV---QDK------WVI-----------------------------------------------AGDLA-TN----IG--------EG

   EKQRYLEEADRKLRQIEQAYEMG-LTD-------RERYDQVIQLWTETTEKVTPF----------PQQIRQ-----MRGLM----------VPVRS-----FRE----------------------------------------------------------------------------------GLTVLEYFISSHGARKGG

                                                                                                                                         LVN-RVLVQG----HTKQMLTKIVAGVTV-AAADAALEAAHA--ILIVLITEGIPTLDMVRAVEEIKALGSRLIG---------------NC------------IISIGIM

     AATVYADSTAAHADMQGRRLKA--------QD----------WEQGG--------------AKTGENTTAAATLGMG--------DSISLFAGIRHD-YLKGLFSYGRYGTLMQLGAL--LRYDL-GTLV--------GADVEFG--------------------------------------------------------------------------NGLARYS

         QM-EI--EYF----VRPGED--------EYWHRYWVEERLKWWQEMGLNLVPYQ------------LEGIAQR-----TDFD--EPSAGVLLA---PNGE-----------------ERI----VLKLKPQL-KVAVIP-EIYARLKARLLVLYEDTGNIGKAYRRHDEVGTPFAVTVDY----------------DTMEQIRL-----------------------------HVD

                                                                                                                                             DSRVLI-GCA-QYLASAGVGNLTLLDLDDAELAALIAE-HDLVLDC--TDNVAVRNQLNAGCFAAKVPLVSGITVF-LSR-----------------AIK

    TMGERRRFWEKFFVNLAQSLANA-DE-------KAVNATTERLFSEP-----------------------------------DH-----------------------------------------------RG-----DIVVYDVSDIMNLVRRDADRVFVG-PQEEINQILLREGK-VVRLKGGDPF--RGGEELETLCHAGIPFSVV------------VE--IIVGRVAL

    FW--VSKW--V---------------------------DYSGLGLF--RLIYI---------RDGTE---LRTWFRTR---------SAIILHLSN-----GSVQINFFQDHTKLILCPLMAAVTYRTY--------------------------------------------LAS-----AR-------KLL

                                                                                                                       EE----MAK------------PRVVVLGEGVFLVTE-GL--RVMDTPLSEAAIVGAALGMLRPVAEIQFA-DYIFPGFDQLVQVAKLDPVVFLE

   AEHAAIQAA--QDKRMDEKMAKR----------------------------------------------------------------------------------------------------------------REVRQVGVVGTGHIGQVFMRIMEVIAYVDSLDDLYKQA----DVISLHVPDVNVH-MINKSIAEM--DGVVIVNC---LVD--------------FGF

PLANVKAHLTQLSTIAANNGG-------------------GRPGYKASVDYVKAKLDTTTLQGYNLIANW-----AHLDSVS---------SGAGNGSAV-HL----------------------NNLIG-YFVYD------------DDPVEKTFKNYFVPTEIETE-------------------------------HAPFKNVGV-------------------------LDSDAAAHAIWTL

                                                                                                                                           NV-DTVFGYPGG-YDAIHS-KFNFVLPKHEQGAGHMAEGY--GVVLVTSGPG--TNVVTPMADAFGIPMVLVDL------------------ARRAAGRG

IRRYTFEIIRN---------TA-HSTKEE--------ENQVKEAISIYKKFFDTLGIPYLISKFDT---------QIATVHNL----GQNF-TCYGISDRIA------------------------------EKGLILPPI-QVVIVPMEKEIEKLKGKFRVHIDDRRPGRKFNDWEIKGVPLRIEVGP-----------------TMEKFQVD-----------------------------QL

                                                                                                                                        RG--HSPLVHS--VVFTNGLLALGASPVMAYA-KEVADMAK--IAGALVLN-GTLSVEAMIIAGKSANEHGVPVILD----IREGV------------LFAAIAAISSYG

RRT------TWLHQALRE----------------------------------------------------------------------------------------------------------------SGA-----ARIRETLGIIGGRVGQAVALRAFNVLFVSTLQDLLFH-----SDCVTLHCGLNHH-LNDFTVK----QGAFLVNT----EKA---SEP

