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EDVKGFFASRESLDMEQYLVLDYYLESVGDIETALAHFCSEQSTFRLVHAAKVIDYEVIEELEQLSYPVKHSETGKIHACRVTIAHPHCNFGPKIPNLLTAVCGEGTYFTPGVPVVKLMDIHFPDTYLADFEGPKFGIEGLRDILNAHGRPIFFGVVKPNIGLSPGEFAEIAYQSWLGGLDIAKDDEMLADVTWSSIEERAAHLGKARRKAEAETGEPKIYLANITDEVDSLMEKHDVAVRNGANALLINALPVGLSAVRMLSNYTQVPLIGHFPFIASFSRMEKYGIHSKVMTKLQRLAGLDAVIMPGFGDRVMTPEEEVLENVIECTKPMGRIKPCLPVPGGSDSALTLQTVYEKVGNVDFGFVPGRGVFGHPMGPKAGAKSIRQAWEAIEQGISIETWAETHPELQAMVDQ

    VDKYE---PSKKRDIIAVFRVTPAYTIEQAAGAVAAESSTGWADLSAKAYDFHDMGD----------------GSWIVRIAYPFHAFEANLPGLLASIAGN-IFGMKRVKGLRLEDLYFPEKLIREFDGPAFGIEGVRKMLEIKDRPIYGVVPKPKVGYSPEEFEKLAYDLLSNGADYMKDDENLTSPWYNRFEERAEIMAKIIDKVENETGEKKTWFANITADLLEMEQRLEVLADLGLKHAMVDVVITGWGALRYIRDLAGLAIHGHRAMHAAFTRNPYHGISMFVLAKLYRLIGIDQLHVGTA------GKWDVIQNARILRESFYSIKAAFPTSSGGLHPGNIQPVIEAL-GTDIVLQLGGGTLGHPDGPAAGARAVRQAIDAIMQGIPLDEYAKTHKELARALEK

   MGYW----VPKDT-DLLALFRITPQVDPVEAAAAVAGESSTACDMYRAKAYRVDPVP-----------------EQFFCYVAYDLSLFEGSIANLTASIIGNV-FSFKPIKAARLEDMRFPVAYVKTFAGPSTGIIVERERLDKFGRPLLGATTKPKLGLSGRNYGRVVYEGLKGGLDFMKDDENINSQPFMHWRDRFLFVMDAVNKASAATGEVKGSYLNVTAGMEEMYRRAEFAKSLGSVIIMVDL-IVGWTCIQSMSNWCDMILHLHRAGHGTYTRQKNHGVSFRVIAKWLRLAGVDHMHTGTAVGKLEGDPLTVQGYYNVCRDAWASLRKVMPVASGGIHAGQMHQLIHLF-GDDVVLQFGGGTIGHPQGIQAGATANRVALEAMVLA-ILRDAARWCGPLRAALDT

    TYYEYQ---TKDTDILAAFRVTPGVPPEEAGAAVAAESST-LDRYKGRCYRIERVEK----------------DQYIAYVAYPLDLFEESVTNMFTSIVGNV-FGFKALRALRLEDLRIPPAYVKTFQGPPHGIQVERDKLNKYGRPLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENVNSQPFMRWRDRFLFCAEALYKAQAETGEIKGHYLNATAGCEEMIKRAVFARELGVPIVMHDYLTGGFTANTSLAHYCGLLLHIHRAMHAVIDRQKNHGIHFRVLAKALRMSGGDHIHSGTVVG----ERDITLGFVDLLRDDWVSLPGVLPVASGGIHVWHMPALTEIF-GDDSVLQFGGMTLGHPWGNAPGAVANRVALEACVKA-IIREACKWSPELAAACEV

  KLYTPDYT---PKDTDLLAAFRFSPGVPADEAGAAIAAESSTGMDRYKGKCYHIEPVEE----------------NSYFAFIAYPLDLFEESVTNILTSIVGNVFGF-KAIRSLRLEDIRFPVALVKTFQGPPHGIQVERDLLNKYGRPMLGCTIKPKLGLSAKNYGRAVYECLRGGLDFTKDDENINSQPFQRWRDRFLFVADAIHKSQAETGEIKGHYLNVTAPCEEMMKRAEFAKELGMPIIMHDFLTAGFTANTTLAKWCGVLLHIHRAMHAVIDRQRNHGIHFRVLAKCLRLSGGDHLHSGTVVGKLEGDKASTLGFVDLMREDWASMPGVLPVASGGIHVWHMPALVEIFG-DDSVLQFGGGTLGHPWGNAPGATANRVALEACVQA-ILREAGKWSPELAAALDL

KM--GYWYQV----KDTDVLALFRVTPGVDPIEAAAAVAGESSTAADLYRAKAYKVDQV-----PNNP---------EQYFAYIAYELDLFEGSIANLTASIIGNV-FGFKAVKALRLEDMRLPLAYLKTFQGPATGVILERERLDKFGRPLLGCTTKPKLGLSGKNYGRVVYEALKGGLDFV-DDENINSQPFMRWRERYLFTMEAVNKASAATGEVKGHYLNVTATMEEMYARANFAKELGSVIIMIDLV-IGYTAIQTMAKWADMILHLHRAGNSTYSRQKNHGMNFRVICKWMRMAGVDHIHAGTVVGKLEGDPIITRGFYKTLLLPWASLRKVMPVASGGIHAGQMHQLIHYL-GEDVVLQFGGGTIGHPDGIQAGATANRVALEAMILA-ILREAAKTCGALRTALDL

KDRLYTPDY--VV-RDTDILAAFRMTPGVPPEECGAAVAAESSTGLDRYKGRCYDIEPVED----------------NQYIAYVAY-IDLFEESVTNMFTSIVGN-VFGFKALRALRLEDLRIPPAYVKTFVG-PHGIQVERDKLNKYGRGLLGCTIKPKLGLSAKNYGRAVYECLRGGLDFT-DDENVNSQPFMRWRDRFLFVAEAIYKAQAETGEVKGHYLNATAGCEEMMKRAV-AKELGVPIIMHDYLTGGFTANTSLAIYCGLLLHIHRAMHAVIDRQRNHGIHFRVLAKALRMSGGDHLHSGTVVGKLEGEREVTLGFVDLMRDDDWSMPGVMPVASGGIHVWHMPALVEIF-GDDACLQFGGGTLGHPWGNAPGAAANRVALEACTQA-VIRSACKWSPELAAACEV

 QSSRYVLKEEDL-GGEHVLCAYIMKPGYGYVATAAHFAAESST-TRGVDALVYEVDEA-------------------RELTKIAYPVALFDAMIASFLTLTMGNNQGM-GDVEYAKMHDFYVPEAYRALFDGPSVNISALWKVLGRPGGLVVGTIIKPKLGLRPKPFAEACHAFWLG-GDFIKNDEPQGNQPFAPLRDTIALVADAMRRAQDETGEAKLFSANITADDPEIIARGEYVLETFHVALLVDGYVAGAAAITTARRRFDNFLHYHRAGHGAVTSPQKRGYTAFVHCKMARLQGASGIHTGTM--------SSDRAIAYMLTQDWGGMKACTPIISGGMNALRMPGFFENLGNANVILTAGGGAFGHIDGPVAGARSLRQAWQAWRVPVL-----REHKELARAFES

                                                                                                                                                    LAKRIIACL--DVKDG--DPVELGKFYSEIGIDELVFL--DI-SVEKTMLELVEKVAEQID---------IPFTVGGGIH---DFETASELILRGADKVSINAV-ENPSLITQIAQTFGQAVVVAID-AK---RVDG-GILLRDWVVEVEKRGAGEILLTYD-------TEMIRFVRPLTT--------LPIIASGGAKMEHFLEAFLAG----DAALAASVFHFRE-----DVRELKEYLKKH

                                                                                                                                                   SLAKRIVPCLD--V-HAG-DPVEAARAYDEAGADELVFL-DI-HEE---RAILLDVVARVAERVF-----IPLTVGGGVR----SLEDARKLLLSGADKVSVNAV-RRPELIRELADHFG-AVVLAID-AR---RGD--GLHAVEWAVKGVELGAGEILLTYD-------LRLTRMVAEAVG--------VPVIASGGARMEHFLEAFQAG---AEAALAASVFHFG------PIPKLKRYLAEKG

                                              VPD----------------------------------------GL--TAQQNCG-----------------DFL---PGY--------SA-TK---KIT------PLVSS---MDT-----EAGMAIAMALTGGIGFIH---HN----CTPEFQANEVRKVK-----DYPASLLCGAAIGTHE-DDKYRLDLLAQAGVDVVVLD---FQINMIKYIKDKYNLQVIGGN---------------TAAQAKNLIDAGVDALRVG-----SRP-ATAVYKVSEYARRF-----GVPVIADGGINVGHIAKALALG----STVMMGSLLAATKGSIHKFVPYLIAGIQHSCQD

                                                                              KEI------IT--NFK-AE---------GN-------LHTIR--------VTMA----------------NAVPVFAQSGD-------DRYDNVDKMIIKEADVLHAL--INNVEEKKLLEYVKWLRDRIIKL-RVREYAPIFHIDVIGDIKAMADYIQTLAEAA-HLRIEG-Q-AMRDLRAELDGRGVDAELVADEWCN---------EDVKFFTDNK----GHMVQIKT----PDLGGNNIADAIMYCKAN-----GMGAYCGGT-TNRSAEVTTNIGACGARQVLAKPG--MG-----DE--MVKNEMNRVLAL

                                                                                                                                           ERYENLQLNREGAFVPFVT---DPGIEQSLKIIDTLIDAGADALELG--VP---GVTPAQCFEMLALIREKHP-----TIPIGLLMYA---GIDAFYARCEQVGVDSVLVAVP--ESAPFRQAALRHNIAPIFIC--PPN---------ADDDLLRQVASYGRGYTYL--------ALP--LHHLIEKLKEY----HAAPALQGFGISPEQVSAAVRAG---AAGAISG---II--AELRSFVSAMKAASRA

                                                                                                                   KITKSLIPSE--------TQ--TKNIS---------PFLSS---MD------ESQMAIAIAKEGGIGIIH---KN----MSIEAQRKEIEKVKTY------CKLRVGAAVSID--DTIERVEELVKAHVDILVID---RIIELIKKIKTKYNLDLIAGN---------------TKEAALDLISVGADCLKVG-----PGVPITAICDVYEACNNT-----NICIIADGGIFSGDVVKAIAAG----DSVMIGNLFAG-SGKLKDILTQLKGGLMSG-INSKFV

                                                                                                                       DDIPDL-LEQ-VDISTK-IGELS----SS---PIFINA--MTGGTYEINKSLARAASQAGIPLAVG---SQMS---ALRLSYEIVRKENP--------NGLIFANLGEA---TAAQAKEAVEMIANALQIHL---ALKRIEQICSRVSVPVIVKEVFG------------SKASAGKLYEAGAAAVDIGTA--------ASLAEIRSEFP-------ASTMIASGLQDALDVAKAIALG----SCTGMAGHFLKADSGLLEEIQLILEELKLIMTV

                                                                                                                  AKYYNEY-PGL----NVNL---VKF--SEIN--LK--PLVSA---MQS-----GEKMAIALAREGGISFIF---GS----QSIESQAAMVHAVKNFKR------YLVGAGINTR--DFRERVPALVEAGADVLCIDGF-WQKITIGWIRDKYKVKVGAGN---------------DGEGFRYLADAGADFIKIG------RG-ATAVIDVVAERNFEETG-IYIPVCSDGGIYDYHMTLALAMG----DFIMLGRYFARFAGKLKDNVEASLNKVKST

                                                                                               YNEP-------------------NEYL---IPSN----KFQ-----SEIN------PLVSA---MQS-----GEKMAIALAREGGISFIF---GS----QSIESQAAMVHAVKNF-----ELVYLVGAGINTR--DFRERVPALVEAGADVLCIDGF-WQKITIGWIREKYKVKVGAGN---------------DGEGFRYLADAGADFIKIG------RG-ATAVIDVVAERNFEETG-IYIPVCSDGGIYDYHMTLALAMG----DFIMLGRYFARFAGKLKDNVEASLNKVKST