                    VV---VTDTT-------SINLFKVLSAALRVQATR----------------------------------------------------------------------------------SPE-RRVIVTENFPTLYIAEGLAYTLRLVDELPQAI----DQDTAVVMLT-VNMHD---A-LTALSHECGALAIWD-LH--------------------AGADYAIG

                                                                                                                                           DN-VVVYGQGVFRCTE---LQRVFDAPISESGIVGTAVGG--PVVEIQFADYFY-PASDQIVSEARLAPVIFLE

                                                                                                                                         NGTNDTPVYVSTWENHGVFTTGFKDIRSYRGFLSDLENA---P-FSIFVLHADPTPEQWKQIASVMKRRFLFP-------IRY------------------LF----AQSF

                                                                                                                                           KAPVRVAVAAGQYLFRIAAGLAGLEATDDPDVAFKDA-----DYALLVGAA-IFTEQGRALAEA--KDVKVLVVAN--ALI

     PISVIGGL----------------PE------SSGKTTVALHAVANAQAAGG-------------------------------------------------------------------------------------VAAFIDAEHALDP---VDSLLVS-EIADMLIRS---GALDIVVIDSVAAMSQALRKMTGALNNSGTTAIFI------------KAL-----------------MDV

 SESITRTVNDILDNVKAR---------------------------------------------------------------FD--KTTV--------------SER------------LK---------------------ASVGLYTVL-ATPASIACKKVVLCSAIAALAFG----KVDKIFGP---GNAFVTEAKRQVSQRL-AAIDP-----AG

                                                                                                                                            TRLRIAMSDDELLAGI--MPIDILRVRD-DDIPGLVMDGVVDLGII------ENVLEEELL---DPRYFTRRL--------IY--RSKACLIQRKQ-I-DKLL

   TGELLEKSVNTIRFLAIDAVEKANS---------------------------------------------GHPGLP-MGHVLYD-EVM----GC----------HP------GVEVTTGP---GQG--KH----TG-PGLIGGSLASS----LLK--RNVRFGVREHGMGAICNGI--PYCATF---VFTDYMRGAMRISALSEAPSILA

                                                                                                                                         RV-RRPLVHNNFVVTTNALLALGASPVMAHA--EL-EEMIR-LADAVVIN-GTLDRRSMVKATEIANELGKPIVLD-VL----GE----------FN--EPLKATTSALFG

 ARAQVSEAILLAEGQKSAVTEYYLNHKW---------SA--GVAS-PSDIK-------------------KEV----EVKN----------GVVTATM-S----IKKLSLWARKWFCGQEILPS----CR--------------------------------------------DAK

         AI---------RASKKD------------------------------LEGGH------------------QSSATIYDVCHFF-HI-----------SYP-----FPTVS----DP----LPSRQPNFTEKDRLVPIIA-TFGMG--L---QILQEGINELGAGCSWLAANLIPFYIYYSMF-FQRIGDLCWAAGDQQARYYYI

NAP--FSN-TRSVAELVIGELLLLLRGVPEANA-----------------------------------------------------------------------------------------------------AG-SFERGKKLGIIGGHIGTQLGILAMYVYFVQHLSDLLNM-----SDVVSLHVPSTKN--GAKEISLM--PGSLLINA----IPA--FPTE

ARGLDRSIAAGAAGHSGHAKHLAHTLK------TEGQAAL----WV-----------HGLI---------------PAGI--------------DHE----------EI----------MHRGC-------LF------DAVNVAVHGHNPVSDIIVSSINVVGICHS-VSQEMAMITGALDAMILD-YQC---IQPSVATIAECTGTTVITTM--KITG-----------AT------QIL

                                                                                                                                              EVAAIYSSTMEE--AKNTLTIREMQGAAGAVHGALAAGALTTTFTASQGLL-LMIPNMYKISGELLP--------IYA------------------AHLHF--FDG

                                                                                                                                              KKILIVDPIIIFNMTKEGYEVVTAFEALEQFEA----QPDIIILDLM-DGLEVAKTIRKTSS---VPILML---GLEL----------------ARV

                                  LGAL----------VKGIGSD-----YG---TTPLSENWSVAPA--MLAQR-SK-YQWATFNLRLIQA-ALAYEGSYQYMGSFYKLTFAFYTSWMD---------KK-------------------------------------NYASD----------------------VQMETWF

                                                                                                      QAGQ----------------AP---------------GQLVAVVTA-----L-LGHLKGICFSAEFVFAAGLSLLTNERFMYLSTTDY-FYAMMDSYFKRYHEQGAIVAIT------------AD-DLVVLGE

QQVQVIEMLQKVTLDIKS----LSA------------SQVISQLKQKLENLQNSQ--ALAIE---------------CKVMA---------S-PLWLE---ADIG--IIFK----GD------------LRQDML-LR-LDLCLL-AT--------------IAK

   FTDIDKLAVSTIRILAVDTVSKANSG---------HPGAPLGMAPAAHV--------------------------------LW--SQM------GH-------HP---------GVEVTT-----------GMASGQPELIGGSLTPS-L--TRWALRYIRYGIREHAMGAIMNGI--KPYGGTFLNFV-SYAAGAVRLSALSGHPSIIA--------------------------------LSR

NMP--WNSIS------------MQAGATA--------MAYTLADGVDYIRAGESVGLNVD-------------QFRLS--FFWGI---------------EVKNPKSMSRTHSQLH-----SGSA--------------RR-RILLAKDRGVITAYADFDVDVGPLFQTPEETARQA-VEADVVGVSSLAGHLTLVPALRKELDRPDILITVG----RKD---------GA--------------YTP

                                                                                                                                            NVKVAVIDS--HGGTIAVAASLYAVKVWIINGIEWAISNNMDVINMSLGG-TGSALKTVVDKAVSSGIVSTIA----------------------------VGA-APG

                          LKGF---------------------GKGLS----HG-----SMGD--NWDMM--YVGMYQDI-WWTVGIRPMYKWTPIMSTVMEIGYDQYKITLAQQ--VFATY------------------------------GNAFGK--------FGRG---------------------------AQMEIWW

EMNKVMELEKEIANAT---AKDRNDPMLLYNKMTEDVVVYAPEYLTKL-PILTKYSA---------------R-----------------------MS--------WR------------M----SR----AFR--TATWRANYNGN---------NAV--------------------------DNGR----EQSQCMVYQYGNFHLNGI

              EM----------------KEKYD-------IATV--KLE-------GTS--------KCKVKLTISDDL---------GQTTLEVFKEDTLVSKKVTSKD-KSSTEEKFNSEKIIT-EYGT--WN---GTS-------------------ITKL-IKNALK

                                                                                                                                            QKIEVLV-VRPAIEYALR-RFQVAYEDSALFSLV---GAKPDLILG----VCEYAAAPVARLASHWDLPMTRV------AKMG

                                                                                                      HSSG----------------------------GSQ-----KKIAFG-ILEIAHLVERGVEVIDKGYASQVALAVAGGEVDGGILICGTGVG-AANKF--AGI----RAVVCSA--------RVVG--------------VDA

IWEEIQEIIVSI--DAEAC--RTIL--------------SPVALNEAFKEKLEAKGWKE-----QTD---KDRVAIEVQFGK-------------------IDVG--EILPMEL----------------------------------------------------GISYY---------------------EGELYNV----GVPAVPLVLI