                                                                                                                                                     ALRIIPCL--DIDGG--DPVEMAVRYEEEGADEIAILDI---PEGRAFIDSVKRVAEAVS---------IPVLVG-GVR---SLEDATTLFRAGADKVSVN-AVRNPQLVALLAREFG-STVVAID-A----NGE--GLDAVKWAKEVEELGAGEILLTDV--------ELIRRVADSVR--------IPVIASGGARVEHFYEAAAAG---ADAVLAASLFHFRV-----SIAQVKRYLKER

                                                                                                                                            MFK------DGSLIPYLT---DPDKQSTLNFLLALDE-YAGAIELG--P----GFKLREAFWIVKEFRRHS------STPIVLMTYIY--GVRNFLAEAKASGVDGILVV--LPHAKEFTEIAREEGIKTVFLA--------------TPDERLKVIDDMTTGFVYLVS-IP----TYDLLRRAKRICR--------NKVAVGFGVSKRHVVSLLKEG---ANGVVVGSALVKI-EFLKKKVEELLG

                                                                                                                                          AKLK--------PIIAINF--TYIATGKRALEIAKAAEKVYTIVVAP----QL-------VDLRMIAESVE---------IPVFAQHI----DPIVLPEAVKEAGAVGTLLNH-RMILADLEAAIRRAGLMTMVCS---------------NPAVSAAVAALNPDYVAVEVSKA----KPEVITNTVELVKKVN---EVKVLCGAGISTGEDVKKAIELG---TVGVLLSG--AK---DPEKAIWDLVSGI

                                                                                                                                         MAGLK-------INPFGLA-APTT------SSSMIRRAFEAGWGFALTK--TFSIVEKTAAYWCQSVTELKADFP-----DNIVIASIMCSKNDWMELSRKAEASGADALELNLCG-VRNICRWVRQAVQIPFFAKLT--PNVT-------DIVSIARAAKEGGADGVTAT----IRPI-LRAVTTIARALP-------GFPILATGGISAESGLQFLHSG----SVLQVCA--DFT------VIQDYCTGLKALLYLK------DGQ

                                                                                                                                                    AELLLGVNIDH-------DPVQAAFIAEQAGADGITVH---REDR-TD--RDVRILRQTLD---------TRMNLEMVTE----LAIAVETK---PHFCCLVLD--KMRDACKRLADAGIQVSLFI---------------DEEQIKAAAEVGAPFIEIHTYADA----EARIAKAATFAASL-----GLKVNAGHGLTYHNVKAIAA---IPEMELNI-HAIIGRMTGLKDAVAEMKRLMLEARG

                                                                                                                                                     LPMLQVALDN---QTMDSAYETTRLIAEE-VDIIEVG-TI-CV--GEGVRAVRDLKALYP--------HKIVLADAKIADA-GKILSRMCFEANADWVTVICC-ADINTAKGALDVAKGDVQIELTGY------------TWEQAQQWRDAGIGQVVYHR--VAWGADITAIKRLSDMG---------FKVTVTGLAL-E-LP-FKGI----PIHVFIARSIRDAASP-VEAARQFKRSIAEL

                                                                                                                                      HSPGKAF--RAALTKENLQIVGT----------NANHALLAQRAGYQAIYLSGG--ST---DVLTDIRRITDVCS---------LPLLVDADFGSSNVARTVKSMIKAGAAGLHIEDQV-MVDRIRAAVDAKTFVIMARTDALAVEG------DAAIERAQAYVEAGAEMLFPI-------TELAMYRQFADAVQ--------VPILANILF---TTDELRSAH----AMALY----SA----------------------GTQKSVLYESI

                                                                                                                                      RISREMMK---------SVYFIMNT-------DPVTVVQKALKGGATLYQFR--EK---LTGRIKFAEKAQAACREA------GVPFIVNDD-----V-ELALNLK---ADGIHIGQEDANAKEVRAA--IGDMILGVAA---------------TMSEVKQAEEDGADYVGLG-IY---VQ-VSLIEAVRR--IS-------IPIVGIGGITIDNAAPVIQAG---ADGVSMISAISQA-EDPESAARKFREEI-GR

                                                                                                                                         LGF--TTL-----NRVLMG---HTGLGAERLAAFYAERARHGVALIVSG--GIA-GGAMLQ-HHRTITEAVHQEG------GKIALQILHLIDNFARCAQLAREAGYDGVEVMGSLIAVEVVRAVRERVGFIIIYRLS-MLDGG-----TFATVELAQAIEAAGATIINT-----RGAF--WVTRKLKGHVS--------LPLVTTNRINPQVADDILSRG--------------AD------------------------------GRAD-EI

                                                                                                                                                VTN----PVVVALDY-------R--AL--FV-IDDCRLKVGK--------T---FGPQFVRELQQRGF------DIFLDLFHDIPNTAAHAVAAAADLGVWMVNVHAS-GGARMMTAAREALAPLLIAVTV---MTLS-----DYAERLAALTQKCGLDGVVCSAQ----------EVRFKQVFG-------EFKLVTPGIRP--TPEQALSAG---VDYMVIGRPVTQSVDP-AQTLKAINASLQ

                                                                                                                                                       LVVPAI--DLFRG--DPVELVEKLIEEGFTLIHVV--L-NSGENL--PVLEKLSEFA----------EHIQIGGIR----SLDYAEKLRKLGYRRQIVSVL-EDPSFLKSLR-EIDVEPVFSLD-VAL------EEIDPVSLLKRLKEYGLEEIVHTE--QEH--DFSLTKKIAIEAE--------VKVLAAGGISENSLKTAQKVETNGLLGVIVGRAFLEG------TVEV-KRYA

                                                                                                                                  MIDV-----------------YIDNAA--KPHLSEKEIEEFVLKSEELGIYAVCV-----------P-YHVKLASSIAK--------KVKVCCVIGNKTSVKVKEAVEAVRDGAQELDIVWNL-VVEELKEIFRETPSVHKVIVE--Y--LN-----EEIKKAVEICIEAGADFIKTTTL--------EEVRLIKSSAKG------RIKVKAS-GIDLETAISMIEAG----DRIGT--SGIS-------IAEEF---------------------LKR

                                                                                                                    HRIFFKPK----RKVDISTD----LGS---HVD--PFYVSA--TALCK-EGEKDVARGCGQGTKVPQMIS---TL-------CSPEEIIEAA-PSD-----KQIQWYQLYVN-RKTDDLVKNVEKLGVKALFVTV--LTWKDIEELKKKTKLPIVIKG---------------RTEDVIKAAEIGVSGVVLSPI--------EVLAETMP--LENL----KLEVFVDGGVRRGDVLKALCLG---AKGVGLGRPFLYA-NGVEKAIEILRDEIEMSMRL---------DLL--DLSTL

                                                                                                                                                    KKLYISDVTLGSHQYTLDDVRAIARALDKAKVDSIEV--GDGLFGRHTDLEYIEAVAGEIS--------HAQIATLLLPG--GSVHDLKNAYQAGARVVRVATHC-EADVSKQHIEYAGMDTVGFLMMSHMIP------EKLAEQGKLMESYGATCIYMAD----MSDIRDRMRAFKAVLKP------ETQVGMHNSI------V-VEEG---CDRVDAAPLE---------------AVAERLG-------------DLYTLMD

                                                                                                                                         MGRF----NL----RVVLA---TRQRSQPHAAIYYSQRTT-PGGFLITE--ATG--DTPGIA-WKPIVDAVHAKG------GIFFCQIWHIVNDFRLAARNAMEAGFDGVEIHGIDFPLEIVDAVAKEIG-RVGIRLS-PFDTNP-----A-GLYMAESLNKYGILYCHVIE----ARM--HTLMPMRKAFK--------GTFISAGGFTREDGNEAVSKG----DLVAYG-WFLA----NPDLPKRFQV--------------------DAPL

                                                                                                                                                       RLILAMDL---MNRDDALRVTGEVREY-IDTVKIG--Y---LSEGMD-IIAEFRKRFG---------CRIIAAFK-NEKICRATFKAG----ADAIIVHGFP-SVRACLNVAEEMGREVFLLTE----FIQ-----GAADEIARMGVDLGVKNYVGPSTR------PERLSRLREIIGQ------DSFLISPGVG---DPGETLR-F----DAIIV-RSIYLADN-PAAAAAGIIESI

                                                                                                                                          SRV--DKFS-SDIIVSPSILS---NF--KLGEQVKAIEQAGCDWIHVDVMD-----TIGPLVVDSLRPITD---------LPLDVHL------PDQRVPDFIKAGADIVSVHCETIHLHRTINQIKSLGAKAGVVLNGT------------PLTAIEYVLDAVDLVLIMSV---IESQ-VKKISDLRKICAERG---LNPWIEVDGGVGPKNAYKVIEAG---ANALVAGSAVFGAPD--YAAIKGIK--------------------KRPE

                                                                                                                                           MG-KF-EL----RVVLA---TRQRSQPHAILHYSQRST---GLLIGE--ATV--DVPGIA-WKPIVDAVHAKG------GIFFCQIWHIVNEFRVAARNAIEAGFDGVEIHG-LIALEIVEAVANEIG-RVGIRIS-PFDTNP-----TAGLYMVESLNKYDLAYCHVVE----RME---SLVPMRKAYK--------GTFIVAGGYDREDGNRALIED---ADLVAYGRLFISN----PDLPKRFE---------------------LNAP

                                                                                                                                         VGAVT---------RVFMA---TRLRSTPLMGEYYRQRA--SAGLIISE--ATQ---PGLIA-WKKITAGVHAED------GRIAVQLWHIVNDFRQAVANAREAGFDLVELHSLH-VLEVVDAVCNEWS-RIGIRVS-PIDN-----PNEEALYLIEELAKRGIAYLHMSE---GGPYSEAFRQKVRERF--------HGVIIGAGAYTAEKAEDLIGKG----DAVAFGRDYIA----NPDLVARLQK--------------------KAEL

                                                                                                                                                     MVRVKICG---------TNLEDALFSVESGADAVGFV--FY---YIS-PEDARRISVELP-------PFVFRVGVFVNE--EPEKILDVASYVQLNAVQLHGE-EPIELCRKIA-ERILVIKAVG--------NE----RDMERALNYRE--FPILLDT-------FDWSLILPYRDRF---------RYLVLSGGLNPENVRSAIDVV--RPFAVDVSG-VEA---KDHDSIKMFIKNKGL

                                                                                                                                          MTTLE--AFARRAALIPYLT---FPSREGFLQAVEEVLPYADLLEIG---Y----GMSVQGALELVREVRALT------EKPLFLMTYVL--GPERFFGLFKQAGATGVILPDL--EDPGLVRLAQEIGLETVFLL---------------STARIATVVRHATGFVYAVS-----------LV---RI-KAR-----ALPVAVGFGVSKATAAQAAV------DGVVVGSALVRAGRSLAPLLQEIRQGLQ

                                                                                           HHH------HM---------------IE-EA--------PVR----------------DVAIEHTN--KPFATPDDIKKLCLEARENRFHGVCV---NP--------CYVKLAREELEGT------DVKVVTVVGNETRTKAHEAIFAVESGADEIDMVINV-VYEDIRSVVESVGKVVKVIIE-TCYLD------EEKIAACVISKLAGAHFVKTATA--------EDVHLMKWIVGD------EMGVKASGIRTFEDAVKMIMYG---ADRIGTS-SGVKVQ-----------------------RYG

                                                                                                                                 SRQ--PIIS-ERIL--EFNNITAIIAEYKRKS-----DPIEYSKFMER-YAVGLSIL----EEK-SY--ETLRKIASSVS---------IPILMKDFIVKESQIDDAYNL---GADTVLLIVKILELESLLEYARSYGMEPLIEIN--------------DENDLDIALRIGARFIGINS----EIN-KENQRKLISMIPS------NVVKVAESGISEREIEELR---KLGVNAFLIGSSLMRN----PEKIKEFIL

                                                                                                                                       SPGQARA----AKENPLQIVGAI---------NANHALLAQRAGYQAIYLS-GG-ST---DVLTDIRRITDVCP---------LPLLVDADFGSSNVARTVKSIAKAGAAALHIEDQV-MVDRIRAAVDARTFVIMART-DALAVEG-----EAALDRAQAYVDAGADMLFPEI------TELSMYRRFADVAQ--------VPILANILF---TTDELRSAH----AMALY----SA--MN-----------------------ELYESI

                                                                                                                                            ISL------KRFATITA----------DYSFAKLFADEGLNVMLVGDSL-VT--ADIAYHTAAVRRGAP--------NCLLLADLPAYATQAFENAATVMRAGANMVKIEGG-WLVETVQMLTERAV-PVCGHLGKVQ--GRGD-EADQLLSDALALEAAGAQLLVLEC------VPVELAKRITEALA--------IPVIGIG------------NV----DGQILAK---NFLGDIRAAVRQYMAE---------GV-----------GEEH

                                                                                                                                         GSL--SLP------RVIMA---TRSRTGRLQQIYYGQRA--SAGLIISE--ATN--TPGIEAGWKGVVEAVHAKG------GRIALQLWHIVEDYRQAAQRAKRAGFDMVEVHAALPPLEVVDAVAEVFG-RVGIRLT-PFTD-----DEPEAFYLAGELDRRGLAYLHFNE----DITYEGFREQMRQRFK--------GGLIYCGNYDAGRAQARLDDN----DAVAFGRPFIA---NPD-LPERF---------------------RLGAA

                                                                                        AMLA-----WDALG---------------------------GA-----------------RPVQAYDSH--SL-DGVKLATERAVTAAELGFRAVKT---KIGYP--QDLAVVRSIRQAVGD-------DFGIMVDYSLDVPAAIKRSQALQQEGVTWIEE-QH--DYEGHQRIQSKLNVPVQMGEN-WL-----------GPEEMFKALSGACRLAMPDA------GGVTGWIRASALAQQ-----FGIPMSSHLFQE---A-HLL--AAT-AHWLQRLD--LA-IEP------FEG------------------LP-GVGI

                                                                                                                                         MGRF----DL----RVVLA---TRCRANAALAEYYAQRTT---GFLISE--GTM--HVPGIA-WKQVVEAVHAKG------GFIFCQLWHVVEDYCLSALNAIRAGFDGIEIHG-LILKQVVEGVVSAIGSKVGVRVS-PATD-----SDPLGLAVVGMLNKLQLAYLHVTQ----R-EEAKLMKSLRMAY--------NGTFMSSGGFNKELGMQAVQQG----ADLVYGRLFIAN----PDLVSRFKI--------------------DGEL

            VNGAVTELD---------------------------------------------------------------GKPVS-------DLI---------------------------IARYQK-RA------------RRTPSQQAHVTN-VKDNPVQIAADAAEGAWRGFDEQETT-----ARYAP--FNAIALLVGSQVGR----PGVLTQCSLEEA----LKLGMLGH---TCYAETISVDDTPWSKGFLASSYGLKMRFTS--SEGYA-KS---YLEARCIYITKAAGVQGLQNGS----GVPGI-AVLAENLICSSL-----DLECASSN-----LL-MQFL---PGTDFIS-SNEDAED------F--YN--IQ-LKV---VREEDVIA

                                                                                                                              PL-PEPP-VP----KE--A-LRPGLSVIAEVKRQS-----DPVEAALAYARGGARAVSV---LTEP-GGSL-LDLKRVREAVD---------LPLLRKDFVV---DPFMLEEARAFGASAALLIVALLGELTGAYLEEARGLEALVEVH--------------TERELEIALEAGAEVLGI-------IN-LETPR-LGRLARKRG--F-GGVLVAEGYSRKEELKALE-----GFDAVLITS-LMRAP-DLEAALRELVG

                                                                                                                                           QI--TLRN----RFYQV---CIGAKPGFQSAHRSVKAEGGWAALNTE--YCS---ARIVRNLKAMTDEVHKYG------ALAGVELWYVQQFYVDAAKRSRDAGFDIVYVYG-LPWLETLEKVKHAVDCAIATRFG-VDTQIE-----VDGQKFVEMADS-LVDMWDIT--G-HT----PWVKLVKQVSK--------KPVLGVGRYTDP------------------------------EKMIEIVTKEQG---------RYD----DIRV

            DNGLIVEL---------------------------------------------------------------DGKRR--------DMI-------------LEA--AKAAQM---------MRAR------------RTPSNQCHVTN-LKDNPVQIAADAAEAGIRGFSEQETT-----ARYAP--FNALALLVGSQCGRP----GVLTQCSVEEA----LELGMRGL---TSYAETVSVDDTPWSKAFLASSRGLKMRYTS--SEAS--KS----LESRCIFITKGAGVQGLQNGA----GMTGIRAVLAENLIASML-----DLEVASAN------TLMQML---PGTDFIF-SNFDAED------F-----NLQ-LMV---VTEAE-IA

                                                                                                                                RDI--------------------RIDSTL--SPRATEEDVRNLVREASDYGFRCAVL---TP--------VYTVKISGLAEKLG------VKLCSVIGAPLEVKLVEAQTVLEAGATELDVVPHL-VYREVSGIVKLAKAVVKVILE-APLWD-----DKTLSLLVDSSRRAGADIVKTGGDP------V--VFRLASLAKPL-----GMGVKASGGISGIDAVLAVGAG----DIIGT--SAVKV--------LE-----------------------KS--LV

                                                                              KPLL-------------------DKLR--ID----GNLVRLL--EWQ-----------------------EAIPLFGQSGDD-------RYIAVDK-ILKGVDVLPHA--INNVEEKKLREYVRWLSDRILSL-RSSPRHPTLHID-IGDPVRCAEYIASLEKEA-PLYIEG--DALTAITKELTRLGSGVKIVADEWCN----------QDIVDFTD--GS-CH-VQIKT----PDLGIHNIVDAVLYCNKH------GEAYQGGSA--RTVHVALAA----RPRLIKPG--GFD----------VFNEN-RTIAL--LQT

                                                                                                                                       MKN--------------PIIALDF---AS-AE--TL--L---EPLFVKVGM------YQ----EGPSIVKQLKERNC------ELFLDLLHDIPTTVNKAMKRLASLGVDLVNVHAA-GGKKMMQAALEGLRPSLIAVTQ---IEKS------TVVHYSKQAEESGLDGVVCSVH---------EAKAIYQAVSP------SFLTVTPGIRM--TPAIAREKG---SSAIVVGRSITKAEDP--KAYKAVRLEWEGI

                                                                                                                    RILF--------------------ILGFK--IS--PIMIA---TAMQK--GEYATARAASAAGTIMTLS---W---------SSVEEVASTGP---------GIRFFQLYVY-RNVAQLVRRAERAGFKAIALTVDTLSWKDVAWLQTITSLPILVKG---------------TAEDARLAVQHGAAGIIVSTI-------M-ALEEVVKAAQG------RIPVFLDGGVRGTDVFKALALG----AGVFIGRPV-S---GVKKVLQMMRDEFEL---MAL--SHI

                                                                                                                                                     RALMDLTTL-NDDDT-DEKVIALCHQAKTNTAAICI-----------P-RFIPIARKTLKE---QGTPEIRIATVTN--IDLA--ETRAAIAYGADEVDVVFPY-GFDLVKACKEACNVLLKVIIE--E--LK-----ALIRKASEISIKAGADFIKTNAT-------PESARIMMEVIRDMG---KTVGFLPAGVRTAEDAQKYLAIADAWAYRFGASSLL---------ALL---------------------GHG

                                                                                                                                      NLT-EKFLRIARRG--KSIILAY--HG-----DPEYILRLARDAGFDGVVF---QRG-----AEKY---YDGSV-----------PLILKLAN----SVEEAVSLG---ASAVGYTI-MFELARIKRDAVKFDLPLVVWSY-PRGG-KV------AY-AARIALELGADAMKIKYTG------PKTFSWAVKVAG-------KVPVLMSGG-FLKQVEGVLE---AGALGIAVGRNVWQRRDA-LKFARALAELV

                                                                                                                                                       HIDHTLL-KPTATLEEVAKAAEEALEYGFYGLCI-------------SYVAWVRARYPHA------PFRLVTVVGQEKEVKALEAALACARGADEVDMVLHL-LEAEVRAVREAVPAVLKVILE-TGYFS------EEIARLAEAAIRGGADFLKTASL---------EVALLVRVAQG------RAQVKAA-IRDRETALRMLKAG----SRLGTS-SGVA-------LV

                                                                                                                                           NL---------RGVMAALL----LDKASLRRLVQFNIQQGIDGLYVGGSA--LSERE--QVLEIVAEEGK--------KIKLIAHVGESQ-Q--ASAKRYG---FDAVSAV-TP-HYRAIIDS---DGLPMVVYNS--GVKL-------TLDQINTLVTLPGVGALKQTSG------DLYQMEQIRREHP-------DLVLYNGYDE----FASGLLAG----DGGIGST-YNI-------MGWRYQGIVKALKEGDIQT--------AQK

                                                                                                                                                     MRVKICGI----------TR---LEDALLAEFALGFV--AP----I----APEAARAIGEALG----PFVVRVGVFRQPPEEVLRLMEEAR---LQVAQLHG-EEPPEWAEAVGRFY--PVIKAFPL--EG--------ARPEWADYP----AQALLLD-----AY-PRAWAKPLLATGR---------RVILAGGIAPENLEEVLALR---YALDLASG-VEE----SAEKLRALFARLASLR

                                                                                                                                  SMA-DKA-ARIDAICEK----RILPVI--TIARE-EDILPLADALAAGGIRTLEVTLRS----QH-GLKAIQVLREQRPE--------LCVGAG-VLDRS-FAAVEAAG----AQFVVTPGI---TEDILEAGVDSEIPLLPGI---------------TPSEIMMGYALGYRFKLFPA----EISGGAAIKAF-G---GD-----IRFCPTGGVNP--NVRNYMA--LP-VMCVGTTW-MLD--ARIEACSAEAIALLD

                                                                                                                                     FEN---LGR-------TPQMGWNSHFYCGINE-QIIRETADALVLAYQYVNID-DCWAEY--VP--GIKALADYVHAKG------LKLGIYSDGSLDHEEQDVKTFASWGVDYLKYD-NC-VMERYTRMSNAMNIFFSLCEW-G--------------NPATWAGR-MGNSWRTT---WGSSR-ADENDQWAAYAG-------GGWNDPDL-EV-RSFSIWAL-A---KAPLLIGC-VRSMS--------KLSN-SE------VQEVW---LW--NR

                                                                                                                                     MKSAE-SIL-----TT-GPVVPVIVV---KKLEHAVPMAKALVAGGVRVLEVTLRT----EC--VDAIRAIAKEVPE--------AIVGAGVLN----Q--QLAEVTEAGAQFAISPGL---TEPLLKAATEGTIPLIPGI---------------TVSELMLGMDYGLEFKFFPA----EANGGKALQAIAG---SQ-----VRFCPTGGISP-ANYRDYLALK---VLCIGGSW-LVP--DRITKLAREAVEGA--KL

                                                                                                                                                     QINVSFEF--FPPR----LWNSIDRLSSLKPKFVSVTYG---SG-DRTHSIIKGIKDRTG---------LEAAPHLTATPDELRTIARDYWNNGIRHIVALR--YASDLVTLLKEVADFDISVAA--HPEA------KSADLLNLKRKVDAGANRAITQFFFD-----SR-FRDRCVGID--------VEIIPGIL-AMDMVKILSR--EGV--DFHFY---AEM------SY-AICHTLG

                                                                                                                                    LSV--KLPG---LDL-KN-PIIPACF---------GFGE--DLNK--LGSIMVKA-TTLHPFPGLEEKLPWLNENFPE--------LPIIANVAGEEADYVAVCAKIGDAAVKAIELNI-AFAAALVKACKAVSKVPLYVKL--SPNVT-------DIVPIAKAVEAAGADGLTMI----AI-V-LKLIHQVAQDVD--------IPIIGMGGVNAQDVLEMYMAG----SAVAVGA---DPF-----VCPKIIDKLPELMDQ