NKDLISAGLKEFSVLLNQ---QVFDALVSE-------EDMVTVVEDWMNFYINYYR--------------RDLQRQLNALAKYRDFLKS

                                                                                                                                          MEKKT-IVLGVIGSDDHSFTNFNVVNIGVSQEDF--A----KADLICVSSLYGQGEIDCKGLREKCDE-IKDRVY----------------------EVL

                                                                                                                                             CVYVIDT---HCGTV-STQLFGVKVLTIIAGMDFVASDK-VVASLSLGGGYSSSVNSAAARLQSSGVMVAVA------------NYSPA--SMA------PHV

                                                                                                          EFHVLQQWPTK-----------D--QEAV-IPAENLPLQARH-------------------DSRLLAEIIHAGGWTSNEGSYNV-SLLDWQYCDRLVGFYEINRE-GI-ALLA----------VT-----------TVFHQ

                                                                                                                                         IV---KHVTVIGGGLGQVAAATGHTIATSTDAASVVHST-----DLVVEAIV-VKNELFKRLDKFA-AEHTIFASNT---ANA--------------SLDF-SK

TPF----VA---ANKIDRI---WR-------------IQVQQKLDTKVYELVGKLHFESEFDRVTD--------------------------------FAS-------IS----GEIPTLGLQYL-----------------AGVVVKASLEAKILRDYVPIKVADI-SRRDVVNAG-IALGAIIAF-NVKVIPSAAQELK---NSDIKLFQG--------------------------EY-EE

                                                                                                                                             MKNVGFILMQRMRD-FDAI-RPVFFSTAFD-LEALK--ALDIIVT---CQGGDYTNEIYPKLRESGWRTFVGG

                         KYGDRIAITTHWSYR--------------------------------------------------------EL---------DTR--------DR------------------IQKDRVVVQLPNIKEFEVIFALLPVFALSHRSSEITYFCEFAAAAYIIPAYSFD---L---RQVQSKLPLK---EAEEF---------------------LP--LE

                                                                                                                                          MSLAIKVLI-LL-ALQQLG--FKQITAAGDGEQGMKIMAQNPHHLVIS---DFNMPKMLGLLQAVRANPTKNNVL---------AKP-----------------AIE

                                                                                                                                         NN---VVIVATAGA--ALIKDLITGIQAL-SLARQVNDLVKK--GVVITHGTDTMEETAFFLNLVV-HTDKPMVLMNDSIFAARDTKG----------ND-AKEIQNMF

                                                                                                                                          PR--RAMIVTG---FAEYGRALA--RWSLLTDAILEALTPD-LDCLFLCTPLPERPLLQAIADRCKSLNINIWVL--------YAIPLR--YLVNSDDAAMAR----QM

TPMSIIAGRLS---------------------------------VQFGARFLER---------------------------------------------------------------------QGGR----------GVLLGGKVVILGGVVGTEAAKMAVVQIFLYEIETAVAEA-----DLLIGAVAPI---VPASLVEQM--TGSVIVDAV---VETL

 SEDMQQDAVDCATQAMEKYN------------------IEKDIAAYIKKEFDKKYNPT---------------WHCIVGRN---------------------ETKHFIYFYLG

ASHRGRLLNR-----ERDR-----------------------------------------LET-PYV------YLVD-LD------------MVL-------------KC-LRYY-----------AGW-------------GVCGQ-QAW-LGPALATGNVVVMKVAGAAIASH---EDVDKVAF---TGSTEIGRVIQVAAGSSLKRVTL----CGGGI---GYF----FGDIAKE

                                                                                                                                           GITVNPVQETF---LLVSRYTVNKPSEVDYNVGYTSLASGDATFTAVNWT---PLHDNMYEAAGGDKKFYREGV--------AI-YTW-----------WLQ--YGF

                                                                                      LVSD----------------------DP--------------------------NNVAVIS-------------GMLAAVCG--AVLTAIQAVT-GCLLIVKNYTGRLNFGLAAEKARRLGYNVE-----------HPRG----------NLATVLREAQAA

         QME---IEY------PGE----------EY--RYWVEERLKWWQEMGLSRE-------------NLVPY------------AKATVDILYRFP-------GIAQRRGRE-EE------RI----VLKLKPQ--KVAVIP-EIYARLKARLLVLYEDTGNIGKAYRRHDEVGTPFAVTVDY----------------DTMEQIRL-----------------------FL

                                                                                                                                            SDLTVAV-RVPAVELALA-TVRMVLGSSAPLAAVLK--WSPAVFLG----GCVYSAAPVGRFTAHWRVPLTTRT-------LGDRP

                 LV---DASKA---SQ-EDELFDMSIQCIQSVYISKIISSDRDLLAV------FKNIYVLQ----------------KREL-----------DQ----------GQK-------------------------------------------YSLSEVLWVCANL--IMLFTNEDNPHASRARTKAGDLRDTGIFLDLMH------------LFY----------------SS

VSLL--GI---KVLNNPAKF---------------------TD--PYE-----------------------DLEWKLT-YVGIPSE--LVSVTVILLSCSYDGREFVRVGYYVN-LKPRVTRFN

   TLKELYAETRSHMQKSLEVLEHNLRYA-------EEGRVAIRNIRREALDKLK---------------ETKEAQTDIAKADQLAEK

     ELADPQLYKTFTD-AAEVIGEAKA--------VREIMALADLANRYVDEQAPW------------VVA-C--F-LMTYLK---TWD--------------------GI--QQPLLG

                 YFIAVAEELTAGH-------AFLEDARRILELAGRSGDRDV----------------------------------------------------------------------------------GELSVAYFGTRSLPLLLR-TVSLTH--TKDEQVEGLLAGTIHVGFSR---F----FP--RHPGI----EIVNI----------DE-VPISCIFRLARFVEHV

    LG--TPTATP--HYCF-CY------LLD-----RF-----------------------FA-AQDLD--------------FTDLMAPG--WTAEV--------------------------------------------PVALVLVYLFSALRRLGLDVDVVP-PGASLR-----GYAFAVVPSLPIVREEALEAFREA---EGPVLFGLYRE----------------RY---LY--AAW

SQF--PIALVQ-TT--RDEP----------------------TEI---S-------GW--------QQLGDKTRVTLLGD--YAH----FLSKTLYGALEHN-SGFVRGYGYDNLYSQSWDAGLITSYSH-KQ----------------------------------------SY--APNKS-YN-------------KAR------EATA--HT-----------------------KYYQ-DY

                                                                                                                                             SVKILVVEN-VIRMLNLGIENIELACEAFDKVKELT-GENYNMIFMDVQDGLLSTKMIRRLGY---TSPIV-FAIKLES----------------------KLK

     VETIAGGL----------------ES--------GKTTLTLQVIAAAQREGK-------------------------------------------------------------------------------------TCAFIDAEHALDA---VDNLLCSDTICDALARS---GAVDVIVVDSVL-MSQAMRKLAGNLKQSNTLLIFI-----FY

                                                                                                                                           DKELKFLVV-TMIVNLLKEGFNNVEEAEDALNKLQ---AGGYGFVIS-DWNDGLELLKTIRADMS--ALPVLMAQAG-----------------ASG---------YVV

                          KGYN------AT------------GKGQAR-DH--G---A--LGD--KWDLM--YVGMY-NIDWWTVGVRPMYKWTPIMSTLLEVGYDQYKITLAQQ--IFATY------------------------------GDNISR--------NSRG---------------------------AQMEIWW

                                                              QYTS----------------------------------------VSDL------DG--VDYPK--------------YRKHKILVINHPITLLPLYHLHEFEVPKKLADVV-SLNDSEYAAIFVPALIGLSQDVAAALQWAIKNDRFVISLC---FLLRH--WYF

                                                                                                                                           AFDLYFVLDKNWIIYNFVQA-LSFIVFSYIHEGLKLANEQI-IIIALTDGKLDPSYAEKEAKISRSLGASVYCV----ERI------------ADSKEQFPV-AL

                                                                                                                                            PGQYVAGNM--------KNGAVFVDIVRDLKKLQK--IDEIAYICLAVTPVSMANMRAVRELTAAHGIKVDGCCMN

                                                                                                                                       PRSLAAPIMILNG-YG----VEALCVDFRQSNELVDWIHEARLNH-GIVINPAAYSTSVAILDALNTCD--GLPVVEV-----------FRHSYV------ERIAA

 GYAIWENIQQ---MF-GHLL--TAHATEA-------EEEVRRMLSIYARLAREYAIPVIEGLTTIEA-------QAGTS--HYL-GE----SWGLS-GAIM------------------------------DRGLVLPPR-QVVIVP-EAGLQALLALRVHLDDRDTPGYKFHEWELKGVPFRVELGPK----------------LGGKETL-----------------------PL-----AL