                                                                                                  ALLDL--KAR------------SI----LLG-SA------------------IPIAWTLAS---GDTKRDLDSAVEMIERRHNRFKVK---LGFR--DDLIHMEALSNSLGSK-------AYLRVDVAWDEQVASVYIPELEALGVELIEQPRE--NTQALRRLSDNNRVAIMADE---------------TLASAFDLARRSVDVFSLKL------GGVSATQKIAAVAEA----SGIASYGGTMGTS-----VALQLYTVPSLGCELIGPFV--HEPL-----EIR-QV---------------GV-HGM--TL

                                                                                                                        GEN-------------RNHLEV----LSERVKIIAEFKKAS-----SLEDFIRMYDELADAISIL---TE-KH-DP--AFVRAARNLTC---------RPILAKDY-DTVQVKLASSVGA-----DAILIIAILQIKEIYEAAEELGMDSLVEV--HS----------EDLEKVFS---IRPKIIGINT----IK-NV--LWELLPLVPD------DTVVVAESGIDPRELKDLR----GKVNAVLV--SIMKAENP-RRFLEEMRAWSE

                                                                                                                                  MKQ----VVSI--GDIN-LPFVLFGGM--NV-ESRDLAMRICEHYVTVTYVFKAS---DK--RGPGLEEGMKIFQELKQTFG------VKIITDVH-----EPSQAQPVAD-VVDVIQLPAFL-RQTDLVEAMAKTGAVINVKKPQFV-----------SPGQMGNIVDKF-VILCDR------VVDMLGFSIMKKVSGN-------SPVIFDVLAR-----AVG------LAGLFI----PLAK---------MKAIDDL--LDTS

                                                                                                                                           HMF--------RGVGTAIV----PELDL-YELVRYQLENGVNALILGT-SP---TVNEDEREKLVSRTLEIVD----KIPVIVGAGTNSTEKTLKLVKQAEKLGANGVLVVTP--LYQHYKYISERTDLGIVVYNV---GVN--------LPETAARIAADLVVGIEAN-------PDIDQIDRTVSLTKQA----RDFMVWSGNDD-------FLCAG---GDGVISVV-SNVA------PK---VEAE--SG------NLEK------VHRKL

                                                                                                                                          EVLG---KRQS---PLLIG--TGLNG--KGDLALARAATKAGIPFVLS--TA---NM----SIEDLARQCD---------GDLWFQLYVHREIAQGMVLKALHTGYTTLVLTT--FNWEALRWLRDLWPHKLLVKG---------------SAEDADRCIAEGADGVILS------IS-MEVLAQSVAKTG--------KPVLIDSGFRGSDIVKALALG----EAVLLG-ATLYG-TGVDEVLTLLKAID-R---LAQ---YL----------NE

                        RCS------------------------------------DGVAPA-------LAADN-------------MLK----LDKL-----------AKIE-------SELL-------------------LEVAWTLA---SGDTARDIAEARHMLRRHR-VFKLK---IGAN--QDLKHVVTIKRELGDS-------ASVRVDVYWDESQAIRACQVLGDNGIDLIEQ--SRINRGGQVRLNQRTPAPIMADE--E------------SVEDAFSLADGAASIFALKI------GGPRAVLRTAQIAEA----AGIGLYGGT-GT---L--HAFL--TLRQLGTELFGPL----EPPQ----YRD------------------RT-LGL

                                                                                                                        LAQNE------QPSTRHF-DAL-----GARTAFILECKKAS-----DPARIAAIYKH-YASAISVL--TD-EK-SF--NFLPIVSQIAP---------QPILCK-I-DPYQIYLARYYQ----ADACLLMLSV-QYRQLAAVAHSLEMGVLTEVS-------------EEQERAIALG---AKVVGINN----ID--RELAPK----LGH------NVTVISESGINYAQVRELSHFA----NGFLI--ALMAH--DLHAAVRRVLLG-------------NKV--AGAI

                                                                  RHL-------NQ-SIGN-----------------------NK--------VELLGE-----------------------------EMLGYL--FYVLTPESVVALAEAA--YGFKDFKLK--GG----LRGEDEIAAVTALSERFP-----DARITLDPAWSLKEAVALCR--Q--VLAYAED---GAGREVMAEFRRSTGLRTATNM---------------DWRQMGHAIQQSVDIPLADP----HFWTMQGSVRVAQMCNEW-----GLTWGSH-SLA----THVAAAA-PGNITIDTHW--IW--EPLQ----IKG-VE----KKPGLG

                                                               GGLV-VGK----------ASN----------------DRAV--------------ID--LS---ADLIG-----------------SIPIAWTLAS---GDTARDIDSALEMIERRHNRFKVK---LGAR--QDLEHIRSIVKAVGDR-------ASVRVDVGWDEQTASIWIPRLEEAGVELVEQPRA--NFGALRRLTEQNGVAILADE---------------SLSSAFELARHAVDAFSLKL------GGIA---NTLKVAAVA---AGISSYGGTDST-----AAALHVY-ATLLCELIGPW----QQDLE-IKD----HL---------------LG-LGV--DL

                                                                                                                                                      MLIIGER--NGKRAPAPVQEWARRQEEGGARALDLN--V-KVS--AMEWLVEVTQEVSN---------LTLCLDSNIK----EAGLKKCK----RAMINSTN--KVEKLFPLAVEHGAALIGL-----TGIP------TRLAFAMELVAAA-LYIDPLI-ANVA--HAPEVLKTLQ-IKMLA---PAPKTVLGVSINRTFLAMAM---ACGLMSAIA-------------CDEALIETAA---SFV

                                                                                           SQVT------------------------LLDL--------RQHF------------DPRQVQVSTLL-SILMEVEQVLESARKAKAAGSTRFCMGA--WPH---YLEQMVQGVKAMG----------LEACMTLGT---LSESQAQRLANAGLDYYNHNL--ERLDTLEKVR-DAGIKVCSGG-------LGV---KDRAGLLLQLANLPPESVPINM-----DVDAFDFIRTIAVARIM-----TSYVRLSGRE------TQAMCFM--ANSIFYNPEE-----KDLQ-------FR--LG

                                                                                   LAG-YEA-------LHD-QHLL------------VELY--------MLGG-------------------TDYTVS---VNSPEEMAADAENYLKQGF-TLKIK---VGKDD-TDIARIQEIRKVGSA--------VKLRLDAGWRPKEAVTAIRKMEDALGIELVEQKD--DLAGLKKVTDATDTPIMADE---------------TPRQAFEVLTRSADLINIKL------GGISGAEKINAMAEAC-----GVECMVGSGIT-----HFA---SKRNIRFDFDAPL---FN----SGSTI----------------GKPG-------LG

                                                                                                                                              IRTHH--HKWAMLTA----------DYSTARIFDEAGIPVLLVGDSA-SI--DELIPLVRGVVRGAP--------HALVVADLPSYPTAALAAATRFLKGGAHAVKLEGG-RVAEQIACLTAAGIPVMAHIG---FT--PGD---EQTIADAIAVAEAGAFAVVME------MVPAELATQITGKLT--------IPTVGIG------------PN----DGQVLVKRY--ADVG----------------------------------ELR

                                                                                                                                            MF--------TGSIVAIV----VC-RSLKKLIDYHVASGTSAIVSVGTES-LN--EHADVVMMTLDLADGR-------IPVIAGTGAATAEAISLTQRFNDSGIVGCLTVTPY-LYQHFKAIAEHTDLPQILYNVPDL--------------LPETVGRLAIIGIKEA-----G------NLTRVNQIKEL-----DFVLLSGDD--------LMQLG----HGVISVT-ANVA-------ARDMAQM-KLAAEGHEA---------RVIN

                                                                                                                                                    LTRRIIACLD-VRTLVLGKPVQLAQKYYQQGADEVTFL-NI--------TPMLEVLKQAAKTVF-----VPLTVGGGIKD-IPALEVASLYFRSGADKVSIGDAVYAASPIETISKAYGQAVVISVD------VYVDTKNKVWELTRACEALGAGEILLNCYD------LELIEHVKDAVK--------IPVIASSGAGVPEFEEAFLKTR---DACLGAGMFHRGE-----TVNDVKEYLLEHG

                                                                                                                                     LEN--GLAR-------TPPMGWLARFRCNCISEMLFMEMADRIAWRYKYINID-DC-AAK---LVPGIKALADYVHARG------LKLGIYGDTTLDRVEQDAQTFAEWGVDMLKLDG---QAQGYPQMARALNIVYSCSPAYQG-----------GLPNYTLLGE-ICNLWRNY--VLSI-WFFTNQ-VLQPFAG-------GHWNDPD--IIGRQMALWT-IM---AAPLLMSTDL--IS-----------KIQN-------RII-EVFFSR

                                                                                                                                                    TKTKIMGILN-VTPNNVESAVTRVKAMMDEGADIIDVG-GVELN--RVL-PVVEAIVGFD----------VKISVDTRSE---AEACLKLG----VDIINDQGLYDH--RMFQVVAKYDAEIVLMHNG----NGNRD--EEMLTSLLAQAHQA-IWLDPGI-----TEEAEVMR----LVAT------EYPVLLATSVTAATTAYGIM---KGVRAVRV-------------NVELNAKLAK

                                                                                                                                                    QRGLTVVLDK---------GLP--V-YLKVCIDFVKFGW-G-----V---R--DVVKEKINYYKD---WGIKVYPGFEAYSGKFDEFLNECEKLGFEAVEISD-DISLEERNNAIKDNGFMVLTEVGK-DKQLT-----DDRIKLINFDLDAGADYVIIE-----FD-KENELDVL--VDI---------KVIFEAPQK---QVAFILKFGSV-NLANI---AF-------DEVISLETLRR-----GLRG

                                                                                                                                         KTVT--KNLIEGMPKIIVSLMG--RDSVKAEALAYRE---ATFDILEWRDH--IAS--SVLTAARVIRDAMP--------DIPLLFTFYLT---NRAAIDSGL---VDMIDLELFTGDVKATVDYAHAHNVYVVMSNHD----PS------EMVSRLRKMQALGADIPKIAVMPQ---VTLT-ATE-MQYA--------DRPVITMSMV---IRLAGEVFG---SAATFG---AVQA------AVNDLRSVLMILHNA

                                                                                                                                        LNS----------DLEFI-EA----------NGLSARIVQEAGFKGIWGSGLSN-AS--QVVEVLEFSDASD----------VPILLDAYGNFNNARRLVRKLEDRGVAGACLEDKL-FALKIKACKDSQTFCIVARVEAFAGWG------DEALKRAEAYRNAGADAILHSKAD----SD-EAFKAW-NNQ---------GPVVIVPYYK-TPTDHFRD-----GVSVIW--HNLRASA----------------------IV--KEI

                                                                                                                           RQWQS---ER----------------ELYIICDVCLCCGVSVSRLAAVAVNYAKAGAHCVAPS--DM----ID--GRIRDIKRGLINANL---HKTFVLSYAA-GRGLARRALERDMSEGADGIIVKSTFYL-DIMRDASEICDLPICAYHVEYAMLHAAAGVV-IAFESHQGFLRAGARLIITY------------APEFL

                                                                                                                                                    EKFLVIAGPC--A-ESEELLLKVGEEIKRLSEFVFKSS--DK---GHGLEYGVKALRKVKEEFG------LKITTDIHE-----SWQAEPVAE-VADIIQIPAFL-RQTDLLLAAAKTGRAVNVKKGQFL-----------APWDTKNVVEKL-IYLTER------VVDFR----SLPIMKQ------WAKVIYDAIF---R--AAVAVG---CDGVFM-LPL--------SQLEGI-EA---EVKY

                                                                                                                                                      MELYLDTS---------DVVAVKALSRIFLAGVTTNPS-----KKPLDVVLPQLHEAMGG-------QGRLFAQVMATAEGMVNDALKLRSIIAIVVKVPVTAEGLAAIKMLKAEGIPTLGTAV---------------GAAQGLLSALAGAEYVAPYVN---DGGSIQTVTDLHQLLKMH---APQAKVLAAF--TPRQALDCLLAG---CESITLPDVA-------QQ----M----------ISYPAV