   EKQRYLEEADRKLRQIEQAYEMG-LTD-------RERYDQVIQLWTETTEKVT---------QSGPQQIRQ-----MRGLM---FE-----VPVRSSF-------RE-------LTVL-------------------------------------------FIS

                                                                       PDNINADISLG-------AAIIKGAINWDLMPQISIGAAGWTTANEFDLNIK--AGYQE-KMPY----------------------------------------------------------------------IGL-GSY-------------DFELGGTF

                                                                                                                                              SKILVIVSLEIGAANGLKDKVVVAVSVSAL-IA----NPSVVLLP-SVDSLGYASSLASKTG---YGFATDV----------------------ELVA

                                                                                                                                          PQ--VTILATGGT--KLLNDTIKGEQISVWLAKRVNELLAQ--AVIITHGTDTMEETAFFLNLTV-KSQKPVIVMNDEIHAAR----TK----FV--------TESLN

                                                                                                                 PHLPEKYKS------------------DNDLVFGQYR--AG-VLYR-RHFVTISQIPQAVGAAYAA--VVICYFGEGASEGDAHAGFNFAATLQPFLIEA

 VEALRTLHLAHNCAIP---FEN--LDV-----------YCFELNGLFERALRDIGFNVRSLL---------DVWIADVGFG----------GQTLPL-------------------------IAQQTPH------------------------------------------QFRH---HEHWQ-----CFDL

           PQE-LD-TIYLM----PKEAD----AIGLLEVGTAALASID-KNFK-----------WKEN-EKSITLVANVYRRKEGNKPRI-----------------------PEP-------------SD----------EPTTD-----------------------------------INAMD

                                                                                                                                                       FAFELRKATGKIVMG--ARKSIQYAKMGGAKLIIVA-RNARPDIKEDIEYYARLSGIPVYEF---------TS-VEL---------LAL

                                                                                                                                              MIALDG------------------QILRSALSLSMIT-QPFTITSIPGLLRQHLTAVKAATEICGATVEG------AE-----LGSQRLLFR

                               WGQ--VN---------------------------IDAKPLDVRFTTKIE-----VVDSV---NTLNVEVDIAIAVGEGSLSVGDFSHSFSFE--KVPLD---TWFQQS-----FWF----------------IGPA--------------------AA----------------TRWKFSHAG--DSLFPV---------------------IEVK

  IALALTIFVWVFLMNL-MDLEH-VVPSA-------DVNVTLSMALGVFILILFYS-----------------LSGL-FGNYAGELIF-----WA-II-----------TLAF----MVLVY

                                                                                                                                      GSH-----ADVVLYALVSQDLIAKSKPAEVL-MEMVGTMLDRMREGKMVVRVH-GAI-MEQMVLLKREGV----DIEIVPVRTTDLD-RKQ---MILAGWALD

  SHVTGWDNMFEGIARYFTLKSM-----------------------------------------------------------------------------------------------------------DDKVVGS---NKKINIV-----M-LSEMGVGYSLLS-------DAPN--ALNTVLLQPWHLEKTKKFVEGTWK---HEVPKL------------------------EI

                                                                                                                                              KRVLIV-M-MLDIITKGYEVAGEATEAVEKYKE----LKPDIVTMDITNGIDAIKEIMKIDP--NAKAKDF----------------------------VEA

   TYCNSISVA---VMMILS--------------------------------------------------------------------------------------------------------------------DL-EAMHVGTVAGRIGLAVLRRLHLHYTHATREDMYP-----VCDVVTLNCPLTEH-MINETLKLF--RGAYIVNT----CD----PQP

                                                                                                                                          AN--VVLATGG----K-LIA-RGEQVM--DLLKLGKRVAEL--IVITHGTDTLEE-TAYFLDLTL-NTDKPVLVTEIQSGRD-----SK

       CLHSCN---GETD-TTTGV-----NLYK------------------------------------------------DSKSKF---NL----------------------------------------------AGKVAVVAGGDVGKGCAQALRRVIITT--DEACQE-----GNIFVTTTGCID---LGRHFEQ---DDAIVCNI----VKW-----------RYR--------VN

                                                                                                                                  NH----TKS---IGLLAT--YFAEIIEAVETLLGNAWKQRAYLSMMAQKRVGLLVMCS-EYPEPLLAMLEEYRH--IPMTDAVI----------ERN

                                     DVR-----------------------------NL--NQYQTRGAF--------YARFFWQQTG---QDRYRLLLTNPTELELNAQPGNVQLV-RYT-EM---------------------------------------IGKLTG-----------WI----------------------DA------RLSEI---------QNGKN

                                                                                                                                            DEKVFLLGGAYK--VS-GL-YRIIDTPGFAGIAVGAAAGLRPICEFT----FSQAIDQVINSAAKPVPPVVVLE

                    DRHALKT---KKAIISITY---------------------------------------------------------------------------------------------------VR-GDTVAVYMVPEAIITLLAIIHSVVFFSSNSLRDRIN-DGDSVVITTDETKR--IVDDALRET--PGVRHRDLD

    VNPFIKEAKEKMKRTLEKIEDEL-IV-------EEGKIAIRNIRREILKKIK-IP------------EAKENQKLIEKLDEVFEI

      SPADTLYLLNMGKVQ---------------------------------------------------------------------------------------------------------------------KEGQQTVGVMGTGHQVAIKLFKAKVIAVSL-EDLFKQ-----SDVIDLHVP-NTH-IINEAAFN---PGAIVINT----IDT

    ISDIRKDAEVRMDKCVEAFKTQIKIVRG-----EQARVAVRNVRRDANDKVK--------------EDDDQDQKAIKKIEAALA

   SDEEKVRIAAKQY--MDQ-------TPVKIYDDQVQWRDACDSALRAYVKDHYPNGF----------------CTVYGK-------GQQTIIACIESHQ-GRWRSEWKFTI-QVAAVLK-HKDIQDS---VQ-------------------------------------EYQT--AISE

                                                                                                                                          LDPGDEIVFSP---WVSYIPQIGTNVVETPSLEEVEGL-LVKTKAVLINSPVYRREFLEGLVRLAKKRNFYIISDE----------EFTS-----INTVAQYAALKALE

   DREELGRNTWAFLHTLAAYYPDMPTQQ-------QDMAQFIHIFSKFYP----E-----------------EDIR--QPD--TSTRVSQWL---------------LH-------NRKL---GKPD