                                                                                                                                  PA-AKR---EAID---KDDRVLVIVGP--CS-HDLEAAQEYALRLKKLSSIIMRA---EKINDP---QSARQLFVNLTNIG-------LPIGSEMLD-----TISPQYLAD-LVSFGAIGARTTESQLHRELASGLSFPVGFKN-TDG-----------TLNVAVDACQAA-CFVILNYD-------AKSVAEAKAQL-PA----GSNGLMIDYKVN--DCEQIAN--GENAITGV-----WET

                                                                                                                                      RR----VSK--LLSERVLLLDG--AYG--VVLKVHRSYIES---GSDVILT---FGA----IVRNAVRIARRAA--GE------KLVFGDIG-FYENFRETVEIMVEEGVDGIIFEFSDELKAAVLAAREVSDVFLIAHMT-RSLG-------TDPANFAITFDELDIDALGI-----PEEI-LPIFQELSQYTD--------KFLVVEP--FAVHIDSYYELG----VNIFGG---TPE-------VKLFRKVLG

                                              LSQRPR-----------------------------------------------------------------------------ETTLS-----------------NDLVLPIM--RIPEKHLAREIERIANAGIRSVMTF------SH-LVARMSRICKQTVP--------EMIVMSDTCFTLENLGKQAVVAAAAGADFIAPS--AAMDGQVQAIRQALDTAIMSYTKQMNPMN------REAIRESLLDEAQGADCLMVKA----GAY-LDIVRELRERTE--------LPIGAYQSL------GS--RA-----DLISYF-ALDL--------KILR

                                                                                                                                     LDN--GLAR-------TPTMGWLHRFMCNISEKLFMEMAELMV-WKYEYLCID-DCWMAP--QA-HGIRQLANYVHSKG------LKLGIYADGSFGYYDIDAQTFADWGVDLLKFDG-C-LADGYKHMSLALNIVYSCE-LYM--WP-----FQK--P-YTEIRQ-YCNHWRNF--IKSI-WTSFN-QEIVDVAG-------GGWNDPDLVIG-VQMALWA-IM---AAPLFMSNDL--IS-----------ALQD-------QLR-EV

                                                                                                                                                     AAKIAPSMLS-----FANLAAEADRMVRLGADWLHMD--IMD---TIGAPVIQSLRKHTK---------AYLDCHLVTN---PSDYVEPLAKAGASGFTFHIEVSR-DNWQELIQSIGMRPGVSLRPGT-----------PVEEVFPLVEAPVELVLVMT---MPEM---EKRALRKKYP-------SLDIEVDGLGP---ID-AASAG---ANCIVAGSSIFGAAE----PGEVISKS

                                                                                                                         PYSAEDVVKL--AQ--AAKMW---RLGKGYINSLGA----------TGGQALQQAKAGIEAVYLSGW----AA-SVPAVVERINNTFR-YF------LPIVADAEAGVLNAFELMKAMIEAGAAAVHFEDQL-AIQKLVAARLCAPTLLVARTDADAAHAG-----EQAISRGLAYAPYADLVWCET-PD------LELARRFAQAIHYP-----GKLLAYNC-----FQQQLS--D---GYKFQ-AGI----NM----------------------AAAFVS

                                                                                                                                         TTFA---NAK-----PMNA-VHC--MT-IEDLEELK---ASQAGAYITK--SSTLEKLGFDYYLDYVLKNQNAQ------EGPIFFSIAENI-ALKKIQES-DF---GITELNLT--LLKEVFTFFT---KPLGVKLP-----YFDL---VHFDIMAEILNQFPLTYVNSV----KPTA-A--VRAFYTRLKP------EIQIIGTGGIETGDAFEHLLCG----TMLQIGTALHKE---GPAIFDRIIKELEEIMNQ

                                                                                                                                  PA-VAH----IHK----DDRLLVVIGP--CS-HDPVAAKEYATRLLALREIVMRV---EKINDP---RIARKLLLDINDSG-------LPAAGEFLD-----MITPQYLAD-LMSWGAIGART-ESQVHRELASGLSCPVGFKN-TDG-----------TIKVAIDAINAA-CHIILNYS-------AKHVAEVKEGL--KAG--LP-QVMIDFDVC--VCQQIAG--GEKAIIGV-----LV

                                                                                                                           RLVRE--VLTVD--------------ELGIITDVALDDGISIDVLVRQALSHAEAGAQVVAPS--DM------MDGRIGAIREALES---AGHTNVRIMAYSAKNSDEALHEVAADLAEGADMVMVKGMPY-LDIVRRVKDEFRAPTFVYQVEYAMHMGAIGWL-VILESLTAFKRAGADGILTY-------------------------------------------------------------FAKQ-------AAEQL

                                                                                                                                                    RKPIIAGNW--MH-KTLAEAVQFVEDVKGHVPSVVCA----PF-------LFLDRLVQAADGT------DLKIGAQTMH----FADSPVMLKDLGVTYVILGHRAETDETVNKKVLTRGLIPIICC------SLEEA---VVASQVEKALA---AVIAYE----KS--STEDANSVCGHIRSSRLF-AAIRIQYGGSVKPDNIRDFLAQQ----DGPLVGA--------EPASFLQL

                                                                                                                                              MRD--KG--DGLYVGGENFMLSTEEKKEIFRIAKDEAIALIAQ---GSVN---EAVELGKYATELG----------DCLSAVTP-SFPEIKHYYDTIIAETSNMIVYS--NMGIEQFGELYKNPKVLGVKFTA--------------DFYLLERLKKAYHLIWAGFD----------MMLPAASLGV---------DGAIGSTFN-------------------------VN-------GVRARQIFELTGK-KEA----------LE-DL

                                                                                                                                           KYL-----NGY-AVPAFN-----HNA----ETIQAILEVCPVILAGTPG------FK--IALEEIYALCSAYSTTYNMPLALHLHHES-----LDDIRRKVHAGVRSAMIDGSH-NVKLVKSVVDFCDCSVEAELGR-SA-FL------TDPQEAKRFVELGVDSLAVAIG--PK-IDFQRLAEIREVVD--------VPLVLH-VPD-EFVRRTIELG----VTKVVATEL----DAMKEVVRNKINVC

                                                                                                                                       TRK------------LILAGNW--MH-KTISEAKKFVSLLVNEL-IVVCP-----------F-TALSEVGEILSGRN------IKLGAQN-----FYEDSPLMLQEIGVEYVIVGHRKEDDEFINRKVKAVGMTPILC-------TLEEK---LTFCVVEKQVREG-VVIAYE----RV----QQAQEVHAFIRKSEMY--IRILYGGSIKP-DNFLGLIVQK---IDGGL

                                                                                                                                                    MRPLVMGNW--LN-GS-RHMVHLVSNLRKEL-VAIAP-------------MYIDMAKREAEGS------HIMLGAQNVN-LNL---SAAMLKDIGAQYIIIG-RE-LIAKKFAVLKEQGLTPVLCI------TEAEA---EVCARQID---V--AVIAYEP-----WA---QAQAVHKFIRDAKVD-IAVIIQYGGSVNASNAAELFA--QP-IDGAL-GA--------KADAFAVIV

                                                                                                                                                     RVPLIGFAG--TLMLTDALVPYLVGQVVAGAQALQLFESHA----FALPYIRDVAKQVKARLREAGLAPVPMITFAGHF--ALEELAQA-----GYEVVGLDWTVAPKKAREC--GKTVTLQGNL--DPCALYAS----EIGQLVKQMLDDF-YIANL------PDMDPEHVGAFVDAVHK---------------------------------------------------------HSRLLRQ

                                                                                                                                                      AEGV-CR--EH--LLPIQRADFVGILRAMRPVTIRLDPGCRL--EIYNMQVRAIIEAAIAVSEEGSSVIPEIMVPLVGKEELSLIREEVVKTAYTVGTMIEVPRAAVTADSIAQKA-DFFSFGTNDLTQ---YA---EGIGELVRIAVTKGLKMGICHGG-------PATIGFCHKVG---------LDYVSC-SPF--RVPVAIVAAA-------------------------------HASIK

                                                                                                                                     NK---IVK--GNID-KPFVLFGGN---V-ES-RDA-QVCEAYVKVT-YVFKAS--FD----PG-EEGLKIFQELKDTFG------VKIITDVHE-----IYQCQPVAD-VVDIIQLPAFLARQTDLVEAA-KTGAVINVKKPQ-------------FLS-QGNIVEKI-IILCDRG-----NLI---VDLGFSV--KKA--SKGSPVIFDVQVT--LARSGLA--VGIAGLFL-AL---PLS-----ALEGFVSQK-AIKS

                                                                                                                                            VNT----AGEKIA-LTA----------ESSFAAL-DDAGVELLVGD----SL--RDC-YHTECVARGAK---------NAIVSDLPAYKEQAFAAAAEL-AAGAH-VKLEGG--WAETTEFLQ--RGIPVCAHIT-----KA-----QALLNDAKAHDDAGAAVVLEC-------VLAELAKKVTETV--------SCPTIGIG---------A---D---CDGQVLVKNF---QSV-QAAVRAYVAEV

                                                                                                                         TYSAEDVVAL--RR--AEWEQ-----DLEWVNALGA----------TGNMAVQQVRAGLKAIYLSGWQ---SG-SVPQVVRRINNALQR----VEN-APIVADGEAGALNVYELQKALIAAGVAGSHWEDQL-HIRTLTSARLAAPTVVIARTDAEAAKNG-----EPCIARAKAYAPFA-DLIWM-PD-------LEAARQFSEVK-YP-----DQMLAYNC------------------------------LD--------FQK-----------AAE--TAT

                                                                                                                                         VNCGL----TFKDGVLGINI--GKN-GKDDYLIC-EKIYAY-AGYIAIN--IS-RT--ALDDLLTAIKNKQNDLQAHH-KYVPIAVKIALSEEELIQVADSLVRHNIDGVIAT---KSTEIIRRLSLELRLPIIGVG--G-----------DSVIAAREKIAAGASLVQIY------IKGPPLIKEIVTHI

                                                                                                                                                       ISTILD--VAADK-ILLYRNLLGLMQGRSLLFIRN--GHLMTIPEGILDGVMTGAIALYDLKVQKNSVYIVKP-KMHGQEVAFANKLFTRIELKMGIMDEERRTSLNLRSCIAQARVAFINTGDRT----KNQ-STP-IKAYERNNVLSG-QIGKGMWMPDL----MSQKGDQLRAGA---------NTAWVP--SPTAATLHALHYH--------------------------------QT----FNA

                                                                  IPA-------EDI----------------------KVT-----------AVLD--------AAEGSV---VP--------------CGVSVG--IMDTIPQLLDVVGGYLDEGYVRIKLK--IEP----GW--DVEPVRAVRERFG----DDVLLQVDAAYTLGDA-PQLARLDP-FGLLLIEQ-EE-DVLGHAELARRIQTPICLDE---------------SARAAADAIKGAVQIVNIKP------GGYLEARRVHDVCAAH-----GIPVWCGGGR------AL---SLPNFTLPGDTSA-RF--PFV-----GGH-----------TGPGL

                                                                                                                                        MK-RDL--LKARRGPLFSFEF---PKGE--LF--TL-ELKAFRPAFVSITYG--GST-ERSVAWAQRIQSLG-----------NPLAHLTVSRKEVAEVLHRFVESGVENLLALR--YAAELVALIRERYRVSVGGAA--HPESE-----SLEDLRHFKAKVEAGLDFAITQ----FN--HFGFLERA-RIG---------IPILPGI-----QVAELLEAG----EGVHFY---SPRM-------------------------------ER

                                                                                                                                               LERLGE-VVIGDGGFVFWTPAVRQLHREFLRA---GSNVMQT----TF-G--VNEAACDIARQVADEGD------ALVAGGVS-IFHQQLEVFMKKN---VDFLIAE---EAVWAVEALK-TSGKPIAATMC--DLH------GVSPGECAVRLVKAGAAIVGVSLQ---------TIKLMKEGL-ERL----KAYLMSQP--IQKYAREAYNLG----RYIGG----EPY------R--AIAEELAP--------------HGSWG

                                                                                                                                TDKLT----------------TTVVADTG--------------DIAAMKLY-DATTNP---------VTDKLAVNIGLEILKL-----VPGRISTEVDLDTEASIAKAKRLIKLY-RILILAST-QGIRAAEQLEKEGINCNLTLL---------------SFAQARACAEAGVFLISPFVG---ILP-VVSVSEIYQYYKEHG--YETVVMGASFRNI---ILELA----GCDRLTIA---------------PALLKELAES-EG----------AIE

                                                                                                                           RAWQTA-TLNA----------------SNLIYPIVA--RYGVKRLEEMLRPLVEEGLRCVLIF-----VPS-ADSPAIEAIHLLRKTFP-----NLLVACDVCLSRQRLAEVALAYAKAGCQVVAPS--DMMDGRVEAIKEALLVSVMSYKFA--LPPG----ARGALRAVDRDVREGADMLMVG-----MPY-LDIVREVKDKHP-------DLPLAVYH--VL-AMTAFRRAG----ADIIITYYTPQL-------LQ

          IGHRAP-LAVGQVFLP--DAQEACRCIVETEILA----YYIYGWRQV--------------------RPEIEQIIVGNNKGVSDEQFELDL--YIIRRRIAV--MEDIL-------RQN-------------RLGN------------------LRRHGTLNVAMNRIG-AKSDSG-EG---------ED-PARFRPN------------AIKQVA----------AEYLN-QCRELEIKV-PHSIEDLAQLIYDLDAKVTVKL------RS------GIGTIAAGVAKANADIILISG-----LP-EMGLSEVHQVL-TRL----RVRLRTDGGLKTGDIVIAAMLG----EEFGIGTASLIA--KVVNLFTFLAEEVREILAG-----LLH

                                                                                                                                         VKVL-GHK-TADGLPLGINL--GKN-AAADYAEGVRTLGPL-ADYLVVN--VS-----ELRHLLSKVLQERDAL--KGTRKPAVLVKIALTAQDKEDIASVARELGIDGLIVT---LSTQTIREMYAQGRIPIIGVG----------------------------------------------------------------------GVSSGDALEKIQAG----SLVQLYTAL-GP-----PVVVRVKRELEALLKER

                                                                                                                                         IGN----EL-----RAVIP---TRMRPNRWAVEYYTQRAQRPGTMIITE--GAF---PGVMVEWTKIFNAIHEKK------SFVWVQLWVYIKEYVQAAKNSIAAGADGVEIHS-LLTLEVVDALVEAIGEKVGLRLS-PGMSGGA--ETGIV-AQYAYVAGELLAFVHLVE----REYE--SNDFVYSIW--------KGPVIRAGNFA-PE-RE-----------------------SNPDLVDRLE------------------KGL----EEA

                                                                  IPL-------GKTLG--------------IEAA--------------------------VNASLLG------------------VEMLGYL--FFVMTPDAVVRLAEAY--YGFNDFKLKGG---LA--EEAESIVALAQRFP--------QARITLDPAWSLNEAIKIGKYLKG-SLAYAED---GAGREVMAEFRRATGLPTATNM---------------DWRQMGHTLSQSVDIPLADPH----FW---TMQGSVRVAQM-----FGLTWGSHSSLA----THVA---AAPGIAIDTHW-IWQEGEP---IKGLV-QV------------PEKP-------VEI

                                                                                                                                     GA-------------GKFVVGGNW---CN----GTLASIETLTKGV-VIVGV--------------PFIYIPKVQQILAGEANANILVSAEN------WTKHVGMLVDCQVPYVILGH-HESNEQVAEKVKVAGLKVIAC---TEAQRIAN----QTEEVVAAQLKAI-ILAYEP------KTATDQAQEVHQYIRKTENI-VTRIQYGGS-VNPANCNELAK-KA--IDGFVA----------DAAKFKTII

                                                                                                                                                                      FQKGDFKAMYKALRPMTVRLD-GCRLY-EIAKMQTRAVMEAAIEVKEETGIDIVPEIMIPV-EKELKFVKDVVVEVAYHIGTMIEIPRAALTADAIAEEA-EFFSFGTNDLTQF--YE---TGVGQLVEMAVKKG-KCGICHGG-------PSSVEFCHKVG---------LNYVSCS-PF---VPIARLAAA---------------------------------ALN

                                                                                                                                                    RHPVVMGNW--LN-GS-KEVVDLLNGLNAEL-VAVAP---------L----FVDLAERTLTEAGS----AIILGAQNTD----LNNSPAMLKEFGATHIIIG--E-FVAKKFAFLKENGLTPVLCI------SDAEA---AVCAR-LD---V--AIIAYE----KA------AQRIHAQIRAAEKS-VAVVIQYGGSVKPENAAAYFA-QP--IDGAL-GA--------DAKSFAAI

                                                 KKGKLP-----------------------------RTDLK------------------------------------KNRD-YPLA-------SK---DS--LLCGAAV------TREDDKYRLDLLTQAGVDVIVLD--SSQ-----NSVYQIAMVHYIKQKYP-----------------------------------------------------HLQVIGGN---------------TAAQAKNLIDAGVDGLRVG------GRPGTAVYKVAEYARRF-----GVPIIADGGITVGHVVKALALG----STVMMGSLLAATKGSIQKFVPYLIAGIQHGCQD-----KFE--------RTM

                                                                                                                                  SAK---------------PQPIAAANW-----------------------------KCN-----GT-TASIEKLVQVFNEHT--ISHDCVVAPTF---------HIPLVQAKL-VISAENA---IAKVSMPILKDIGVHWVILGYGET----------EVAQKVSEACKQGFMVIACIG---ET--VVLSQTSA-AL--KD-----NQVVLAYEPATPEQAQEVHLLLRAKLRILYGGSVN-------AANAATLYAKP

                                                                                                                                      AR-------------TFFVGGNF--LN-GS-KQSIKEIVERLNSI-VVICP-----------A-TYLDYSVSL--VKK----PQVTVGAQN-----YLKASVDQIKDVGAKYVILGHRHEDDKFIADKTKFAVGVILC-I--TL-EEKKAG---KTLDVVERQLNAV-VVAYEPAT----------DADIHASIRKFLSKLAALILYGGS-ANGSNAVTFKDKA---VDGF-----KP--------EFVDIINSRN

                                                                                                PTG-----------------------LQ--EA--DYL-KNFAEKLVLAKK-KGITMAQPRAGV---ALLDEHIELLRYLQDGGADFLPST--ID--ECPGVN-------------------------------------------------------FGVKGCRKVLEAVNLPLQARH---------------SRLLAEIIHAGGWTSNEGGGI---NVKSLLDWQYCDRLVGFY----VHINREPF---SNAVGITEALLAA-KNITVGY---GE----CG-QDIAALRCLEEQ--AYSKE-------VIKAE

                                                                                                                                         VRVLG---HKFDGLPLGVNL--GKNDAAEDYAEGVRVLGPL-ADYLVVN--VS-----ELRRLLTKVLQERDGL---RRVRPAVLVKIALTSQDKEDIASVVKELGIDGLIVT---LSTQTIREMYALTRVPIIGVG--G------------SSQDALEKIRAGASLVQLY-----------------------------------TAL--------------------------FWGP---PVVGKVKRELEALLKEQ

                                                                                                                                       LA-TTAQK------AGKG--AA--TIK-R-ASYRDLLFGT-GLFISGAIL------------EETLFQ--PMVNLLHNE---NIIPGIKVDKGLDGLAERCKEYYKAGARFAKWRTT-GLARYASICQQ-NRLVPIVEPE-IL---V------KVLSCVFK-LQVL-ALLKPNMV---TA--L--TVRTLRTVPP-----ALPGVVFLSQEASVNLNSINAL-GP-ALTFSYRA-LQAS-KAREVLLQRAE------------------------KYKG

                                                                                                                                 SAQLKFT-------------TVVADT-G-----------------DFHAIPATTNPS--------IK-NAIDKLFVLFGAEILK---KIGVSTEVDALDKDAMVARARRLIELY-ILIKLSST-WEIQAGKELEEHGIHCNMTLL---------------SFAQAVACAEAGVTLISPFVG--LDWH-EDPGVKSVTKIYNKKFSYKTIVMGASFRN-----TGEIKALAG-FLTIS----------------PKLLGELLQ----NA---DEK----SFR

                                                                  IMS---------LE---------GLTRE------KIL--------------LDC--QS----LIGI----------------ETVI--TAQT--VIGQMANSASTLWGAK-----LLKVK--LDNH---LISERMVAIRTAVPDA--------TLIVDASWRAEGLAARCQLLADLGVAMLEQPLAQDD-AALEN--FIHPLPICADE---------------TRSNLKALKGR-YEMVNIKLD-----GGLTEALALATEARAQ-----GFSLMLGCAI---S---LP-----PQVFADLDG----VEPALQTTGELH

                                                                                                                                                     GFEYAWI---DHY-----VYETLALIAEGTIKLGPGV--TNPYV-RSPAITASAIATLDELSN-----GRATLGIGP-PVSTIRDAIAMMRTLLIPIYMGAQ----GPMMLKTAGEISDGALINA---------------NPKDFEAAVPLI-VAAYTCCSINAAKMEV---K--IEALGE-----GVTQYVAGSPIKEKSIKL

                                                                                                                                                   APKFFVGGNW--MN-GD-KKLGELIHTLNGAK-VVCGA-----------S-IYLDFARQKL--DA-----KIGVAAQNC----YKVPSPAMIKDIGAAWVILG--GELIGQKVAHALAEGLGVIACI--GK-DEREAGI-KVVFEQTKAIADNV-VVLAYE----GKTA-Q-QAQEVHEKLRGKTVS-VATRIIYGGSVTGGNCKELASQH----DGFL-GA--LKP------EFVDIN--KH

                                                                                                                                                       ITTIMD--SVAADKVLGYRNWLGLNKGRSLMFVR---VGHLMTNEGIMDALFTGLIAIHGLKALINS-IYIVKPKMHGAEVAFTCELFSRVTMKIGIMDEERRTTVNLKACIKAARVVFINTGFLRTMKS-----QP-ILAYEDHNVDAG-QVGKGMW-MADM---VETKIAQPRAG-----------STAWVPSP-TAATLHAL--HYH------------------------------QVGL------------KRRAT

                                                                                                                                       KKA-------------GVGAFN------NNM---EFLQAVLEAA-VILAL--------------AMRALTLMAELAKEARVPVAVHLDHGSS-----YESVLRALRAGFTSVMIDKSHENVRETRRVVEAAGVTVEAELGR----DA-------NPEEARIFMERTADYLAVAI---PF--DHARLERIARLVP--------APLVL--IHP--IK-KAISL----GIAKI---DL-----AVKEVVKSRMEL

                                                                                                                                                    RKFFVGGNW--KNGRK--SLGELIGTLNAAKVEVVCA---PT--------AYIDFARQKL--DP-----KIAVAAQNC-----YKISPGMIKDCGATWVVLGHRHESDELIGQKVAHAGLGVIACI--EKLDEREAG---ITEKVVFEQTKVIVVLAYEP------TA-QQ-AQEVHEKLRGKSNV-VATRIIYGSVTG-ATCKELASQP----VDGF-GA-KP--------EFVDIN--KQ

                                                                                                                                      KMLFE--LEVKKI-ET---MPVVN---------P--EPKELEKMGFEIIITN--SY-YKDLR--KA-LGIHRDYN---------GIIEVD--SNR----EF-HRI---GVDIGTFLDIT-RAREAEEI---KEIPMNATIQ-GSTY-------DLRRYAARRLSSMNFEIHPIG---YR--DVVDIVISSKMALRP------DRPVHLFGAGHPIVFALAVAMG----VDLFDSASYAL-LAL--HNLWVIKEEIKRVKQA---------DERA-KLYS

                                                                                                                                       TQ----FNIVGY--GLKVVRVW--NDVFQ-IN-LQTLDYVVQSA-LIIPFVNN----A--QYRKYVQAVVSRYA--S----TAIFAWEL---IVQWATSVSQYVKSLD-LVTLGDEGLTDFAKNVQI--KS--DFGTFH---SWGTNY-----WGNGWIQTHAAACPCVFEEYG----AQ-PCTNEAPWQTTSLTTR---GMGGDMFWQWGD-YN-------------------------------------AIN