                                                                                                                                              HSVAV-REAGLKRLSSGCHLKDFGDLLAEVVSRAVSDGYSCVTL---GGDHSLAIGTISGHARHCPIHLSFD

                                                                                                                                           QCIA-IIELG-GEVELDIEGF-AVYFAPGFLDAITTAIHDPKPVVSISWGG--IAAMNRAFLDAAALGVTVLAA-------------DFP---VL----ACG---TG

                                                                                                                                       NG----ATPVYVSTWENHSVFMDGFKDIRTYRGLLSDMEKA---PEFSIFILHA--EWKQIAAVMKRRC------LFCSVV----------------GKDEDN--RVLS

                                                                                                                                           DNVLRIATR--WQ-HYVKDL-VELVPVTFVKELEVALLENRADIAVHS-KDVPV------FPQGL----GLV-I----KRLLP-------GIECRTRELLAALNH

                                                                                                                                             DVIIGA-R--AMHTLDKTLGSEIRDSVALEQSIEFIR-PIAGVIG----GSSSVAIQVQNLLQLFDIPQFLRV----PSD-NYG

                                                                                                                                          ADPGDAFLVPYYPAFRDLRWTGVQLIPIHIT--AVK---YENVKGLILTNPSLDKDTLKSVLSFTNQHNIHLVCD----AEILDE---------DLNDDV

IRKNTLKILRRILDRDH----P-HATASEA-------EEQVERAVEIYKEFFNSLGIPYLITAFDT---------IGTVH--NL--GQ-FA-TCYGLSDIA----------------------------IAIESGLCLPPD-QVVIVPMEAELSRLEAFRVHLDDRDIAGRKYYEWEMRGVPLRVEIGPMWC-ECGMDVEEKVR-------------------GREA

        MKIYG--IY--MDRP---------CRRF-HKEDAHRTLVLVRSVISR-----FS--PCIPDLPDAHFNIS-HSG----------RWVIGAFDSQP----GIDIEKT---------------------------------SLESKT-SDLLAKDKQTFY-----------------HLW-MKEIKQ------------------LPDSHSP

                                                                                                                       WTLTG----------------PFHVVAYDFGAKRNILRMLVCRLTIVTSAEDV----LKMNPDGIFLSNPCDYITAIQKFLET----DIPV--HGIHR----------------------------PEA

                                                                                                   DHK--SCE-------------DL---QI-----DRT-----LGQALCIADIQHEVIANLLYTKIIKCGVTPKNIIDAFNGGISLVNYTGH-WG-HFGTTHVKQLAQTGTV-------IAST-----DQ-----------MNE

                                                                                                                                           ATKSVLMLGSGFVTRPTLDVLTVTVALDVLDAEVAK----HDLVISLIPYTF---TV-KSAIRQKDAGITVMNEI-------------------------------GLD

                                                                                                                                            EFMKVLVIGEHAAWKAAQSVETVFVAIALLDF---AQ--KIDLTIVGPEAPLVKGVDTFRAAG----LKIFG-----PTAG-EGNAHRIVIEEFLD-------EE

                                                                                                                                              KNIIVTGFINFHYVYNHVHVTVLDKDIADLVDKLAAK-ADAIVHY--ATNFIGTYTLLEAARKYDIRFHHV-----------STK-----------TI--SN

VQTRM-----CAPPVGLP------PPPEEE----------------------------------------RPLTGAWLLSDE-------RPL------------------------------------------------GSPPVHIGIADAAKVAVEAIRRVILSVNFQALFRR-----VAAVIHH----SAGTEHVATRAG----VPQ-VIYFGRV--------------IG--TTV

KN--Q--VAYFGEDMNIH-HVTWHMDF--KGE-----FWVHHQLTARFDFERLSNWLDPVDE----------------------------------------------------------------APLT--EFP----------VD---------------GVA-HVMLGRQ-GD----GK

         MKIL------------PNLNMLG-------TLDQIHEIMQTFVKQGNLD-----------------------------------------------------------------------------------------------------VELEFFQTEIIDKIQESVGSDYEGIIIN-GAFTSIAIADAIMLA---GKPCGGV----------------------------ALM

AGAQNMRELISQMGVINDAVSSELANASSI-------LDIDKKVAETMRSG-------------------------------------------AGSLIPWI-----RIG--------AM------RC---------KVIPNER-------------------------------LTP---------------------------------------------------FTVGD

                                                                                                                                            EGDEVITPTWVSTLNIVLLGANPVVVDHIEAA--I---PQTKAIIPVHYPADLDAIYALGERYG---IPVTAIVVTD---------ERICSLP--------LFP

                                                                                                                                              IVIVLDGIYSVAFLNDLLVGIVQYGMTALGTDTARK-EAVMVIVTDGESDNHRLKKVIQDCEDENIQRFSI------------KFEI-KSISE--------IV

                                                                                                                                           SDKVVAIIV-SEAVQTMLPAFDPIMMESLVAEHLGVLKRRNIDGVVLFGFTGIT---E-MLAH-----WQSFASV-----------LP-----------TPET