                                                                                                                                        LSDIAH-RI-AP--GKGILAA--ESTRR--YRQLLLTA--DRCIGGVIL-----------H-ETLYQFPQVIKSK------GGVVGIKVDKGLDGLSERCAQYKKDGADFAKWRCN--VLARYASICQQNGIVPIVEPE-IL----------KVLAAVYK--LIY-TLLKPNMVTPG----MA-TVTALRTVPP-----AVTGVTFLSEAS-INLNAINKC----ALTFSYA--LQASWEEYVKRAL---------------------------YTSS

                                                                                                                                     VFQW-----NIF----GAYAVVDPHNYGRYSPSDFETFWKTVASQF-VIFDTDNEY--MD--LVLNLNQAAIDGIRSAG----TSQYIFVEGNTWTNVNDNMKS---LTD-IIYEMHQY--RITSATQWLRANGKKGIIGE------GG-ADNVCEITGMLDYMAQNVWTGAIWWAAGPWWFSAYQQILPILTPYL

                                                                                                                     STS------YK-----LTR----------KF--------------------------------FVGGNWKMNGDYASVD--GIVTFLNASAD--N----SSVDVVVAPPAP---LAYAKSKL--KAGVLVAAQNCEISPAMIKDL--GL---EWVILER--GES------ALIAEKTVHALEAGIKVVFCIG--EK---VNFRQLQA--VSW-------ENIVIAYEP-AQEVHEWIRAFLKADATRIIYGG-VT------ADNAAELGKKP

                                                                                                                                       ELREAQK-------PGKGILAA--ESGRR--YRQLLFST--PKLISGVIL-----------H-ETLYQFAEILKKKG------IILGIKVDKGLDDLAARCAQYKKDGCDFAKWRCN--VLARYASICQSQRIVPIVEPE-VL--V-------TVLAAVYK--LVY-TLLKPNMV---TA--ALATVQALRTVPA-----AVTGVTFLSEAT-VNLSAINNV----ALTFSYA--LQAS-NELLKRAKA---------KYVAGS

                                                                                                                                   LN--YTI----KDRASG--GFA-LAV--QRLTD--FKVNAAKILSP-YASAVLL----DQQ------RQ-VE--NAVAK--------SCAIVAADDK-----INAQAVKRDGAKALKLLVL--NVKEFNELCHSNGLLSIIEPV-VRPP--FD----DAAKELG---DSGADLYKVEPYGK------A-SQRLNGHIN---------PWVILSDE---FPRAVRVAEAG-ASGFLARA-VWV--DVSAPKLQRLGE--DE

                                                                                                                                                    PQPIAAANW--KCNGS---------------------------------ESLLVPLIETLNAAT--FDHDCVVAPTF---------HIPMTKARL-QIAAQNA---ITRVSLQILKDYGISWVVLGRYGE-----------TNEIVAEKVAQAFHVIVCVG-ETN---VVLTQLAA-AQ--SK-----SRVVIAYEPATPQQAQEVHELLRAQLRILYGGS-VT------AKNARTLYQMR

                                                                                                                                                    RKYFVAANW-----------------------------KCN-----GT-LESIKSLTNSFNNLD---FDPVVVFPVS--V------HYDHTRKLLKSTGIQNV---SKFVSAEIAKDLNIEYVIIGFHET------------DEDVREKLQASLKAVVCFG-ESL---VITKQVKA-VD--ID-----NVILVYEP-ATPEQAQLVHKEIRA-IRILYGGS-VN------TENCSSLIQQE

                                                                                                                                                    PQPIAAANW--KCNG----------------------------SQQSLS-ELIDLFNST--SIN----HDVQCVVASTF-------TKERL--SH-FVIAAQNAEVSLPILKDF-------NWIVL----YGET------IVADKVAAAVASGFMVIACIG-ETL---VVTQIAAI-A---KKD----AKVVIAYEP--PQQAQEAHALIRAGLRILYGGS-VN------GKNARTLYQQR

                                                                                                                                                                   LVVESL-PW-KR----PDGVIL---DI-T---YVGEALTILRKEV-NNQ------AAVLGFVG-FATSMAKYIRYQADSGAQAVQIFDSW-SLPYLKQIVDSVNLPLILYASG-------------SGGLLERLPLTGVDVVSLDW------T---VDADGRRRLGP-----NVAIQGNVDP-IT-RINDTVKKA-GKGHILNL---------NFAH-FE-AKGLR

                                                                                                                            FP---VDLFEAP--DWVK---TV---------------GDLQGIIDH-LDLVDLGITGIYLTP---FRSPVD--K-LKTLIDRCHEKG------IRVMLDAVF-KRYLLDVATYWIRFDIDGWRLDANEIDHEFWREFRQEVKVYILGEI---------------HD--AMPWLRDQFDAVMNYPVLR------Q--MHVLHSYPN------NVAAFNLLG--KLLFLFQ------FTGSPCIYGDE----------------LIAL

                                                                                                                                                   KQGPTSVAYVE--VNN---NSMLNVGKY--NAFDVAVIF--AAHFNENV-QRVLDNQIRPLQQQ------GIKVLLSVLG--AFAKQLSDAVAKYGLDGVDFDD---FVHLVTALRANMDKIISLYNIGP--------------SR--DVSD-KFDYAWNP----GTQV-------G--ALP---------QLSPAAV-VADLARRTVDEG---YGVYLTY----RTA-----V--SFTRELYG

                                                                                                                            YI-HRSEV-------TPEW-------------------GDLKGVIDR-LYLEELGVTALYFT--PIFAS-ID--L-FRRLVDEAHRRG------IKIILDAVFVKEYLFDVARFWMEQGIDGWRLDANEVDHAFWREFRRLVKALIVGEIW--------------HD--ASGWLMDQFDSVMNYLVIR------E--TRARMLYPE------QAGLWNLLD--RLAVLFQ------YLGTPLIY---YGD-----EI--FYKELIR---RSWHAD

                                                                                                                                       ELI-ATVKKL-T--PGKGLLAA--ESIRR--QRA-MLEA-FEQYISGVIL-----------D-ETVGTFPEYLTARG------VVPGIKTDMGLDGYVKRASAYYKKGCRFCKWRNV--NAETLARYAILSGLVPIVEPE-VM-----T----VSEHVWREVVAAL-CLLKPNM------VVVHYTVMTLATMPA-----MLPGVMFLSQAS--ELNAINNS----FLSFSYRA-LQSS-AG-RRAFLHR--------KYKR--SDD

                                                                                                                             PFINVDVFQP------PAWV-----------------GDLQGVIDHL-HLS-LGVNAVYFT--PLFKDP----K-LKKLVDLCHERG------IRVLLDAVFNKYLLKAAEYWIRETGIDGWRLDANEVSHQFWREFRRVVKAYILGEV---------------HE--SSIWLEDQFDAVMNYNAVLD---ML---GKQLAGYPR------QAVMFNLLD--KLAVLFQT-----YFGTPCIY--YGDEV---------------LRQA-----LTAE

                                                                                                                                                     GFRYSYDMLGEAA-YMVSYQQAIHAIGKASRPGISIK---L----LHLYPRLKSLTLLARQY------DIGINID-LE-----LDLLEKLCFELWIGFVIQAYQKRCPLVIDYLIDLALMIRLVKG---RKV-----YTD--VSYLACAKKLIPQFATH------------NAHTLAAIYQL-----AYEFQCLGM-------PLYEQVLNRPCRIYA

                                                                                                                                                                                EAGISAIWLP---PSKGET---K-LVRLIQTAHAY------GIKVIADVVICHQWLWSYAAYLRSIGFDGWRFDVKGYGAWVVRDWLNWWGGWAVGEYW--D----------TNVDALLSWAYESGAKVFDFYMDE------A--QTVVSRDP--------FKAVTFVA-KYPAYAFIL----YEGQPVIF-RDFEEW-------KDKLINLIW------DNLIF

                                                                                                                                          YD-LRCYTLNNEKTLIMGIL-NVT-EVDAAVRHAKEMRD-GAHIIDI----GGE---RVVPMIQAVSKEVK---------LPISIDTY-----KAEVAKQAIEAGAHIINDIW--KAEP---KIAEVADVPIILMHNR--MNY----RNLMMIADLYDSIKIA-IILDPGI----LEAMR-NLEQLNVLG---------YPVLLG---TGATVCLI--KG----CEFVV---VKE--------SRMAKMMDAMIG

                                                                                                                                         FA---SLDL----------------------------------------------------------------------SHPHVMGILNVSLIDAVKHANLMINAGATIIDVGGE-RVIPVVEAIAQRFEVWISVDT---------------KPEVIRESAKVGAHIINDRS------EP--GALEAAAETG--------LPVCLMHM-VNRYFIEQIARCEKEKLLLDPGF--NYS----LARLAEFHHFN-AKE

                                                                                                                           VP-YLSLAG----------------RLPVPCFNV--HAG-------------MGS---------------KDI-NEPLPILMEAI-E-HR----KFAICMDC--TAEQLRETYCKWAHDYPIVSIEDQD--DFAGFAGITEALKTQIVGDD---------------NTERIKMAIEKACNSLLLKIN-----IGTSEAIASSKLCME-----NGWSVMVSHGET-TYIADLV---ALGS-QIKT---PCRG---------AKLNQLLRIEEE

                  EFMIAPTGA--EALRIGSEVYHNLKS-----------------------------------------------------------------------------------------------------------------EG---AP-----------------------------IQTAEEALDLIVDAI-GHDG----KVKIGLDC--TGPQLADLYHSLMKRYPIVSIEDED--DWEAWSHFFKTAGIQIVADD---------------NPKRIATAIEKAADALLLKV-----NGTLSESIKAAQDSFAA-----GWGVMVSH-----IADLVVG---LRTGQIKTG--PARS---------QL-LRIEEELG

                                                                                                                                       ELSDIAQ-RI-A--NGKGILAA--ESV-E-RQREILFTV--NINIGGVIL-----------H-ETLYQ--LFRNILKE---KGIVVGIKLDQGLDGLSERCAQYKKDGVDFGKWRAN-TLARYASICQQ-NGLVPIVEPE-VI--V-------KVLAAVYK---VY-TLLKPNM----TA-ATTALHRT--VPA------AVPGICFLSDAT-LNLNAINLC----KLSFSY-A-LQASWATQEAFMKRAV---------------------QYVH

                                                                                                                            LH--RVDLFQAP------DWVKD---------------GDLQGIIDHL-YLADLGITGIYLT--PIFRA---FEI-LKTLVKRCHEKG------IRVMLDAVFVKRYLLDVATYWIRFDIDGWRLDANEIDHQFWREFRQAVKVYILGLIW--------------HD--AMPWLRDQFDAVMNYPALR----RL---MHVLHSYPK------QVAAFNLLG---LLFLFQ------FTGSPCIY---YGEI--------------ALRK--FLTA

                                                                                                                                     GVITGD---DV-KVVAFAPVIVQFSNG--QGILGAISGAHHVHQMA-VILHTDHCA-KK--LP-DGLLDAGEKH-F---T------FSSHMIDENIEICSKYLERMSK-IGMTLEIELG--DVDYAYTELSKISPRFTIAA-SFG---V-------TPTILRDSQE--LNFVFHGG----SGSTAQEIKDSVSYG-----------VKMNIDTMIARLEKAFQELNA

                                                                                                                                               SIKSG-------WNW-----SFNTLKHN-MDIHDAGYTAIQTS--PINQNR---EQ-FKEMCAAAEEYG------IKVIVDAVI-QSYLKRFLERALNDGADGFRFDAKHIELPFWPNITNTSAEFQYGQIL------------DS--SRDAAYANY--MDVTASGIRS---------YAS-DVSA--------DKLVTWVE-IRLGWAVI-----RSGSTPLFF---GSA------LFEDITAVN-----------SNP

                                                                                                                                       ELI-ETAKKM-A--P-KGLLAA--ESTTA-RQYRALMLEC-GFEISGVIL-----------D-ETVYQFPQYLRRR------GVVPGIKTDCGLDGYIKRAKKYYAMGCRFCKWRNN-TLARYAILSQ-LCGLVPIVEPE-VM--V-------HVWSEVVS---VV-CLLKPNM----VP--AEYTVKTLAIPP------ALPGVTFLSMAS--ELNAMNNC----KLTFSYRA-LQSSWRAFMHRAK----------KYNRAD

                                                                                                                                          SDLQ--------FPIGLGTNA-------GG-TGVREAIRNGVTLDTA---I-----IG--RSEELIGEVLRE-F-----DVVIATKAANSPDFLKKSVDESLKNT-IDLFYI-K--AVNALNE-KKAGKIRSIGVSNFSLE-------------K--GLV-----DVLQG--LLNREAE--FFPYTKEHN-----------SFIPYFP-HIVLAWYLARP----DILIP---GA----KRADQLIDNIKTADVTLSED----IS---FIDKLFA

                                                                                                                                        SNGVE----------VIGLGTWQS--SP-AEVITAVKTAVKAGYRLIDTA-VY-----Q----EEGTAIKELLE----GVVELFITTKAWEAPGKLEGGLRESLKQL-VDLYLA-PA-VWRQFDAVYKAGLAKAVGVSNWN------------N-IS--L--LTPVHNSQVEL-LYFP--QHDHVDFCKKHN-----------SVTS-TLAQVLLRYALDRG----CAILP---SIQ--NRIKENF----EVFDFS-----TEEIAK

                                                                    VNN------------------------------LPQ------------GVSC----------AAN-------------------AAPLC-----GDPDDLILKLAD--MPGEKVAKVK--VGLY---RDGMVVNLLLEAIP--------DLHLRLDAAWTPLKGQQFAKYVN----IAFLEE---KTRDDSRAFARETGIAIAWDE--LR---------P---FAFV--AE-GVRAVVIKP----TLTGSEKVREQVQAAHA-----LGLTAVISSLT---LARIAAWL---PDTIPGLD---------------------------------------PGST

                                                                                                                                 NLA----------------ILPVPAFNVGF---AP-----------------------------ILNNKDALDLIQEAI-GYT-----KIEIGMDV--SGDQLRDMYMEFCKDFPIVSIEDQD--DWETWSKMTSGTTIQIVGDD---------------NPKRITTAVEKACKCLLLKV----N-GSVTESIDAHLLAKK-----NGWGTMVSHFIA-----DLV---GLCTGQIKTGA-PCRS--AK----YN-ILRIEEELG

                                                                                                                                                      GGIAIYWG-QNG-----TLTQTCST--R-YSYVNIAFL--IN-NP---T--SNGIRSCQIQG------IKVMLSLGYTLAVADYLWNNFLGAVLDGIDFDIEHGSTLYWDDLARYLSVYLTAAP---------------PFPD---LGTALFDYVWVQF----YNQYINNIINSWNRWTTS----NAGKIFLGLPAPP--LIILPEIKKSPKYGGVL---DDKN------YSSSILDSV

                                                                                                                                      VRY--GGD--------------------PN--DWYNILRQQAATIASAIWMP--V-WRDF--FNK--AQLRQAASALG----AGVKVLYDVVPVYGMFRDEFTNLRSQYGAGGFRFVRGYAPERVNSWMTDSASFCVGEL--WKGP-----NTASWQQIIKDWSDRAKCPVFDF-----KERMWKHG-LNGNWRE---------VAVTFVD----RYAYILTSP----GTPVVYDHMYDWG---------IRQLIQ

                                                                                                                                                   PFV-EPHIHLTQ-WALTHDDVKQRAWLQI-IQHVRTHV---DVSD-----LTALKAMLEVKQEVA-PW--DLQIVAFPGIL--NGEALLEEALRLGADVVGAIPHFEGVESLHKTFALADRLIDVHCD-IDDEQ----------RFVETVAALAVTASHTT-----------MH------LKM-----SGINFVANPL------------LE--NVCFGH-GTA-----QVLH-----------------LMGQI--FDALRRQ

                                                                                                                                           QLS----ISN---VFRAAM-YTSGY-PSVKEKVKETVEAAYVIIDWH-ILPNI---YKEEAKDFFDEMSELYG----YPVIYEIA--VTWNQIKPYAEEVIPVI-VIVGTSQD---HHAADNQL-ADPNVMYAFHF--THGQ--------LRDQVDYALDQGAAIFV-------TSEAQVWIDFMDERN-----------LSWAN-----------------------SL----------------------------------------TGG

                                                                                                                                           KAA--LAA--QVQIGCWS-----LSNPISTEVLGLA---GFDWLVLDGHA-----PNDISTFIPQLMALKGSA------SAPVVRVPT----EPVIIKRLLDIGFYNFLIPFV--ETEEAELAVASTRITILVQIESQ---------------NVDAIAATGVDGIFV------SH--QKAQ-HIFNRASAH-----GKPSGILA--VEADARR-LEWG---ATFVAVGLGVFRSA

                                                                                                                                                                                                                         PVQVMGVLNVDLDDAVKHGLAMAAAGAGIVDVGGE-RVIPVVKELAAQGITVSIDTM---------------RADVARAALQNGAQMVNDSG------A----DPAMGPLLAE-----ADVPWVLMHW-VRADLLASVADAVPARLVLDPG---WAI----LHALPELVATGAWM

                                                                                                                                                                     NFL-GK-VDDIAAAITHVWLP---PASQ--RLYK-LKSLIGALHGKG------VKAIADIVINDVELVEWLNWLKAIGFDGWRFDAKGYSADVAKIYIDRSEPSFAVAEIWTS---LAY----QHRQELVNWVDKV-ATTFDFKLNV---------PGMIGWWP--------AKAVTFVF---MQYAYI-TH----PGTPCIFDHFFDW---------LK-EEIDRL--IIIVK---------GNDY

                                                                                                                                          PRFTI-EMVIR-RPILTDA--GGVLSPERSIEIQHLLG---SDIVMA---DE-----RSMRWAKRSRDAFD-AE-----NAALFGIQQGSVFLRQQSADALAEIGFDGYAVGLAVEMFRVLDFSVPMLPKPHYLMG---------------KPDDIVGAVERGIDMFDCV-----TRSGEHNIAFYQQLMQKDSIS

                                                                                                                               YHYLG----------------VLPTPMMNI--NGPNL-------------------------------SNEEGFEVIIEI--EYV----KDVVLAMDAASTTDEMIKFYEELVSKYPIISIED-EN-DWDGFKKLTDVL-KVQLVGDD--------------NTQKLSEGIEGIANSILIKV----NQGTLTETFEAIEMAKE----A-GYTAVVSHE---STSDIAVA---TNAGQIKTG--LSRT----------KYLRIEDQLG

                                                                     RVG--SWN----------------TWPDR-------------------------------VI--AP----------------LWCAVD-GNQAPSPARKRR-FDLLVR-GYKEIEV---FPSAS-QTDFDFVREIIGAI---P----DDVTIQVLTQ-RPELIERTFQACSG---RAIVHFYNS-IATDGARKCVEQAWRFEYSPESYTGTE------LEAKQVCDAVGEVI-IIFNL-----PN-VYADSIEWS--NRE-------SVILSLHAE-----------------------LGF-----TLG

                                                                                                                                     TGLHVK-LYEFI----RLICMLEVHDTTASTLDQAVDYWIEL-SVLVLINIGNE-PY--AT-AWATDTSAAIQRLRGFE------HTLVVDADWTN-TMRNNADQVYASD-TVFSIHM-V-ITSYLEHFVNAGLPLIIGEFG-HDH------------DTMAEAERLKLGYIGWSWMVYN--SPGERIFYGIASTA

                                                                                                                                                                        YNMMMGKVDDIATHVWLP---PSHSAS---A---ELKSLIGALHG---KGVQAIADIVINHQELKEWLLWLKSDGFDAWRLDARGYSPEMAKVYIDGTSPSLAVAEV-WD--NMAT----AHRQNLVNWVDKSAGMVFDFK------GIL---PGVMGWWP-------AKAVTFVD--VM--YAYILT----HPGIPCIFDHFFNW---------QIAALVAI---ILVVK----TSAH--NDY

                                                                                                                                                    ANIKLFSFTE--VN--------NPLNNLNFLVDMVVLF--SASNNPN---HLLTNR-KYLKPLQD---KGIKVILSI---AAFAQELKNTCDLYNLDGVFFDD---AARLAYETKQAMNKLVTVYVYSR----------------SF---NAYVDYAIHDGG----------SYDLAT-LA---------GMVMSSYA-----AQALRNIKG-YGGHMIF--MDPFT-ALK----LIAK

                                                                                                                                 LPV---AVT-QFLI-NGKP-----------KHE-LLVKDFNPY-EEVMQMVVIDE----VGLFN--SLHHHMQVMEEVVRRDKN-HPAVVMWSVAPASHLESAGYYLKMVIAHT-VTFVSNS---NYAAD--GA-PYVDVICLNS---WYHDYGH----LIQLQLATQFENW-IIQSEYG---T--YQKSLLEQYHLGLDQK---KYVVGELIWN----------------------FA

                                                                                                                           EK--VIEFPHA---------------AKLVAAAV------VTSDTFERAEALFEAGADAIVID--TAHSA--GVLRKIAEIRAHFP---------------------------------------------------------NRTLIAGN---------------TAEGARALYDAGVDVVKVG-------VPVTAIYDAAAVAREY-----GKTIIADGGIYSGDIVKALAAG----GNAVLGS--F--KGAASDIVFQL-GGIRS----AQFV------APNYS

                                                                                                                                        DGH-FI---------VLGFGTYA--PEPKSKAMEATKIAIDAGFRHIDS----YF---K----NEKEVGLAIRSK-GT-VKDIFYTSKLWHRPELVRPSLEDSLKNL-VDLYII----TWEAMEKCKDAGLAKSIGVSNFNRR-------------IL----LKY--VCN------QGKL--EFCKSKG--------------IVLV---LRYQLQRG----------IVV---AK----RIKENIQV-FEF-------PSED---------VIDS

                                                                                                                                                      YKLICYY--TSWSQ---FPDAI---DPFLCTHVIYS--FANWEW---VTLYDTLNTLKNRNP-----KLKTLLSVG--RTFIKSVPPFLRTHGFDGLDLA----LTALVKEMKAEFRLLLSAAVS--IDR------------DIAQISR-HLDFISLLTY--SPSN-DYAVSYML-GAP--------NKLVMGIPTF-ESVKNKARYLKN-LAG

                                                                                                                                     IKL-DGNV----------QLGLGV---WQASNEEVITAIQKALEVGYRSIDTA--AA----K-E-EG-GKALKN-ASVN-----ELFITTKLWDHKR-PREALLDSL-QL-IDLYLM-YVEAWKGMIELQKEGLIKSIGVCN-FQ-----------I--L--VTP-----VINQI----MQQRQ--LHAWNATHK-----------IQTES--IRWHLDSG----------VVIP---K---SRIAENFDV-WDF----------------DELGEIAKLD

                                                                                                                                                      MKTQ--YF----DALEQWA-WMGAALQKKVFISTCI---PIMR-YNPAIVAQTFATLRQMYP-----GRVGVAVGAGRQDMTVEAVKVMRML-VPLYFS-GM---GPKGAKLAGMYGDHLMTVA---------------APSTLKVTIPKF-HAMLIWYSVDALRMCA--EIRFKEAG---------NHFCLGNS------------------------------FGIDIFKEVIPA

                                                                                                                                      FP----NIS-SDES-RFSHRGILI-DTYLP-VK-ILK-LDM-AFKFNVLHWH--IV--FPYQS-P-VRMVIEYARLRG------IRVLPEFDT-YSFLTTFFKEISEVFPDFIHLGG---ESFYIQKVLDIINKGSIVW------------------DD--KA-KLATIVEVWKD------S---AYPEELSRVTAS-----GFPVILSAPW--YK--VEPLDF---FIGGEACRAS------------------------DVRD-RLTR